메뉴 건너뛰기




Volumn 73, Issue 6, 1996, Pages 789-793

Recombinant human interleukin 6 in metastatic renal cell cancer: A phase II trial

Author keywords

Human; Interleukin 6; Interleukins; Renal cell cancer

Indexed keywords

ACUTE PHASE PROTEIN; ANTIBODY; BISPHOSPHONIC ACID DERIVATIVE; PARACETAMOL; RECOMBINANT INTERLEUKIN 6;

EID: 9244227559     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.137     Document Type: Article
Times cited : (46)

References (29)
  • 4
    • 0027164803 scopus 로고
    • Interleukin-6 and TNFα production in human renal cell carcinoma
    • GOGUSEV J, AUGUSTI M, CHRÉTIEN Y AND DROZ D. (1993). Interleukin-6 and TNFα production in human renal cell carcinoma. Kidney Int., 44, 585-592.
    • (1993) Kidney Int. , vol.44 , pp. 585-592
    • Gogusev, J.1    Augusti, M.2    Chrétien, Y.3    Droz, D.4
  • 5
    • 0025990509 scopus 로고
    • Interferon-gamma interrupts autocrine growth mediated by endogenous interleukin-6 in renal cell carcinoma
    • GRUSS HJ, BRACH MA, MERTELSMANN RH AND HERRMANN F. (1991). Interferon-gamma interrupts autocrine growth mediated by endogenous interleukin-6 in renal cell carcinoma. Int. J. Cancer, 49, 770-773.
    • (1991) Int. J. Cancer , vol.49 , pp. 770-773
    • Gruss, H.J.1    Brach, M.A.2    Mertelsmann, R.H.3    Herrmann, F.4
  • 6
    • 0026463068 scopus 로고
    • IL-6 and the T-cell response
    • HOUSSIAU F AND VAN SNICK J. (1992). IL-6 and the T-cell response. Res. Immunol., 143, 740-743.
    • (1992) Res. Immunol. , vol.143 , pp. 740-743
    • Houssiau, F.1    Van Snick, J.2
  • 7
    • 0026485357 scopus 로고
    • IL-6 and thrombocytopoiesis
    • ISHIBASHI T AND ASANO S. (1992). IL-6 and thrombocytopoiesis. Res. Immunol., 143, 752-754.
    • (1992) Res. Immunol. , vol.143 , pp. 752-754
    • Ishibashi, T.1    Asano, S.2
  • 8
    • 0024155507 scopus 로고
    • Molecular regulation of B lymphocyte response
    • KISHIMOTO T AND HIRANO T. (1988). Molecular regulation of B lymphocyte response. Ann. Rev. Immunol., 6, 485-512.
    • (1988) Ann. Rev. Immunol. , vol.6 , pp. 485-512
    • Kishimoto, T.1    Hirano, T.2
  • 10
    • 0024814903 scopus 로고
    • Biology of disease. Interleukin-6: A multifunctional cytokine regulating immune reactions and the acute phase protein response
    • LE J AND VILCEK J. (1989). Biology of disease. Interleukin-6: a multifunctional cytokine regulating immune reactions and the acute phase protein response. Lab. Invest., 61, 588-602.
    • (1989) Lab. Invest. , vol.61 , pp. 588-602
    • Le, J.1    Vilcek, J.2
  • 14
    • 0026560406 scopus 로고
    • Cellular mechanisms of antitumour activity of recombinant IL-6 in mice
    • MULÉ JJ, CUSTER MC, TRAVIS WD AND ROSENBERG SA. (1992). Cellular mechanisms of antitumour activity of recombinant IL-6 in mice. J. Immunol., 148, 2622-2629.
    • (1992) J. Immunol. , vol.148 , pp. 2622-2629
    • Mulé, J.J.1    Custer, M.C.2    Travis, W.D.3    Rosenberg, S.A.4
  • 15
    • 0026772066 scopus 로고
    • Interleukin-6 gene transfection into Lewis lung carcinoma tumour cells suppresses the malignant phenotype and confers immunotherapeutic competence against parental metastatic cells
    • PORGADOR A, TZEHOVAL E, KATZ A, VADAI E, REVEL M, FELDMAN M AND EIDENBACH L. (1992). Interleukin-6 gene transfection into Lewis lung carcinoma tumour cells suppresses the malignant phenotype and confers immunotherapeutic competence against parental metastatic cells. Cancer Res., 52, 3679-3686.
    • (1992) Cancer Res. , vol.52 , pp. 3679-3686
    • Porgador, A.1    Tzehoval, E.2    Katz, A.3    Vadai, E.4    Revel, M.5    Feldman, M.6    Eidenbach, L.7
  • 16
    • 0028116332 scopus 로고
    • Tumour stimulating effects of recombinant human interleukin-6
    • RAVOET C, DEGRÈVE J AND VANDEWOUDE K. (1994). Tumour stimulating effects of recombinant human interleukin-6. Lancet, 344, 1576-1577.
    • (1994) Lancet , vol.344 , pp. 1576-1577
    • Ravoet, C.1    Degrève, J.2    Vandewoude, K.3
  • 17
    • 0026481070 scopus 로고
    • Growth regulatory functions of IL-6 and antitumour effects
    • REVEL M. (1992). Growth regulatory functions of IL-6 and antitumour effects. Res. Immunol., 143, 769-773.
    • (1992) Res. Immunol. , vol.143 , pp. 769-773
    • Revel, M.1
  • 18
    • 0023491187 scopus 로고
    • How large should a phase II trial of a new drug be?
    • SIMON R. (1987). How large should a phase II trial of a new drug be? Cancer Treat. Rep., 71, 1079-1085.
    • (1987) Cancer Treat. Rep. , vol.71 , pp. 1079-1085
    • Simon, R.1
  • 19
    • 0026468475 scopus 로고
    • Serum interleukin-6 levels in metastatic renal cell carcinoma: Correlation with survival but not an independent prognostic indicator
    • STADLER WM, RICHARDS JM AND VOGELZANG NJ. (1992). Serum interleukin-6 levels in metastatic renal cell carcinoma: correlation with survival but not an independent prognostic indicator. J. Natl Cancer Inst., 84, 1835-1836.
    • (1992) J. Natl Cancer Inst. , vol.84 , pp. 1835-1836
    • Stadler, W.M.1    Richards, J.M.2    Vogelzang, N.J.3
  • 22
    • 0025779994 scopus 로고
    • Induction of tolerance allows separation of lethal and anti-tumor activities of tumor necrosis factor in mice
    • TAKAHASHI N, BROUCKAERT P AND FIERS W. (1991). Induction of tolerance allows separation of lethal and anti-tumor activities of tumor necrosis factor in mice. Cancer Res., 51, 2366-2372.
    • (1991) Cancer Res. , vol.51 , pp. 2366-2372
    • Takahashi, N.1    Brouckaert, P.2    Fiers, W.3
  • 27
    • 0011151536 scopus 로고
    • A phase II trial of a 120-hour continuous intravenous (CIV) infusion of interleukin-6 (rHuIL-6) for metastatic renal cell carcinoma (RCC)
    • WEISS GR, MARGOLIN KA, SZNOL M, ATKINS MB, OLEKSOWICZ L, ISAACS R AND FISHER RI. (1994). A phase II trial of a 120-hour continuous intravenous (CIV) infusion of interleukin-6 (rHuIL-6) for metastatic renal cell carcinoma (RCC). (abstract). Proc. ASCO, 13, 248.
    • (1994) Proc. ASCO , vol.13 , pp. 248
    • Weiss, G.R.1    Margolin, K.A.2    Sznol, M.3    Atkins, M.B.4    Oleksowicz, L.5    Isaacs, R.6    Fisher, R.I.7
  • 28
    • 0027192081 scopus 로고
    • Immunotherapy for metastatic renal cell carcinoma
    • WIRTH MP. (1993). Immunotherapy for metastatic renal cell carcinoma. Urol. Clin. N. Am., 20, 283-295.
    • (1993) Urol. Clin. N. Am. , vol.20 , pp. 283-295
    • Wirth, M.P.1
  • 29
    • 0027273479 scopus 로고
    • Cytotoxic chemotherapy for advanced renal cell carcinoma
    • YAGODA A, PETRYLAK D AND THOMPSON. (1993). Cytotoxic chemotherapy for advanced renal cell carcinoma. Urol. Clin. N. Am., 20, 303-321.
    • (1993) Urol. Clin. N. Am. , vol.20 , pp. 303-321
    • Yagoda, A.1    Petrylak, D.2    Thompson3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.