Type-1 steroid 5α-reductase is functionally active in the hair follicle as evidenced by new selective inhibitors of either type-1 or type-2 human steroid 5α-reductase

Experimental Dermatology

Volumn 11, Issue 1, 2002, Pages 52-58

  Gerst, C ^a   Dalko, M ^a   Pichaud, P ^a   Galey, J B ^a   Buan, B ^a   Bernard, B A ^a  

^a L ORÉAL RECHERCHE   (France)

Author keywords

5 reductase inhibitor; Hair follicle; Indole carboxylic acids

Indexed keywords

ANDROSTANEDIOL; ANDROSTANOLONE; ANDROSTENEDIONE; CARBOXYLIC ACID; CARBOXYLIC ACID DERIVATIVE; EPIANDROSTERONE; FINASTERIDE; INDOLECARBOXYLIC ACID DERIVATIVE; STEROID 5ALPHA REDUCTASE; STEROID 5ALPHA REDUCTASE INHIBITOR; TESTOSTERONE; TYPE 1 STEROID 5ALPHA REDUCTASE; TYPE 2 STEROID 5ALPHA REDUCTASE; UNCLASSIFIED DRUG; ENZYME INHIBITOR; INDOLE DERIVATIVE; ISOENZYME;

ANIMAL CELL; ARTICLE; CELL STRAIN COS7; CONTROLLED STUDY; DOSE RESPONSE; DRUG CLASSIFICATION; DRUG POTENCY; DRUG SELECTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; FEMALE; HAIR FOLLICLE; HUMAN; HUMAN TISSUE; IC 50; IN VITRO STUDY; MOLECULE; NONHUMAN; NORMAL HUMAN; STRUCTURE ACTIVITY RELATION; TESTOSTERONE METABOLISM; VOLUNTEER; ANIMAL; CELL STRAIN COS1; CHEMISTRY; DISSECTION; DRUG ANTAGONISM; ENZYMOLOGY; HAPLORHINI; METABOLISM;

ANIMALS; CARBOXYLIC ACIDS; COS CELLS; DISSECTION; ENZYME INHIBITORS; FEMALE; HAIR FOLLICLE; HAPLORHINI; HUMANS; INDOLES; ISOENZYMES; STRUCTURE-ACTIVITY RELATIONSHIP; TESTOSTERONE; TESTOSTERONE 5-ALPHA-REDUCTASE;

EID: 0036481309     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0625.2002.110106.x     Document Type: Article

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