New insights into the mechanism of virus-induced membrane fusion

Trends in Biochemical Sciences

Volumn 27, Issue 4, 2002, Pages 183-190

  Peisajovich, Sergio G ^a   Shai, Yechiel ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; HYBRID PROTEIN; PROTEIN; PROTEIN F; UNCLASSIFIED DRUG;

BIOLOGICAL MODEL; CELL MEMBRANE; DISSECTION; HEAD; HYDROPHOBICITY; MEMBRANE FUSION; NONHUMAN; PARAMYXOVIRUS; PATHOGENICITY; PREDICTION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; REVIEW; STRUCTURE ANALYSIS; VIRUS; VIRUS ENVELOPE; VIRUS INFECTION; VIRUS INHIBITION;

AMINO ACID SEQUENCE; MEMBRANE FUSION; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PARAMYXOVIRIDAE; SEQUENCE HOMOLOGY, AMINO ACID; VIRAL FUSION PROTEINS;

PARAMYXOVIRIDAE; RNA VIRUSES;

EID: 0036534449     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0004(01)02050-3     Document Type: Review

References (42)

1. Protein-mediated membrane fusion
2. Virus-cell and cell-cell fusion
3. Paramyxoviridae: The viruses and their replication
4. Membrane fusion
5. Coiled coils in both intracellular vesicle and viral membrane fusion
6. Activation of the Sendai virus fusion protein (F) involves a conformational change with exposure of a new hydrophobic region
7. Analysis of respiratory syncytial virus F, G, and SH proteins in cell fusion
8. Paramyxovirus fusion: A hypothesis for changes
9. Detection of an interaction between the HN and F proteins in Newcastle disease virus-infected cells
10. Alternative mechanisms of interaction between homotypic and heterotypic parainfluenza virus HN and F proteins
11. Measles virus glycoproteins: Studies on the structure and interaction of the haemagglutinin and fusion proteins
12. Association of the parainfluenza virus fusion and hemagglutinin-neuraminidase glycoproteins on cell surfaces
13. A peptide from the heptad repeat of human immunodeficiency virus gp41 shows both membrane binding and coiled-coil formation
14. Membrane-induced step in the activation of Sendai virus fusion protein
15. Direct evidence that the N-terminal heptad repeat of Sendai virus fusion protein participates in membrane fusion
16. The ectodomain of HA2 of influenza virus promotes rapid pH dependent membrane fusion
17. H+-induced membrane insertion of influenza virus hemagglutinin involves the HA2 amino-terminal fusion peptide but not the coiled coil region
18. The F1 protein of paramyxoviruses has two fusion peptides: Implications for the mechanism of membrane fusion
19. Sendai virus internal fusion peptide: Structural and functional characterization and a plausible mode of viral entry inhibition
20. Participation of two fusion peptides in measles virus-induced membrane fusion: Emerging similarity with other Paramyxoviruses
21. Structural basis for paramyxovirus-mediated membrane fusion
22. The structure of the fusion glycoprotein of Newcastle Disease Virus suggests a novel paradigm for the molecular mechanism of membrane fusion
23. Membrane fusion proteins of enveloped animal viruses
24. Determination of the equilibrium micelle-inserting position of the fusion peptide of gp41 of human immunodeficiency virus type 1 at amino acid resolution by exchange broadening of amide proton resonances
25. Role of a single amino acid at the amino terminus of the simian virus 5 F2 subunit in syncytium formation
26. Hemagglutinin-neuraminidase-independent fusion activity of simian virus 5 fusion (F) protein: Difference in conformation between fusogenic and nonfusogenic F proteins on the cell surface
27. Temperature dependence of fusion by Sendai virus
28. A single amino acid change in the Newcastle disease virus fusion protein alters the requirement for HN protein in fusion
29. A leucine zipper motif in the ectodomain of Sendai virus fusion protein assembles in solution and in membranes and specifically binds biologically-active peptides and the virus
30. Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution
31. Structure of influenza haemagglutinin at the pH of membrane fusion
32. Receptor binding and membrane fusion in virus entry: The influenza hemagglutinin
33. A spring-loaded mechanism for the conformational change of influenza hemagglutinin
34. A mechanism of protein-mediated fusion: Coupling between refolding of the influenza hemagglutinin and lipid rearrangements
35. Structural characterization of the human respiratory syncytial virus fusion protein core
36. Electron microscopy of the human respiratory syncytial virus fusion protein and complexes that it forms with monoclonal antibodies
37. Mutations in the fusion peptide and adjacent heptad repeat inhibit folding or activity of the Newcastle disease virus fusion protein
38. Proper spacing between heptad repeat B and the transmembrane domain boundary of the paramyxovirus SV5 F protein is critical for biological activity
39. Mutational analysis of the membrane proximal heptad repeat of the Newcastle Disease virus fusion protein
40. A synthetic peptide corresponding to a conserved heptad repeat domain is a potent inhibitor of Sendai virus-cell fusion: An emerging similarity with functional domains of other viruses
41. Analysis of a peptide inhibitor of paramyxovirus (NDV) fusion using biological assays, NMR, and molecular modeling
42. Mode of action of an antiviral peptide from HIV-1. Inhibition at a post-lipid mixing stage