Recognition and management of hereditary hemochromatosis

American Family Physician

Volumn 65, Issue 5, 2002, Pages

  Brandhagen, David J ^a,b   Fairbanks, Virgil F ^a,b   Baldus, William ^a,b  

^a MAYO CLINIC COLLEGE OF MEDICINE   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HFE PROTEIN; IRON;

ARTICLE; DIABETES MELLITUS; FEMALE; GENE MUTATION; GENETIC DISORDER; GENETIC LINKAGE; GENETIC SCREENING; HEMOCHROMATOSIS; HUMAN; HYPERPIGMENTATION; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PHLEBOTOMY;

ADULT; FEMALE; HEMOCHROMATOSIS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; LIVER; MALE; MEMBRANE PROTEINS; MIDDLE AGED; PHLEBOTOMY; POLYMERASE CHAIN REACTION; PREVALENCE; REFERENCE VALUES; TRANSFERRIN;

EID: 0036500150     PISSN: 0002838X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Population-based screening for hemochromatosis using phenotypic and DNA testing among employees of health maintenance organizations in Springfield, Missouri
2. The effect of HFE genotypes on measurements of iron overload in patients attending a health appraisal clinic
3. Evolving expression of hereditary hemochromatosis
4. Hereditary hemochromatosis
5. Idiopathic hemochromatosis, an iron storage disease
6. Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis
7. Hereditary hemochromatosis: Presentation and diagnosis in the 1990s
8. Hemochromatosis, iron and septicemia caused by Vibrio vulnificus
9. Liver fibrosis in genetic hemochromatosis. Respective roles of iron and non-iron-related factors in 127 homozygous patients
10. A novel MHC class 1-like gene is mutated in patients with hereditary haemochromatosis
11. A novel mutation of HFE explains the classical phenotype of genetic hemochromatosis in a C282Y heterozygote
12. HFE mutations analysis in 711 hemochromatosis probands: Evidence for S65C implication in mild form of hemochromatosis
13. Two novel nonsense mutations of HFE gene in five unrelated Italian patients with hemochromatosis
14. Two novel missense mutations of the HFE gene (I105T and G93R) and identification of the S56C mutation in Alabama hemochromatosis probands
15. The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22
16. Hereditary hemochromatosis: Gene discovery and its implications for population-based screening
17. Heterogeneity of hemochromatosis in Italy
18. Noninvasive prediction of fibrosis in C282Y homozygous hemochromatosis
19. Update on hereditary hemochromatosis and the HFE gene
20. Points to consider: Ethical, legal, and psychosocial implications of genetic testing in children and adolescents
21. EASL international consensus conference on haemochromatosis
22. Long term results of venesection therapy in idiopathic hemochromatosis
23. Population screening for hemochromatosis
24. Screening for hemochromatosis: A cost-effectiveness study based on 12,258 patients
25. Cost-effectiveness of screening for hereditary hemochromatosis
26. Screening blood donors for hereditary hemochromatosis: Decision analysis model comparing genotyping to phenotyping
27. Screening for hemochromatosis. A public health perspective
28. Hereditary haemochromatosis: To screen or not. Conditions for screening are not yet fulfilled
29. The significance of haemochromatosis gene mutations in the general population: Implications for screening
30. Population screening for hemochromatosis: A comparison of unbound iron-binding capacity, transferrin saturation, and C282Y genotyping in 5,211 voluntary blood donors
31. A population-based study of the clinical expression of the hemochromatosis gene
32. Nonexpressing homozygotes for C282Y hemochromatosis: Minority or majority of cases?