Infectious disease experimentation involving human volunteers

Clinical Infectious Diseases

Volumn 34, Issue 7, 2002, Pages 963-971

  Rosenbaum, Julie Rothstein ^a   Sepkowitz, Kent A ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL FEATURE; DISEASE TRANSMISSION; ETHICS; HEALTH SURVEY; HEPATITIS; HUMAN; INFECTION RISK; MALARIA; MEDICAL LITERATURE; MORTALITY; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; TREATMENT OUTCOME; UPPER RESPIRATORY TRACT INFECTION; VIRUS ISOLATION; VOLUNTEER;

BIOMEDICAL AND BEHAVIORAL RESEARCH; EMPIRICAL APPROACH;

COMMUNICABLE DISEASES; ETHICS, MEDICAL; HEPATITIS; HUMAN EXPERIMENTATION; HUMANS; MALARIA; RESEARCH; RESPIRATORY TRACT INFECTIONS; RISK ASSESSMENT;

EID: 0036531892     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/339328     Document Type: Review

References (71)

1. The etiology of infectious hepatitis
2. Adventures among viruses III: The puzzle of the common cold
3. Recent advances in the knowledge of virus hepatitis
4. Autoexperimentation: An unappreciated tradition in medical science
5. Use of the oral neuraminidase inhibitor oseltamivir in experimental human influenza: Randomized controlled trials for prevention and treatment
6. Safety and efficacy of the neuraminidase inhibitor GG167 in experimental human influenza
7. Human experimentation in infectious diseases
8. The use of volunteers in medical virology
9. Research on healthy volunteers: A report of the royal college of physicians
10. Commentary: Safety of participants in non-therapeutic research must be ensured
11. Untreated syphilis in the male Negro: Background and current status of patients in the Tuskegee study
12. Homologous serum jaundice: Transmission experiments in human volunteers
13. Note on acute hepatitis and yellow fever immunization
14. Hepatitis following injection of mumps convalescent plasma
15. Virus jaundice: Epidemic hepatitis in relation to immunization with human serum
16. Jaundice occurring one to four months after transfusion of blood or plasma
17. Jaundice in army personnel in the western region of the United States and its relation to vaccination against yellow fever
18. Jaundice following yellow-fever immunisation: Transmission by intranasal instillation
19. Hepatitis due to the injection of homologous blood products in human volunteers
20. Transmission experiments in serum jaundice and infectious hepatitis
21. Homologous serum hepatitis and infectious (epidemic) hepatitis: Studies in volunteers bearing on immunological and other characteristics of the etiological agents
22. Oral administration to volunteers of feces from patients with homologous serum hepatitis and infectious (epidemic) hepatitis
23. Homologous serum hepatitis and infectious (epidemic) hepatitis: Experimental study of immunity and cross immunity in volunteers - A preliminary report
24. Hepatitis E virus transmission to a volunteer
25. Atypical strain of hepatitis E. virus (HEV) from North India
26. The transmission of primary atypical pneumonia to human volunteers II results of inoculation
27. The transmission of primary atypical pneumonia to human volunteers III: Clinical features
28. Studies in the common cold IV: Experimental transmission of the common cold to anthropoid apes and human beings by means of a filterable agent
29. Adventures among viruses III: The puzzle of the common cold
30. Cantor Lecture: The common cold
31. The medical research council common cold unit, Harvard Hospital, Salisbury, Wilts, England
32. The natural history of the common cold
33. Transmission of the common cold to volunteers under controlled conditions III: The effect of chilling of the subjects upon susceptibility
34. Mechanisms of transmission of rhinovirus infections
35. Transmission of experimental rhinovirus: Colds in volunteer married couples
36. Aerosol transmission of rhinovirus colds
37. Effects of experimentally induced colds on aspects of memory
38. Increased levels of interleukin-1 are detected in nasal secretions of volunteers during experimental rhinovirus colds
39. Transmission of the common cold to volunteers under controlled conditions IV: Specific immunity to the common cold
40. Experimental proof of the mosquito-malaria theory
41. Sidelights on malaria in man obtained by subinoculation experiments
42. Clinical and parasitological observations on induced malaria
43. Prison malaria; convicts expose themselves to disease so doctors can study it
44. Multidrug-resistant strain of Plasmodium falciparum from eastern Colombia
45. Letter: Research with Plasmodium falciparum in volunteers
46. Non-A, non-B hepatitis after experimental transmission of malaria by inoculation of blood
47. Laboratory methods for the conduct of experimental malaria challenge of volunteers
48. Clinical manifestations of Plasmodium falciparum malaria experimentally induced by mosquito challenge
49. Plasmodium falciparum-infected Anopheles stephensi inconsistently transmit malaria to humans
50. Quantitation of Plasmodium falciparum sporozoites transmitted in vitro by experimentally infected Anopheles gambiae and Anopheles stephensi
51. Safety and efficacy of a recombinant DNA Plasmodium falciparum sporozoite vaccine
52. Safety, immunogenicity, and efficacy of a malaria sporozoite vaccine administered with monophosphoryl lipid A, cell wall cytoskeleton of mycobacteria, and squalene as adjuvant
53. Antisporozoite vaccine for malaria: Experimental basis and current status
54. Mefloquine failure in a case of falciparum malaria induced with a multi-drug resistant isolate in a non-immune subject
55. Azithromycin prophylaxis against a chloroquine-resistant strain of Plasmodium falciparum
56. The Belmont report: Ethical principles and guidelines for the protection of human subjects of research
57. A serological follow-up of the 1942 epidemic of post-vaccination hepatitis in the united states army
58. Mortality follow-up of the 1942 epidemic of hepatitis B in the US army
59. Experimental gonococcic urethritis in human volunteers
60. Research involving prisoners
61. Law and public policy in human studies research