Increased rate of glutathione synthesis from cystine in drug-resistant MCF-7 cells

Biochemical Pharmacology

Volumn 63, Issue 5, 2002, Pages 843-851

  Gamcsik, Michael P ^a   Dubay, George R ^b   Cox, Brandon R ^a  

^a DUKE CANCER INSTITUTE   (United States)

^b DUKE UNIVERSITY   (United States)

Author keywords

Biosythesis; Breast cancer; Drug resistance; Glutathione; Metabolism; Stable isotope

Indexed keywords

4 HYDROPEROXYCYCLOPHOSPHAMIDE; CYSTINE; DOXORUBICIN; ETOPOSIDE; GAMMA GLUTAMYLTRANSFERASE; GLUTAMATE CYSTEINE LIGASE;

ARTICLE; BREAST CARCINOMA; CELL STRAIN MCF 7; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; ISOTOPE LABELING; MASS SPECTROMETRY; METABOLIC RATE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STEADY STATE;

BREAST NEOPLASMS; CYSTINE; DRUG RESISTANCE, NEOPLASM; GAMMA-GLUTAMYLTRANSFERASE; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HUMANS; TUMOR CELLS, CULTURED;

EID: 0036496537     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00931-5     Document Type: Article

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