-
1
-
-
0017719024
-
Atherosclerosis: The low-density lipoprotein receptor hypothesis
-
Goldstein J.L., Brown M.S. Atherosclerosis: the low-density lipoprotein receptor hypothesis. Metabolism. 26:1977;1257-1275.
-
(1977)
Metabolism
, vol.26
, pp. 1257-1275
-
-
Goldstein, J.L.1
Brown, M.S.2
-
2
-
-
0000710395
-
Familial hypercholesterolemia
-
J.B. Starburg, J.B. Wyngaarden, & D.S. Fredrickson. New York: McGraw Hill
-
Goldstein J.L., Hobbs H.H., Brown M.S. Familial hypercholesterolemia. Starburg J.B., Wyngaarden J.B., Fredrickson D.S. The molecular and metabolic basis of inhibited disease. 7th ed. 1999;1981-2020 McGraw Hill, New York.
-
(1999)
The Molecular and Metabolic Basis of Inhibited Disease 7th Ed.
, pp. 1981-2020
-
-
Goldstein, J.L.1
Hobbs, H.H.2
Brown, M.S.3
-
3
-
-
0029924138
-
Role of cholesterol in regulating apolipoprotein B secretion by the liver
-
Thompson G.R., Naoumova R.P., Watts G.F. Role of cholesterol in regulating apolipoprotein B secretion by the liver. J. Lipid Res. 37:1996;439-447.
-
(1996)
J. Lipid Res.
, vol.37
, pp. 439-447
-
-
Thompson, G.R.1
Naoumova, R.P.2
Watts, G.F.3
-
4
-
-
0033955791
-
Governance of the concentration of plasma LDL: A reevaluation of the LDL receptor paradigm
-
Sniderman A.D., Zhang X.-J., Cianflone K. Governance of the concentration of plasma LDL: a reevaluation of the LDL receptor paradigm. Atherosclerosis. 148:2000;215-229.
-
(2000)
Atherosclerosis
, vol.148
, pp. 215-229
-
-
Sniderman, A.D.1
Zhang, X.-J.2
Cianflone, K.3
-
5
-
-
0027200040
-
Substrate delivery as a determinant of hepatic apoB secretion
-
Sniderman A.D., Cianflone K. Substrate delivery as a determinant of hepatic apoB secretion. Arterioscler. Thromb. 13:1993;629-636.
-
(1993)
Arterioscler. Thromb.
, vol.13
, pp. 629-636
-
-
Sniderman, A.D.1
Cianflone, K.2
-
6
-
-
0027501003
-
Role of the liver in maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans
-
Dietschy J.M., Turley S.D., Spady D.K. Role of the liver in maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans. J. Lipid Res. 34:1993;1637-1659.
-
(1993)
J. Lipid Res.
, vol.34
, pp. 1637-1659
-
-
Dietschy, J.M.1
Turley, S.D.2
Spady, D.K.3
-
7
-
-
0027258140
-
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
-
Ishibashi S., Brown M.S., Goldstein J.L., Gerard R.D., Hammer R.E., Herz J. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J. Clin. Invest. 92:1993;883-893.
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 883-893
-
-
Ishibashi, S.1
Brown, M.S.2
Goldstein, J.L.3
Gerard, R.D.4
Hammer, R.E.5
Herz, J.6
-
8
-
-
0032900336
-
Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL
-
Horton J.D., Shimano H., Hamilton R.L., Brown M.S., Goldstein J.L. Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL. J. Clin. Invest. 103:1999;1067-1076.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1067-1076
-
-
Horton, J.D.1
Shimano, H.2
Hamilton, R.L.3
Brown, M.S.4
Goldstein, J.L.5
-
9
-
-
0034003980
-
The role of the LDL receptor in apolipoproteinB secretion
-
Twisk J., Gillian-Daniel D.L., Wang L., Tebon A., Barrett P.H.R., Attie A.D. The role of the LDL receptor in apolipoproteinB secretion. J. Clin. Invest. 105:2000;521-532.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 521-532
-
-
Twisk, J.1
Gillian-Daniel, D.L.2
Wang, L.3
Tebon, A.4
Barrett, P.H.R.5
Attie, A.D.6
-
10
-
-
0021041484
-
Secretion of lipoproteins from the liver of normal and Watanabe heritable hyperlipidemic rabbits
-
Hornick C.A., Kita T., Hamilton R.L., Kane J.P., Havel R.J. Secretion of lipoproteins from the liver of normal and Watanabe heritable hyperlipidemic rabbits. Proc. Natl. Acad. Sci. USA. 80:1983;6096-6100.
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 6096-6100
-
-
Hornick, C.A.1
Kita, T.2
Hamilton, R.L.3
Kane, J.P.4
Havel, R.J.5
-
11
-
-
0022482872
-
Deletion in cysteine-rich region of LDL receptor impedes transport to cell surface in WHHL rabbit
-
Yamamoto T., Bishop R.W., Brown M.S., Goldstein J.L., Russell D.W. Deletion in cysteine-rich region of LDL receptor impedes transport to cell surface in WHHL rabbit. Science. 232:1986;1230-1237.
-
(1986)
Science
, vol.232
, pp. 1230-1237
-
-
Yamamoto, T.1
Bishop, R.W.2
Brown, M.S.3
Goldstein, J.L.4
Russell, D.W.5
-
12
-
-
0018886617
-
Kinetic bases of the primary hyperlipidemias: Studies of apolipoprotein B turnover in genetically defined subjects
-
Janus E.D., Nicoll A.M., Turner P.R., Magill P., Lewis B. Kinetic bases of the primary hyperlipidemias: studies of apolipoprotein B turnover in genetically defined subjects. Eur. J. Clin. Invest. 10:1980;161-172.
-
(1980)
Eur. J. Clin. Invest.
, vol.10
, pp. 161-172
-
-
Janus, E.D.1
Nicoll, A.M.2
Turner, P.R.3
Magill, P.4
Lewis, B.5
-
13
-
-
0028179072
-
ApoB metabolism in familial hypercholesterolemia. Inconsistencies with the LDL receptor paradigm
-
Fisher W.R., Zech L.A., Stacpoole P.W. ApoB metabolism in familial hypercholesterolemia. Inconsistencies with the LDL receptor paradigm. Arterioscler. Thromb. 14:1994;501-510.
-
(1994)
Arterioscler. Thromb.
, vol.14
, pp. 501-510
-
-
Fisher, W.R.1
Zech, L.A.2
Stacpoole, P.W.3
-
14
-
-
0028819191
-
Increased hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in heterozygous familial hypercholesterolemia: A stable isotope study
-
Cummings M.H., Watts G.F., Umpleby M., Hennessy T.R., Quiney J.R., Sönksen P.H. Increased hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in heterozygous familial hypercholesterolemia: a stable isotope study. Atherosclerosis. 113:1995;79-89.
-
(1995)
Atherosclerosis
, vol.113
, pp. 79-89
-
-
Cummings, M.H.1
Watts, G.F.2
Umpleby, M.3
Hennessy, T.R.4
Quiney, J.R.5
Sönksen, P.H.6
-
15
-
-
0029098470
-
Simvastatin decreases the hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in heterozygous familial hypercholesterolemia: Pathophysiological and therapeutic implications
-
Watts G.F., Cummings M.H., Umpleby M., Quiney J.R., Naoumova R., Thompson G.R., Sönksen P.H. Simvastatin decreases the hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in heterozygous familial hypercholesterolemia: pathophysiological and therapeutic implications. Eur. J. Clin. Invest. 25:1995;559-567.
-
(1995)
Eur. J. Clin. Invest.
, vol.25
, pp. 559-567
-
-
Watts, G.F.1
Cummings, M.H.2
Umpleby, M.3
Quiney, J.R.4
Naoumova, R.5
Thompson, G.R.6
Sönksen, P.H.7
-
16
-
-
0031951645
-
VLDL and IDL apolipoprotein B-100 kinetics in familial hypercholesterolemia due to impaired LDL receptor function or to defective apolipoprotein B-100
-
Zulewski H., Ninnis R., Miserez A.R., Baumstark M.W., Keller U. VLDL and IDL apolipoprotein B-100 kinetics in familial hypercholesterolemia due to impaired LDL receptor function or to defective apolipoprotein B-100. J. Lipid Res. 39:1998;380-387.
-
(1998)
J. Lipid Res.
, vol.39
, pp. 380-387
-
-
Zulewski, H.1
Ninnis, R.2
Miserez, A.R.3
Baumstark, M.W.4
Keller, U.5
-
17
-
-
0017367180
-
Non-steady-state studies of low-density lipoprotein turnover in familial hypercholesterolemia
-
Thompson G.R., Spinks T., Ranicar A., Myant N.B. Non-steady-state studies of low-density lipoprotein turnover in familial hypercholesterolemia. Clin. Sci. Mol. Med. 52:1977;361-369.
-
(1977)
Clin. Sci. Mol. Med.
, vol.52
, pp. 361-369
-
-
Thompson, G.R.1
Spinks, T.2
Ranicar, A.3
Myant, N.B.4
-
18
-
-
0028061644
-
Acute and chronic effects on cholesterol biosynthesis of LDL-apheresis with or without concomitant HMG-CoA reductase inhibitor therapy
-
Pfohl M., Naoumova R.P., Klass C., Knisel W., Jakober B., Risler T., Thompson G.R. Acute and chronic effects on cholesterol biosynthesis of LDL-apheresis with or without concomitant HMG-CoA reductase inhibitor therapy. J. Lipid Res. 35:1994;1946-1955.
-
(1994)
J. Lipid Res.
, vol.35
, pp. 1946-1955
-
-
Pfohl, M.1
Naoumova, R.P.2
Klass, C.3
Knisel, W.4
Jakober, B.5
Risler, T.6
Thompson, G.R.7
-
19
-
-
0031438512
-
Upregulation of cholesterol synthesis after acute reduction of low density lipoprotein by apheresis in normocholesterolemic subjects: Evidence for a threshold effect
-
Pfohl M., Naoumova R.P., Neuwirth C., Sussekov A., Smykowski J., Rendell N.B., Taylor G.W., Seif F.J., Thompson G.R. Upregulation of cholesterol synthesis after acute reduction of low density lipoprotein by apheresis in normocholesterolemic subjects: evidence for a threshold effect. Atherosclerosis. 135:1997;257-262.
-
(1997)
Atherosclerosis
, vol.135
, pp. 257-262
-
-
Pfohl, M.1
Naoumova, R.P.2
Neuwirth, C.3
Sussekov, A.4
Smykowski, J.5
Rendell, N.B.6
Taylor, G.W.7
Seif, F.J.8
Thompson, G.R.9
-
20
-
-
0030469866
-
Weekly LDL apheresis has no effect on apoB metabolic parameters in heterozygous familial hypercholesterolemia
-
Parhofer K.G., Barrett P.H.R., Demant T., Richter W.O., Schwandt P. Weekly LDL apheresis has no effect on apoB metabolic parameters in heterozygous familial hypercholesterolemia. J. Lipid Res. 37:1996;2383-2393.
-
(1996)
J. Lipid Res.
, vol.37
, pp. 2383-2393
-
-
Parhofer, K.G.1
Barrett, P.H.R.2
Demant, T.3
Richter, W.O.4
Schwandt, P.5
-
21
-
-
13144256792
-
Low-density lipoprotein-apolipoprotein B metabolism following apheresis: Simulation studies of mass changes and tracer kinetics
-
Barrett P.H.R., Parhofer K.G. Low-density lipoprotein-apolipoprotein B metabolism following apheresis: simulation studies of mass changes and tracer kinetics. Metabolism. 47:1998;478-483.
-
(1998)
Metabolism
, vol.47
, pp. 478-483
-
-
Barrett, P.H.R.1
Parhofer, K.G.2
-
22
-
-
0029973954
-
Increased clearance of low density lipoprotein precursors in patients with heterozygous familial defective apolipoprotein B-100: A stable isotope approach
-
Pietzsch J., Wiedemann B., Julius U., Nitzsche S., Gehrisch S., Bergmann S., Leonhardt W., Jaross W., Hanefeld M. Increased clearance of low density lipoprotein precursors in patients with heterozygous familial defective apolipoprotein B-100: a stable isotope approach. J. Lipid Res. 37:1996;2074-2087.
-
(1996)
J. Lipid Res.
, vol.37
, pp. 2074-2087
-
-
Pietzsch, J.1
Wiedemann, B.2
Julius, U.3
Nitzsche, S.4
Gehrisch, S.5
Bergmann, S.6
Leonhardt, W.7
Jaross, W.8
Hanefeld, M.9
-
23
-
-
0031026680
-
Homozygous familial defective apolipoprotein B-100. Enhanced removal of apolipoprotein E-containing VLDLs and decreased production of LDLs
-
Schaefer J.R., Scharnagl H., Baumstark M.W., Schweer H., Zech L.A., Seyberth H., Winkler K., Steinmetz A., März W. Homozygous familial defective apolipoprotein B-100. Enhanced removal of apolipoprotein E-containing VLDLs and decreased production of LDLs. Arterioscler. Thromb. Vasc. Biol. 17:1997;348-353.
-
(1997)
Arterioscler. Thromb. Vasc. Biol.
, vol.17
, pp. 348-353
-
-
Schaefer, J.R.1
Scharnagl, H.2
Baumstark, M.W.3
Schweer, H.4
Zech, L.A.5
Seyberth, H.6
Winkler, K.7
Steinmetz, A.8
März, W.9
-
24
-
-
0030469866
-
Weekly LDL apheresis has no effect on apoB metabolic parameters in heterozygous familial hypercholesterolemia
-
Parhofer K.G., Barrett P.H.R., Demant T., Richter W.O., Schwandt P. Weekly LDL apheresis has no effect on apoB metabolic parameters in heterozygous familial hypercholesterolemia. J. Lipid Res. 37:1996;2383-2393.
-
(1996)
J. Lipid Res.
, vol.37
, pp. 2383-2393
-
-
Parhofer, K.G.1
Barrett, P.H.R.2
Demant, T.3
Richter, W.O.4
Schwandt, P.5
-
25
-
-
0031942101
-
Update on low density lipoprotein receptor mutations
-
Soutar A.K. Update on low density lipoprotein receptor mutations. Curr. Opin. Lipidol. 9:1998;141-147.
-
(1998)
Curr. Opin. Lipidol.
, vol.9
, pp. 141-147
-
-
Soutar, A.K.1
-
26
-
-
0031666905
-
Genotype/phenotype correlations in familial hypercholesterolemia
-
Nicholls P., Young I.S., Graham C.A. Genotype/phenotype correlations in familial hypercholesterolemia. Curr. Opin. Lipidol. 9:1998;313-317.
-
(1998)
Curr. Opin. Lipidol.
, vol.9
, pp. 313-317
-
-
Nicholls, P.1
Young, I.S.2
Graham, C.A.3
-
27
-
-
0028172756
-
Effect on plasma lipid levels of different classes of mutations in the low-density lipoprotein receptor gene in patients with familial hypercholesterolemia
-
Gudnason V., Day I.N., Humpries S.E. Effect on plasma lipid levels of different classes of mutations in the low-density lipoprotein receptor gene in patients with familial hypercholesterolemia. Arterioscler. Thromb. 14:1994;1717-1722.
-
(1994)
Arterioscler. Thromb.
, vol.14
, pp. 1717-1722
-
-
Gudnason, V.1
Day, I.N.2
Humpries, S.E.3
-
28
-
-
0000743072
-
Association of coronary atherosclerosis with hyperapobetalipoproteinemia
-
Sniderman A., Shapiro S., Marpole D., Skinner B., Teng B., Kwiterovich P.O. Jr. Association of coronary atherosclerosis with hyperapobetalipoproteinemia. Proc. Natl. Acad. Sci. USA. 97:1980;604-608.
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 604-608
-
-
Sniderman, A.1
Shapiro, S.2
Marpole, D.3
Skinner, B.4
Teng, B.5
Kwiterovich Jr., P.O.6
-
29
-
-
0025365313
-
Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia
-
Seed M., Hoppichler F., Reaveley D., McCarthy S., Thompson G.R., Boerwinkle E., Utermann G. Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia. New Engl. J. Med. 322:1990;1494-1499.
-
(1990)
New Engl. J. Med.
, vol.322
, pp. 1494-1499
-
-
Seed, M.1
Hoppichler, F.2
Reaveley, D.3
McCarthy, S.4
Thompson, G.R.5
Boerwinkle, E.6
Utermann, G.7
-
30
-
-
0031683495
-
Delayed chylomicron remnant clearance in subjects with heterozygous familial hypercholesterolemia
-
Cabezas M.C., Bruin T.W.A., Westerveld H.E., Meijer E., Erkelens D.W. Delayed chylomicron remnant clearance in subjects with heterozygous familial hypercholesterolemia. J. Intern. Med. 244:1998;299-307.
-
(1998)
J. Intern. Med.
, vol.244
, pp. 299-307
-
-
Cabezas, M.C.1
Bruin, T.W.A.2
Westerveld, H.E.3
Meijer, E.4
Erkelens, D.W.5
-
31
-
-
0023876839
-
HMG-CoA reductase inhibitors for the treatment of hypercholesterolemia
-
Grundy S.M. HMG-CoA reductase inhibitors for the treatment of hypercholesterolemia. New Engl. J. Med. 319:1988;24-33.
-
(1988)
New Engl. J. Med.
, vol.319
, pp. 24-33
-
-
Grundy, S.M.1
|