Reaction of mouse brain oligodendrocytes and their precursors, astrocytes and microglia, to proinflammatory mediators circulating in the cerebrospinal fluid

GLIA

Volumn 37, Issue 3, 2002, Pages 191-205

  Kong, Guo Ying ^a,c   Kristensson, Krister ^b   Bentivoglio, Marina ^a,c  

^a UNIVERSITY OF VERONA   (Italy)

^b KAROLINSKA INSTITUTE   (Sweden)

^c Faculty of Medicine   (Italy)

Author keywords

Demyelination; Glia; Interferon ; Lipopolysaccharide; Tumor necrosis factor

Indexed keywords

2',3' CYCLIC NUCLEOTIDE 2' PHOSPHODIESTERASE; 2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; 2',3'-CYCLIC NUCLEOTIDE 2'-PHOSPHODIESTERASE; CYTOKINE; DIFFERENTIATION ANTIGEN; GAMMA INTERFERON; GLIAL FIBRILLARY ACIDIC PROTEIN; LIPOPOLYSACCHARIDE; OLIGODENDROCYTE O ANTIGEN, MOUSE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; ASTROCYTE; BRAIN; C57BL MOUSE; CELL COUNT; CEREBROSPINAL FLUID; CHEMICALLY INDUCED DISORDER; CYTOLOGY; DRUG EFFECT; ENCEPHALITIS; GLIOSIS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; MICROGLIA; MOUSE; OLIGODENDROGLIA; PATHOLOGY; STEM CELL; UPREGULATION;

2',3'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES; ANIMALS; ANTIGENS, DIFFERENTIATION; ASTROCYTES; BRAIN; CELL COUNT; CYTOKINES; ENCEPHALITIS; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOSIS; IMMUNOHISTOCHEMISTRY; INTERFERON TYPE II; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MICROGLIA; OLIGODENDROGLIA; STEM CELLS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 0036509709     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/glia.10030     Document Type: Article

References (57)

1. Demonstration of poly-N-acetyl lactosamine residues in ameboid and ramified microglial cells in rat brain by tomato lectin binding
2. Reversible inhibitory effects of interferon-γ, and tumour necrosis factor-α on oligodendroglial lineage cell proliferation and differentiation in vitro
3. Synergistic stimulation of MHC class I and IRF-1 gene expression by IFN-γ and TNF-α in oligodendrocytes
4. Demyelinating diseases
5. TNFα potentiates IFNγ-induced cell death in oligodendrocyte progenitors
6. Developing and mature oligodendrocytes respond differently to the immune cytokine interferon-gamma
7. Reactive astrogliosis in the neonatal mouse brain and its modulation by cytokines
8. Human astrocytes proliferate in response to tumor necrosis factor alpha
9. PDGF and FGF-2 signaling in oligodendrocyte progenitor cells: Regulation of proliferation and differentiation by multiple intracellular signaling pathways
10. Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis
11. Tumour necrosis factor α mRNA expression in early multiple sclerosis lesions: Correlation with demyelinating activity and oligodendrocyte pathology
12. Mechanisms of immune injury in multiple sclerosis
13. Peripheral administration of lipopolysaccharide induces activation of microglial cells in rat brain
14. Proliferation and phenotype regulation in the subventricular zone during experimental allergic encephalomyelitis: In vivo evidence of a role for nerve growth factor
15. Maturation of oligodendrocytes is more sensitive to TNFα than is survival of precursors and immature oligodendrocytes
16. Effects of TNFα on immature and mature oligodendrocytes and their progenitors in vitro
17. NG2-expressing cells in the central nervous system: Are they oligodendroglial progenitors?
18. Molecular profile of reactive astrocytes: Implications for their role in neurologic disease
19. Oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells derived from adult rat spinal cord: In vitro characteristics and response to PDGF, bFGF and NT-3
20. Microglia: Intrinsic immuneffector cell of the brain
21. Endogenous progenitors remyelinate demyelinated axons in the adult CNS
22. Microglia as mediators of inflammatory and degenerative diseases
23. Activation of microglial and endothelial cells in the rat brain after treatment with interferon-gamma in vivo
24. Glia: Listening and talking to the synapse
25. Primary demyelination in transgenic mice expressing interferon-γ
26. Inducible nitric oxide synthase expression elicited in the mouse brain by inflammatory mediators circulating in the cerebrospinal fluid
27. The oligodendrocyte precursor cell in health and disease
28. The pathobiology of the oligodendrocyte
29. Mature oligodendrocyte apoptosis precedes IGF-1 production and oligodendrocyte progenitor accumulation and differentiation during demyelination/remyelination
30. Microglial and astroglial reactions to inflammatory lesions of experimental autoimmune encephalomyelitis in the rat central nervous system
31. Cytokines regulate the cellular phenotype of developing neural lineage species
32. Microglia as effector cells in brain damage and repair: Focus on prostanoids and nitric oxide
33. The role of tumour necrosis factor α, interleukin 6, interferon-gamma and inducible nitric oxide synthase in the development and pathology of the nervous system
34. Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination
35. Astrocyte responses to CNS injury
36. Role of cytokines in multiple sclerosis and experimental autoimmune encephalomyelitis
37. The adult rat hippocampus contains primordial neural stem cells
38. Distribution and temporal regulation of the immune response in the rat brain to intracerebroventricular injection of interferon-gamma
39. Oligodendroglial response to the immune cytokine interferon gamma
40. Demyelinating diseases
41. Neuroglial activation repertoire in the injured brain: Graded response, molecular mechanisms and cues to physiological function
42. Oligodendroglial progenitors labeled with the O4 antibody persist in the adult rat cerebral cortex in vivo
43. Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis
44. Association between tumor necrosis factor-α and disease progression in patients with multiple sclerosis
45. Reactive microgliosis
46. Nerve growth factor protects oligodendrocytes from tumor necrosis factor-α-induced injury through Akt-mediated signaling mechanisms
47. Regulation of MHC molecules on MBP positive oligodendrocytes in mice by IFN-γ, and TNF-α
48. Interferon-γ-induced oligodendrocyte cell death: Implications for the pathogenesis of multiple sclerosis
49. Interferon-γ-induced changes in synaptic activity and AMPA receptor clustering in hippocampal cultures
50. Platelet-derived growth factor is mitogenic for O-2A adult progenitor cells
51. Cooperation between PDGF and FGF converts slowly dividing O-2Aadult progenitor cells to rapidly dividing cells with characteristics of O- 2Aperinatal progenitor cells
52. Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells
53. Oligodendrocyte survival, loss and birth in lesions of chronic-stage multiple sclerosis
54. Gamma-interferon promotes proliferation of adult human astrocytes in vitro and reactive gliosis in the adult mouse brain in vivo
55. Regulation of cell cycle proteins by TNF-α and TGF-β in cells of oligodendroglial lineage
56. TNF-α induced over-expression of GFAP is associated with MAPKs