Hemagglutinin-neuraminidase-independent fusion activity of simian virus 5 fusion (f) protein: Difference in conformation between fusogenic and nonfusogenic F proteins on the cell surface

Journal of Virology

Volumn 75, Issue 19, 2001, Pages 8999-9009

  Tsurudome, M ^a   Ito, M ^a   Nishio, M ^a   Kawano, M ^a   Komada, H ^a   Ito, Y ^a  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CELL SURFACE PROTEIN; EPITOPE; FORMALDEHYDE; HN PROTEIN; LEUCINE; MONOCLONAL ANTIBODY; MUTANT PROTEIN; PROTEIN SUBUNIT; VIRUS FUSION PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL FUSION; CONTROLLED STUDY; FLOW CYTOMETRY; HEATING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARAMYXOVIRUS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; SIMIAN VIRUS; VIRUS STRAIN;

AMINO ACID SEQUENCE; BASE SEQUENCE; HELA CELLS; HN PROTEIN; HUMANS; MOLECULAR SEQUENCE DATA; PARAMYXOVIRINAE; PROTEIN CONFORMATION; VIRAL FUSION PROTEINS; VIRUS REPLICATION;

EID: 0034853335     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.19.8999-9009.2001     Document Type: Article

References (60)

1. Structural basis for paramyxovirus-mediated membrane fusion
2. Regions on the hemagglutinin-neuraminidase proteins of human parainfluenza virus type-1 and Sendai virus important for membrane fusion
3. Structure of influenza haemagglutinin at the pH of membrane fusion
4. Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41
5. Electron microscopy of the human respiratory syncytial virus fusion protein and complexes that it forms with monoclonal antibodies
6. Sequence analysis of the gene encoding the fusion glycoprotein of pneumonia virus of mice suggests possible conserved secondary structure elements in paramyxovirus fusion glycoproteins
7. Core structure of gp41 from the HIV envelope glycoprotein
8. HIV entry and its inhibition
9. Parainfluenza viruses
10. Functional chimeric HN glycoproteins derived from Newcastle disease virus and human parainfluenza virus-3
11. Mutations in the Newcastle disease virus hemagglutinin-neuraminidase protein that interfere with its ability to interact with the homologous F protein
12. Localization of a domain on the paramyxovirus attachment protein required for the promotion of cellular fusion by its homologous fusion protein spike
13. Paramyxovirus fusion protein: A conformational change on cleavage activation
14. Paramyxovirus fusion protein: Characterization of the core trimer, a rod-shaped complex with helices in anti-parallel orientation
15. The fusion and hemagglutinin-neuraminidase glycoproteins of human parainfluenza virus 3 are both required for fusion
16. Function and immunogenicity of human parainfluenza virus 3 glycoproteins expressed by recombinant adenoviruses
17. Purification of the fusion protein of Sendai virus: Analysis of the NH2-terminal sequence generated during precursor activation
18. A leucine zipper motif in the ectodomain of Sendai virus fusion protein assembles in solution and in membranes and specifically binds biologically-active peptides and the virus
19. Structure-function study of a heptad repeat positioned near the transmembrane domain of Sendai virus fusion protein which blocks virus-cell fusion
20. A new technique for the assay of infectivity of human adenovirus 5 DNA
21. Paramyxovirus mediated cell fusion requires co-expression of both the fusion and hemagglutininneuraminidase glycoproteins
22. Trypsin action on the growth of Sendai virus in tissue culture cells. III. Structural differences of Sendai virus grown in eggs and tissue culture cells
23. Restoration of the fusion activity of L cell-borne Sendai virus by trypsin
24. Biological activity of paramyxovirus fusion proteins: Factors influencing formation of syncytia
25. Activation of the Sendai virus fusion protein (F) involved a conformational change with exposure of a new hydrophobic region
26. Functional interactions between the fusion protein and hemagglutinin-neuraminidase of human parainfluenza viruses
27. Role of a single amino acid at the amino terminus of the simian virus 5 F2 subunit in syncytium formation
28. An amino acid in the heptad repeat I domain is important for the haemagglutininneuraminidase-independent fusing activity of simian virus 5 fusion protein
29. Changes in conformation and charge paralleling proteolytic activation of Newcastle disease virus glycoproteins
30. Paramyxovirus fusion: A hypothesis for changes
31. Paramyxoviridae: The viruses and their replication
32. The paramyxovirus simian virus 5 hemagglutinin-neuraminidase glycoprotein, but not the fusion glycoprotein, is internalized via coated pits and enters the endocytic pathway
33. The core of the respiratory syncytial virus fusion protein is a trimeric coiled coil
34. Complementation between avirulent Newcastle disease virus and a fusion protein gene expressed from a retrovirus vector: Requirements for membrane fusion
35. Mutations located on both Fl and F2 subunits of the Newcastle disease virus fusion protein confer resistance to neutralization with monoclonal antibodies.
36. Fusion properties of cells constitutively expressing human parainfluenza virus type 4A haemagglutinin-neuraminidase and fusion glycoproteins
37. Membrane penetration of Sendai virus glycoproteins during the early stages of fusion with liposomes as determined by hydrophobic photoaffinity labeling
38. Expression at the cell surface of biologically active fusion and hemagglutinin/neuraminidase proteins of the paramyxovirus simian virus 5 from cloned cDNA
39. Fusion protein of the paramyxovirus SV5: Destabilizing and stabilizing mutants of fusion activation
40. Virus taxonomy - 1999. The universal system of virus taxonomy, updated to include the new proposals ratified by the international committee on taxonomy of viruses during 1998
41. Syncytium formation by recombinant vaccinia viruses carrying bovine parainfluenza 3 virus envelope protein genes
42. Identification and biological activities of paramyxovirus glycoproteins. Activation of cell fusion, hemolysis, and infectivity by proteolytic cleavage of an inactive precursor protein of Sendai virus
43. A single amino acid change in the Newcastle disease virus fusion protein alters the requirement for HN protein in fusion
44. Detection of an interaction between the HN and F proteins in Newcastle disease virus-infected cells
45. Expression of fusion regulatory proteins (FRPs) on human peripheral blood lymphocytes. Induction of homotypic cell aggregation and formation of multinucleated giant cells by anti-FRP-1 monoclonal antibody
46. Functional interaction of paramyxovirus glycoproteins: Identification of a domain in Sendai virus HN which promotes cell fusion
47. Expression of mumps virus glycoproteins in mammalian cells from cloned cDNAs: Both F and HN proteins are required for cell fusion
48. Identification of amino acids relevant to three antigenic determinants on the fusion protein of Newcastle disease virus that are involved in fusion inhibition and neutralization
49. Antigenic and structural properties of a paramyxovirus simian virus 41 (SV41) reveal a close relationship with human parainfluenza type 2 virus
50. Identification of regions on the fusion protein of human parainfluenza type 2 virus which are required for haemagglutininneuraminidase proteins to promote cell fusion
51. Identification of regions on the hemagglutinin-neuraminidase protein of human parainfluenza virus type 2 important for promoting cell fusion
52. Extensive antigenic diversity among human parainfluenza type 2 virus isolates and immunological relationships among paramyxoviruses revealed by monoclonal antibodies
53. Monoclonal antibodies against the glycoproteins of mumps virus: Fusion inhibition by anti-HN monoclonal antibody
54. Monoclonal antibodies to three structural proteins of Newcastle disease virus: Biological characterization with particular reference to the conformational change of envelope glycoproteins associated with proteolytic cleavage
55. Intracellular processing of the paramyxovirus F protein: Critical role in the predicted amphipathic alpha helix adjacent to the fusion domain
56. Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain
57. Atomic structure of the ectodomain from HIV-1 gp41
58. Association of the parainfluenza virus fusion and hemagglutinin-neuraminidase glycoproteins on cell surfaces
59. Location of neutralizing epitopes on the fusion protein of Newcastle disease virus strain Beaudette C
60. Structural characterization of the human respiratory syncytial virus fusion protein core