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Volumn 57, Issue 3, 2002, Pages 235-242

Leukotriene modifiers: Novel therapeutic opportunities in asthma

Author keywords

Asthma; Leukotriene modifiers; Novel therapeutic opportunity

Indexed keywords

1 [2 METHOXY 4 [(PHENYLSULFONYLAMINO)CARBONYL]BENZYL] 1H INDAZOLE 6 CARBAMIC ACID CYCLOPENTYL ESTER; 15 HYDROXYICOSATETRAENOIC ACID; 2 CYCLOPENTYL 2 [4 (2 QUINOLINYLMETHOXY)PHENYL]ACETIC ACID; 3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 (2 QUINOLINYLMETHOXY) 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; 3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; 7 [3 (4 ACETYL 3 HYDROXY 2 PROPYLPHENOXY) 2 HYDROXYPROPOXY] 4 OXO 8 PROPYL 4H 1 BENZOPYRAN 2 CARBOXYLIC ACID; ALPHA PENTYL 3 (2 QUINOLYLMETHOXY)BENZYL ALCOHOL; ANTIASTHMATIC AGENT; BAY Y 1015; LEUKOTRIENE DERIVATIVE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LIPOXYGENASE INHIBITOR; QUINOLINE; ZAFIRLUKAST; INDOLE DERIVATIVE; LEUKOTRIENE; SLOW REACTING SUBSTANCE; TOLUENESULFONIC ACID DERIVATIVE;

EID: 0036516857     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(02)01209-0     Document Type: Review
Times cited : (14)

References (28)
  • 1
    • 0023177955 scopus 로고
    • Leukotrienes and lipoxins: Structures, biosynthesis, and biological effects
    • Samuelsson B., Dahlen S.E., Lindgren J.A., Rouzer C.A., Serhan C.N. Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science. 237:1987;1171-1176.
    • (1987) Science , vol.237 , pp. 1171-1176
    • Samuelsson, B.1    Dahlen, S.E.2    Lindgren, J.A.3    Rouzer, C.A.4    Serhan, C.N.5
  • 2
    • 0010641260 scopus 로고
    • Discovery of Accolate™ [ICI 204,219]: A peptide leukotriene antagonist for asthma
    • V.J. Merluzzi, & J. Adams. Boston: Birkhauser
    • Brown F.J. Discovery of Accolate™ [ICI 204,219]: a peptide leukotriene antagonist for asthma. Merluzzi V.J., Adams J. The Search for Anti-inflammatory Drugs. 1995;161-190 Birkhauser, Boston.
    • (1995) The Search for Anti-inflammatory Drugs , pp. 161-190
    • Brown, F.J.1
  • 4
    • 0025302763 scopus 로고
    • Evaluation of a series of peptidoleukotriene antagonists: Synthesis and structure/activity relationships of 1,6-disubstituted indoles and indazoles
    • Brown F.J., Yee Y.K., Cronk L.A., Hebbel K.C., Krell R.D., Snyder D.W. Evaluation of a series of peptidoleukotriene antagonists: synthesis and structure/activity relationships of 1,6-disubstituted indoles and indazoles. J. Med. Chem. 33:1990;1771-1781.
    • (1990) J. Med. Chem. , vol.33 , pp. 1771-1781
    • Brown, F.J.1    Yee, Y.K.2    Cronk, L.A.3    Hebbel, K.C.4    Krell, R.D.5    Snyder, D.W.6
  • 5
    • 0013611277 scopus 로고    scopus 로고
    • The challenge of drug discovery: Developing leukotriene antagonists
    • S.T. Holgate, & S.E. Dahlen. Blackwell Science
    • Bernstien P.R. The challenge of drug discovery: developing leukotriene antagonists. Holgate S.T., Dahlen S.E. SRS-A to Leukotrienes. 1997;171-187 Blackwell Science.
    • (1997) SRS-A to Leukotrienes , pp. 171-187
    • Bernstien, P.R.1
  • 6
    • 0023485873 scopus 로고
    • In vivo pharmacology of ICI 198,615: A novel, potent and selective peptide leukotriene antagonist
    • Krell R.D., Giles R.E., Yee Y.K., Snyder D.W. In vivo pharmacology of ICI 198,615: a novel, potent and selective peptide leukotriene antagonist. J. Pharmacol. Exp. Ther. 243:1987;557-564.
    • (1987) J. Pharmacol. Exp. Ther. , vol.243 , pp. 557-564
    • Krell, R.D.1    Giles, R.E.2    Yee, Y.K.3    Snyder, D.W.4
  • 8
    • 0023706663 scopus 로고
    • Structure-activty relationships based on the peptide leukotriene receptor antagonist ICI 198,615: Enhancement of potency
    • Yee Y.K., Brown F.J., Hebbel K.C., Cronk L.A., Snyder D.W., Krell R.D. Structure-activty relationships based on the peptide leukotriene receptor antagonist ICI 198,615: enhancement of potency. Ann. New York Acad. Sci. 524:1988;458-461.
    • (1988) Ann. New York Acad. Sci. , vol.524 , pp. 458-461
    • Yee, Y.K.1    Brown, F.J.2    Hebbel, K.C.3    Cronk, L.A.4    Snyder, D.W.5    Krell, R.D.6
  • 10
    • 0000240125 scopus 로고    scopus 로고
    • The sheep as a model of the late asthmatic response
    • D. Raeburn, & M.A. Giembycz. Basel: Birkhauser
    • Abraham W.M. The sheep as a model of the late asthmatic response. Raeburn D., Giembycz M.A. Airways Smooth Muscle: Modeling the Asthmatic Response In Vivo. 1996;171-189 Birkhauser, Basel.
    • (1996) Airways Smooth Muscle: Modeling the Asthmatic Response in Vivo , pp. 171-189
    • Abraham, W.M.1
  • 12
    • 0031057451 scopus 로고    scopus 로고
    • Effectiveness of the leukotriene receptor antagonist zafirlukast for mild-to-moderate asthma: A randomized, double-blind, placebo-controlled trial
    • Suissa S., Dennis R., Ernst P., Sheehy O., Wood-Dauphinee S. Effectiveness of the leukotriene receptor antagonist zafirlukast for mild-to-moderate asthma: a randomized, double-blind, placebo-controlled trial. Ann. Intern. Med. 126:1997;177-183.
    • (1997) Ann. Intern. Med. , vol.126 , pp. 177-183
    • Suissa, S.1    Dennis, R.2    Ernst, P.3    Sheehy, O.4    Wood-Dauphinee, S.5
  • 14
    • 0027964479 scopus 로고
    • Localization of 5-lipoxygenase to the nucleus of unstimulated rat basophilie leukemia cells
    • Brock T.G., Paine R. III, Peters-Golden M. Localization of 5-lipoxygenase to the nucleus of unstimulated rat basophilie leukemia cells. J. Biol. Chem. 269:1994;22059-22066.
    • (1994) J. Biol. Chem. , vol.269 , pp. 22059-22066
    • Brock, T.G.1    Paine III, R.2    Peters-Golden, M.3
  • 15
    • 0027093272 scopus 로고
    • A23187-induced transiocation of 5-lipoxygenase in osteosarcoma cells
    • Kargman S., Vickers P.J., Evans J.F. A23187-induced transiocation of 5-lipoxygenase in osteosarcoma cells. J. Cell. Biol. 119:1992;1701-1709.
    • (1992) J. Cell. Biol. , vol.119 , pp. 1701-1709
    • Kargman, S.1    Vickers, P.J.2    Evans, J.F.3
  • 17
    • 0028863083 scopus 로고
    • BAY X-1005-leukotriene synthesis inhibitor
    • Muller-Peddinghaus R., Raddatz S. BAY X-1005-leukotriene synthesis inhibitor. Drugs Future. 20:1995;996-1000.
    • (1995) Drugs Future , vol.20 , pp. 996-1000
    • Muller-Peddinghaus, R.1    Raddatz, S.2
  • 18
    • 0028238897 scopus 로고
    • Inversely-correlated inhibition of human 5-lipoxygenase activity by BAY X-1005 and other quinoline derivatives in intact cells and a cell-free system - Implications for the function of 5-Iipoxygenase activating protein
    • Hatzelmann A., Goosens J., Fruchtmann R., Mohrs K.H., Raddatz S., Muller-Peddinghaus R. Inversely-correlated inhibition of human 5-lipoxygenase activity by BAY X-1005 and other quinoline derivatives in intact cells and a cell-free system - implications for the function of 5-Iipoxygenase activating protein. Biochem. Pharmacol. 47:1994;2259-2268.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 2259-2268
    • Hatzelmann, A.1    Goosens, J.2    Fruchtmann, R.3    Mohrs, K.H.4    Raddatz, S.5    Muller-Peddinghaus, R.6
  • 20
    • 0028280329 scopus 로고
    • (R)-2-[4-(Quinolin-2-yl-methoxy)phenylj-2-cyclopentyl] acetic acid (BAY X-1005), a potent leukotriene synthesis inhibitor: Effects on anti-IgE challenge in human airways
    • Gorenne I., Labat C., Gascard J.P., Norel X., Muller-Peddinghaus R., Mohrs K.H., Taylor W.A., Gardiner P.J., Brink C. (R)-2-[4-(Quinolin-2-yl- methoxy)phenylj-2-cyclopentyl] acetic acid (BAY X-1005), a potent leukotriene synthesis inhibitor: effects on anti-IgE challenge in human airways. J. Pharmacol. Exp. Ther. 268:1994;868-872.
    • (1994) J. Pharmacol. Exp. Ther. , vol.268 , pp. 868-872
    • Gorenne, I.1    Labat, C.2    Gascard, J.P.3    Norel, X.4    Muller-Peddinghaus, R.5    Mohrs, K.H.6    Taylor, W.A.7    Gardiner, P.J.8    Brink, C.9
  • 23
    • 1642346609 scopus 로고
    • Effect of the leukotriene synthesis inhibitor BAY X-1005 on the murine zymosan-accelerated collagen-induced arthritis (ZymCIA)
    • Joosten A.B., Muller-Peddinghaus R., van den Berg W.B. Effect of the leukotriene synthesis inhibitor BAY X-1005 on the murine zymosan-accelerated collagen-induced arthritis (ZymCIA). Inflamm. Res. 44:(Suppl. 3):1995;S261.
    • (1995) Inflamm. Res. , vol.44 , Issue.SUPPL. 3 , pp. 261
    • Joosten, A.B.1    Muller-Peddinghaus, R.2    Van Den Berg, W.B.3
  • 26
    • 0029762221 scopus 로고    scopus 로고
    • Non pharmacokinetic or pharmacodynamic interaction between theophyline and the leukotriene biosynthesis inhibitor BAY X-1005
    • Groen H., Moesker H.L., Leeuwenkamp O.R., Sollie F.A.E., Jonkman J.H.G. Non pharmacokinetic or pharmacodynamic interaction between theophyline and the leukotriene biosynthesis inhibitor BAY X-1005. J. Clin. Pharmacol. 36:1996;639-646.
    • (1996) J. Clin. Pharmacol. , vol.36 , pp. 639-646
    • Groen, H.1    Moesker, H.L.2    Leeuwenkamp, O.R.3    Sollie, F.A.E.4    Jonkman, J.H.G.5
  • 27
    • 0030925781 scopus 로고    scopus 로고
    • Inhibiton of allergen induced airway obstruction and leukotriene generation in atopic asthmatic subjects by the leukotriene biosynthesis inhibitor BAY X-1005
    • Dahlen B., Kumlin M., Ihre E., Zetterstrom O., Dalhen S.E. Inhibiton of allergen induced airway obstruction and leukotriene generation in atopic asthmatic subjects by the leukotriene biosynthesis inhibitor BAY X-1005. Thorax. 52:1997;342-347.
    • (1997) Thorax , vol.52 , pp. 342-347
    • Dahlen, B.1    Kumlin, M.2    Ihre, E.3    Zetterstrom, O.4    Dalhen, S.E.5
  • 28
    • 0030996540 scopus 로고    scopus 로고
    • Attenuation of early and late phase allergen-induced bronchoconstrction in asthmatic subjects by a 5-lipoxygenase activating protein antagonist, BAY X-1005
    • Hamilton A.L., Watson R.M., Wyile G., O'Byrne P.M. Attenuation of early and late phase allergen-induced bronchoconstrction in asthmatic subjects by a 5-lipoxygenase activating protein antagonist, BAY X-1005. Thorax. 52:1997;348-354.
    • (1997) Thorax , vol.52 , pp. 348-354
    • Hamilton, A.L.1    Watson, R.M.2    Wyile, G.3    O'Byrne, P.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.