Med, a cell-surface localized protein regulating a competence transcription factor gene, comK, in bacillus subtilis

Bioscience, Biotechnology and Biochemistry

Volumn 66, Issue 4, 2002, Pages 892-896

  Ogura, Mitsuo ^a   Hashimoto, Hitoshi ^a   Tanaka, Teruo ^a  

^a TOKAI UNIVERSITY   (Japan)

Author keywords

Competence development; Med; Protein localization

Indexed keywords

BACTERIAL PROTEIN; COMK PROTEIN, BACILLUS SUBTILIS; LIGAND; MED PROTEIN, BACILLUS SUBTILIS; PRIMER DNA; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ARTICLE; BACILLUS SUBTILIS; CHEMISTRY; CONSENSUS SEQUENCE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; BACILLUS SUBTILIS; BACTERIAL PROTEINS; BASE SEQUENCE; CONSENSUS SEQUENCE; DNA PRIMERS; GENE EXPRESSION REGULATION, BACTERIAL; LIGANDS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

BACILLUS SUBTILIS;

EID: 0036547593     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.66.892     Document Type: Article

References (21)

1. Dubnau, D., Binding and transport of transforming DNA by Bacillus subtilis: the role of type-IV pilin-like proteins. Gene., 192, 191-198 (1997).
2. Dubnau, D., Genetic exchange and homologous recombination. In “Bacillus subtilis and other Grampositive bacteria: biochemistry, physiology, and molecular genetics”, eds. Sonenshein, A. L., Hoch, J. A., and Losick, R., American Society for Microbiology, Washington, D.C., pp. 555-585 (1993).
3. Grossman, A. D., Genetic networks controlling the initiation of sporulation and the development of genetic competence in Bacillus subtilis. Ann. Rev. Genetics., 29, 477-508 (1995).
4. Lazazzera, B. A. and Grossman, A. D., The ins and outs of peptide signaling. Trends Microbiol., 6, 288-294 (1998).
5. Sutcliffe, I. C. and Russell, R. R. Lipoproteins of gram-positive bacteria. J. Bacteriol., 177, 1123-1128 (1995).
6. Dartois, V., Djavakhishvili, T., and Hoch, J. A., KapB is a lipoprotein required for KinB signal transduction and activation of the phosphorelay to sporulation in Bacillus subtilis. Mol. Microbiol., 26, 1097-1108 (1997).
7. Leskela, S., Wahlstrom, E., Kontinen, V. P., and Sarvas, M., Lipid modification of prelipoproteins is dispensable for growth but essential for efficient protein secretion in Bacillus subtilis: characterization of the lgt gene. Mol. Microbiol., 31, 1075-1085 (1999).
8. Tjalsma, H., Kontinen, V. P., Pragai, Z., Wu, H., Meima, R., Venema, G., Bron, S., Sarvas, M., and van Dijl, J. M., The role of lipoprotein processing by signal peptidase II in the Gram-positive eubacterium Bacillus subtilis. Signal peptidase II is required for the efficient secretion of alpha-amylase, a nonlipoprotein. J. Biol. Chem., 274, 1698-1707 (1999).
9. Hahn, J., Luttinger, A., and Dubnau, D., Regulatory inputs for the synthesis of ComK, the competence transcription factor of Bacillus subtilis. Mol. Microbiol., 21, 763-775 (1996).
10. Msadek, T., Kunst, F., and Rapoport, G., MecB of Bacillus subtilis is a pleiotropic regulator of the ClpC ATPase family, controlling competence gene expression and survival at high temperature. Proc. Natl. Acad. Sci. USA., 91, 5788-5792 (1994).
11. Turgay, K., Hamoen, L. W., Venema, G., and Dubnau, D., Biochemical characterization of a molecular switch involving the heat shock protein ClpC, which controls the activity of ComK, the competence transcription factor of Bacillus subtilis. Genes Dev., 11, 119-128 (1997).
12. Turgay, K., Hahn, J., Burghoorn, J., and Dubnau, D., Competence in Bacillus subtilis is controlled by regulated proteolysis of a transcription factor. EMBO J., 17, 6730-6738 (1998).
13. Ogura, M., Liu, L., Lacelle, M., Nakano, M. M., and Zuber, P., Mutational analysis of ComS: evidence for the interaction of ComS and MecA in the regulation of competence development in Bacillus subtilis. Mol. Microbiol., 32, 799-812 (1999).
14. Hamoen, L. W., Van Werkhoven, A. F., Bijlsma, J. J., Dubnau, D., and Venema, G., The competence transcription factor of Bacillus subtilis recognizes short A/T-rich sequences arranged in a unique, flexible pattern along the DNA helix. Genes Dev., 12, 1539-1550 (1998).
15. Ogura, M., Ohshiro, Y., Hirao, S., and Tanaka, T., A new Bacillus subtilis gene, med, encodes a positive regulator of comK. J. Bacteriol., 179, 6244-6253 (1997).
16. Ogura, M. and Tanaka, T., Bacillus subtilis comZ (yjzA) negatively affects expression of comG but not comK. J. Bacteriol., 182, 4992-4994 (2000).
17. Derman, A. I. and Beckwith, J., Escherichia coli alkaline phosphatase fails to acquire disulfide bonds when retained in cytoplasm. J. Bacteriol., 173, 7719-7722 (1991).
18. Dartois, V., Coppee, J. Y., Colson, C., and Baulard, A., Genetic analysis and overexpression of lipolytic activity in Bacillus subtilis. Appl. Environ. Microbiol., 60, 1670-1673 (1994).
19. Navarre, W. W. and Schneewind O., Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope. Microbiol. Mol. Biol. Rev., 63, 174-229 (1999).
20. Adams, M. D., Wagner, L. M., Graddis, T. J., Landick, R., Antonucci, T. K., Gibson, A. L., and Oxender, D. L., Nucleotide sequence and genetic characterization reveal six essential genes for the LIVI and LS transport systems of Escherichia coli. J. Biol. Chem., 265, 11436-11443 (1990).
21. Roland, T. and Saier Jr, M. H., Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteria. Microbiol. Rev., 57, 320-346 (1993).