Regulation of ferritin: A specific role for interferon-alpha (IFN-α)? The acute phase response in patients treated with IFN-α-2b

European Journal of Clinical Investigation

Volumn 32, Issue SUPPL. 1, 2002, Pages 79-83

  Stam, T C ^a   Swaak, A J G ^b,c   Kruit, W H J ^a   Eggermont, A M M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b CENTRAL LABORATORY   (Netherlands)

^c Zuiderziekenhuis   (Netherlands)

Author keywords

Acute phase response; Adult onset Still's disease; Hyperferritinaemia; IFN

Indexed keywords

ACUTE PHASE PROTEIN; ALBUMIN; ALPHA2B INTERFERON; C REACTIVE PROTEIN; FERRITIN; OROSOMUCOID; PHOSPHOLIPASE A2; ALPHA INTERFERON; ANTINEOPLASTIC AGENT; PHOSPHOLIPASE A;

ADJUVANT THERAPY; ARTICLE; CANCER SURGERY; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME BLOOD LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HYPERFERRITINEMIA; JUVENILE RHEUMATOID ARTHRITIS; MELANOMA; NEPHELOMETRY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN SECRETION; PROTEIN SYNTHESIS; ACUTE PHASE RESPONSE; ADULT; ADULT ONSET STILL DISEASE; AGED; BLOOD; CLINICAL TRIAL; FEMALE; IMMUNOLOGY; MALE; METABOLISM; MIDDLE AGED; SKIN TUMOR;

ACUTE-PHASE REACTION; ADULT; AGED; ANTINEOPLASTIC AGENTS; C-REACTIVE PROTEIN; FEMALE; FERRITINS; HUMANS; INTERFERON ALFA-2B; INTERFERON-ALPHA; MALE; MELANOMA; MIDDLE AGED; PHOSPHOLIPASES A; SKIN NEOPLASMS; STILL'S DISEASE, ADULT-ONSET;

EID: 0036512404     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1046/j.1365-2362.2002.0320s1079.x     Document Type: Article

References (26)

1. Knolle P, Lohr H, Treichel U, Dienes HP, Lohse A, Schlaack J, et al. Parenchymal and nonparenchymal liver cells and their interaction in the local immune response. Z Gastroenterol 1995;33:613-20.
2. Kushner I. Regulation of the acute phase response by cytokines. Perspect Biol Med 1993;36:611-22.
3. Baumann H, Gauldie J. The acute phase response. Immunol Today 1994;15:74-80.
4. Koj A. Initiation of acute phase response and synthesis of cytokines. Biochim Biophys Acta 1996;1317:84-94.
5. Swaak AJG, Liénard D, Schraffordt Koops H, Lejeune FJ, Eggermont AMM. Effects of recombinant tumour necrosis factor (rTNF-α) in cancer. Observation on the acute phase protein reaction and immunoglobulin synthesis after high dose recombinant TNF-α administration in isolated limb perfusions in cancer patients. Eur J Clin Invest 1993;23:812-8.
6. Feelders RA, Vreugdenhil G, Eggermont AMM, Kuiper-Kramer PA, van Eijk HG, Swaak AJG. Regulation of iron metabolism in the acute-phase response: interferon gamma and tumour necrosis factor alpha induce hypoferraemia, ferritin production and a decrease in circulating transferrin receptors in cancer patients. Eur J Clin Invest 1998;28:520-7.
7. Banks RE, Forbes MA, Storr M, Higginson J, Thompson D, Raynes J, et al. The acute phase protein response in patients receiving subcutaneous IL-6. Clin Exp Immunol 1995;102:217-23.
8. Stouthard JM, Goey H, de Vries EG, de Mulder PH, Groenewegen A, Pronk L, et al. Recombinant human interleukin 6 in metastatic renal cell cancer: a phase II trial. Br J Cancer 1996;73:789-93.
9. Yamaguchi M, Ohta A, Tsunematsu T, Kasukawa R, Mizushima Y, Kashiwagi H, et al. Preliminary criteria for classification of adult Still's disease. J Rheumatol 1992;19:424-30.
10. Van Reeth C, Le Moel G, Lasne Y, Revenant MC, Agneray J, Kahn MF, Bourgeois P. Serum ferritin and isoferritins are tools for diagnosis of active adult Still's disease. J Rheumatol 1994;21:890-5.
11. Akritidis N, Giannakakis I, Giouglis T. Ferritin levels and response to treatment in patients with Adult Still's disease. J Rheumatol 1996;23:201-2.
12. Akritidis N, Giannakakis Y, Sakkas L. Very high serum ferritin levels in adult-onset Still's disease. Br J Rheumatol 1997;36:608-9.
13. Baynes RD, Bezwoda WR, Bothwell TH, Khan Q, Mansoor N. The non-immune inflammatory response: serial changes in plasma iron, iron-binding capacity, lactoferrin, ferritin and C-reactive protein. Scand J Clin Lab Invest 1986;46:695-704.
14. Van Iperen CE, Kraaijenhagen RJ, Biesma DH, Beguin Y, Marx JJ, Van de Wiel A. Iron metabolism and erythropoiesis after surgery. Br J Surg 1998;85:41-45.
15. Belmonte JA, Ibanez L, Ras MR, Aulesa C, Vinzo J, Iglesias J, et al. Iron metabolism in burned children. Eur J Pediatr 1999;158:556-9.
16. Baynes RD, Bezwoda WR, Dajee D, Lamparelli RD, Bothwell TH. Effects of alpha-interferon on iron-related measurements in human subjects. S Afr Med J 1990;78:627-8.
17. Wolbink GJ, Brouwer MC, Buysmann S, Ten Berge IJM, Hack CE. CRP-mediated activation of complement in vivo. Assessment by measuring circulating complement-C-reactive protein complexes. J Immunol 1996;157:473-9.
18. 2. Cancer Immunol Immunjournal 1995;41:287-92.
19. Kawada E, Shinonome S, Tamura J, Murakami H. Decrease in serum ferritin level in a patient with HCV hepatitis and liver hemosiderosis by interferon-alpha. J Med 1994;25:388-92.
20. Bayraktar Y, Saglam F, Temizer A, Uzunalimodlu B, Van Thiel DH. The effect of interferon and desferrioxamine on serum ferritin and hepatic iron concentrations in chronic hepatitis B. Hepatogastroenterology 1998;45:2322-7.
21. Castro F, Torres EA, Oharriz J, Gonzalez-Keelan C, Perez C, Rubio C. Chronic hepatitis C. treatment comparison between 3 and 5 million units of interferon alpha-2b. P R Health Sci J 1998;17:221-5.
22. Lane HC, Davey V, Kovacs JA, Feinberg J, Metcalf JA, Herpin B, et al. Interferon-alpha in patients with asymptomatic human immunodeficiency virus (HIV) infection. A randomized, placebo-controlled trial. Ann Intern Med 1990;112:805-11.
23. Miller RL, Steis RG, Clark JW, Smith JW 2nd, Crum E, McKnight JE, et al. Randomized trial of recombinant alpha 2b-interferon with or without indomethacin in patients with metastatic malignant melanoma. Cancer Res 1989;49:1871-6.
24. Koeller JM. Biologic response modifiers: the interferon alpha experience. Am J Hosp Pharm 1989;11 (S2):S11-5.
25. Motoo Y, Ohta H, Okai T, Sawabu N. Adult-onset Still's disease: hepatic involvement and various serum markers relating to the disease. Jpn J Med 1991;30:247-50.
26. Esdaile JM, Tannenbaum H, Lough J, Hawkins D. Hepatic abnormalities in adult onset Still's disease. J Rheumatol 1979;6:673-9.