Neural network simulations of the primate oculomotor system: IV. A distributed bilateral stochastic model of the neural integrator of the vertical saccadic system

Biological Cybernetics

Volumn 86, Issue 2, 2002, Pages 97-109

  Sklavos, S G ^a,b   Moschovakis, A K ^a,b  

^a INSTITUTE OF COMPUTER SCIENCE   (Greece)

^b UNIVERSITY OF CRETE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ARTICLE; ARTIFICIAL NEURAL NETWORK; COMPUTER SIMULATION; CRANIAL NERVE; CYTOLOGY; EFFERENT NERVE; EXTRAOCULAR MUSCLE; INNERVATION; PHYSIOLOGY; PRIMATE; SACCADIC EYE MOVEMENT; STATISTICS;

ANIMALS; COMPUTER SIMULATION; CRANIAL NERVES; NEURAL NETWORKS (COMPUTER); NEURONS, EFFERENT; OCULOMOTOR MUSCLES; PRIMATES; SACCADES; STOCHASTIC PROCESSES;

EID: 0036480007     PISSN: 03401200     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004220100281     Document Type: Article

References (63)

1. Anastasio TJ (1998) Nonuniformity in the linear network model of the oculomotor integrator produces approximately fractional-order dynamics and more realistic neuron behavior. Biol Cybern 79: 377-391
2. Anderson JH (1981) Behavior of the vertical canal VOR in normal and INC-lesioned cats. In: Fuch A, Becker W (eds) Progress in oculomotor research. Elsevier, Amsterdam, pp 395-401
3. Arnold DB, Robinson DA (1991) A learning network model of the neural integrator of the oculomotor system. Biol Cybern 64: 447-454
4. Arnold DB, Robinson DA (1997) The oculomotor integrator: testing of a neural network model. Exp Brain Res 113: 57-74
5. Becker W, Klein HM (1973) Accuracy of saccadic eye movements and maintenance of eccentric eye position in the dark. Vision Res 13: 1021-1034
6. Büttner-Ennever JA, Büttner U (1978) A cell group associated with vertical eye movements in the rostral mesencephalic reticular formation of the monkey. Brain Res 151: 31-47
7. Cannon SC, Robinson DA (1985) An improved neural-network model for the neural integrator of the oculomotor system: more realistic neuron behavior. Biol Cybern 53: 93-108
8. Cannon SC, Robinson DA (1987) Loss of the neural integrator of the oculomotor system from brain stem lesions in monkey. J Neurophysiol 57: 1383-1409
9. Cannon SC, Robinson DA, Shamma S (1983) A proposed neural network for the integrator of the oculomotor system. Biol Cybern 49: 127-136
10. Cheron G, Godaux E (1987) Disabling of the oculomotor neural integrator by kainic acid injections in the prepositus-vestibular complex of the cat. J Physiol 394: 267-290
11. Cheron G, Godaux E, Laune JM, Vanerkelen B (1986) Lesions in the cat prepositus complex: effects on the vestibuloocular reflex and saccades. J Physiol 372: 75-94
12. Chubb MC, Fuchs AF, Scudder CA (1984) Neuron activity in monkey vestibular nuclei during vertical vestibular stimulation and eye movements. J Neurophysiol 52: 724-742
13. Crawford JD, Vilis T (1993) Modularity and parallel processing in the oculomotor integrator. Exp Brain Res 96: 443-456
14. Crawford JD, Cadera W, Vilis T (1991) Generation of torsional and vertical eye position signals by the interstitial nucleus of Cajal. Science 252: 1551-1553
15. Dalezios Y, Scudder CA, Highstein SM, Moschovakis AK (1998) Anatomy and physiology of the primate interstitial nucleus of Cajal. II. Discharge pattern of single efferent fibers. J Neurophysiol 80: 3100-3111
16. Delgado-García JM, Vidal PP, Gomez C, Berthoz A (1989) A neurophysiological study of prepositus hypoglossi neurons projecting to oculomotor and preoculomotor nuclei in the alert cat. Neuroscience 29: 291-307
17. Draye J-P, Cheron G, Libert G, Godaux E (1997) Emergence of clusters in the hidden layer of a dynamic recurrent neural network. Biol Cybern 76: 365-374
18. Escudero M, de la Cruz RR, Delgado-García JM (1992) A physiological study of vestibular and prepositus hypoglossi neurones projecting to the abducens nucleus in the alert cat. J Physiol 458: 539-560
19. Fukushima K (1991) The interstitial nucleus of Cajal in the midbrain reticular formation and vertical eye movement. Neurosci Res 10: 159-187
20. Fukushima K, Fukushima J, Harada C, Ohashi T, Kase M (1990) Neuronal activity related to vertical eye movement in the region of the interstitial nucleus of Cajal in alert cats. Exp Brain Res 79: 43-64
21. Fukushima K, Kaneko CRS, Fuchs AF (1992) The neuronal substrate of integration in the oculomotor system. Prog Neurobiol 39: 609-639
22. Fukushima K, Ohashi T, Fukushima J, Kaneko CRS (1995) Discharge characteristics of vestibular and saccade neurons in the rostral midbrain of alert cats. J Neurophysiol 73: 2129-2143
23. Galiana HL, Outerbridge JS (1984) A bilateral model for central neural pathways in the vestibuloocular reflex. J Neurophysiol 51:210-241
24. Gisbergen JAM van, Robinson DA, Gielen S (1981) A quantitative analysis of generation of sacccadic eye movements by burst neurons. J Neurophysiol 45: 417-442
25. Godaux E, Vanderkelen B (1984) Vestibulo-ocular reflex, optokinetic response and their interactions in the cerebellectomized cat. J Physiol 346: 155-170
26. Helmchen C, Rambold H, Fuhry L, Büttner U (1998) Deficits in vertical and torsional eye movements after uni- and bilateral muscimol inactivation of the interstitial nucleus of Cajal of the alert monkey. Exp Brain Res 119: 436-452
27. Horn A, Wahle P, Helmchen C, Büttner-Ennever J (1999) Glutamate decarboxylase mRNA-expressing premotor neurons in the rostral midbrain of the macaque monkey that control vertical eye movements. In: Elsner N, Eysel U (eds) Proceedings of the 1st Göttingen Conference of the German Neuroscience Society. Thieme, Stuttgart p 227
28. Horn AK, Büttner-Ennever JA (1998) Premotor neurons for vertical eye movements in the rostral mesencephalon of monkey and human: histologic identification by parvalbumin immunostaining. J Comp Neurol 392: 413-427
29. Iwamoto Y, Kitama T, Yoshida K (1990) Vertical eye movement-related secondary vestibular neurons ascending in medial longitudinal fasciculus in cat. I. Firing properties and projection pathways. J Neurophysiol 63: 902-917
30. Kamath Y, Keller EL (1976) A neurological integrator for the oculomotor control system. Math Biosci 30: 341-352
31. Kaneko CRS (1997) Eye movement deficits after ibotenic acid lesions of the nucleus prepositus hypoglossi in monkeys. I. Saccades and fixation. J Neurophysiol 78: 1753-1768
32. Kaneko CRS, Fukushima K (1998) Discharge characteristics of vestibular saccade neurons in alert monkeys. J Neurophysiol 79: 835-847
33. Katz E, Cohen B, deJong JMBV, Büttner-Ennevar J (1991) Commissural contributions to velocity storage and the vestibulo-ocular reflex. Exp Brain Res 87: 505-520
34. Keller EL (1974) Participation of medial pontine reticular formation in eye movement generation in monkey. J Neurophysiol 37: 316-332
35. King WM, Fuchs AF (1979) Reticular control of vertical saccadic eye movements by mesencephalic burst neurons. J Neurophysiol 42: 861-876
36. King WM, Fuchs AF, Magnin M (1981) Vertical eye movement-related responses of neurons in midbrain near interstitial nucleus of Cajal. J Neurophysiol 46: 549-562
37. Kokkoroyannis T, Scudder CA, Highstein SM, Balaban C, Moschovakis AK (1996) The anatomy and physiology of the primate interstitial nucleus of Cajal. I. Efferent projections. J Neurophysiol 75: 725-739
38. Lee DD, Reis BY, Seung HS, Tank DW (1997) Nonlinear network models of the oculomotor integrator. In: Bower JM (ed) Computational neuroscience: trends in research. Plenum, New York
39. Le Taillanter M (1991) The interstitial nucleus of Cajal of the cat. II. Effects of kainic acid lesion on vertical optokinetic nystagmus and after-nystagmus. Arch Ital Biol 129: 87-96
40. Lopez-Barneo J, Darlot C, Berthoz A, Baker R (1982) Neuronal activity in prepositus nucleus correlated with eye movement in the alert cat. J Neurophysiol 47: 329-352
41. Luschei ES, Fuchs AF (1972) Activity of brain stem neurons during eye movements of alert monkeys. J Neurophysiol 35: 445-461
42. McCrea RA, Baker R (1985) Anatomical connections of the nucleus prepositus of the cat. J Comp Neurol 237: 377-407
43. McFarland JL, Fuchs AF (1992) The role of the nucleus prepositus hypoglossi and the adjacent medial vestibular nucleus in the control of horizontal eye movements in the behaving monkey. J Neurophysiol 68: 319-332
44. Moschovakis AK (1994) Neural network simulations of the primate oculomotor system. I. The vertical saccadic burst generator. Biol Cybern 70: 291-302
45. Moschovakis AK (1995) Are laws that govern behavior embedded in the structure of the CNS? The case of Hering's law. Vision Res 35: 3207-3216
46. Moschovakis AK (1997) The neural integrators of the mammalian saccadic system. Front Biosci 2: 552-577
47. Moschovakis AK, Scudder CA, Highstein SM (1990) A morphological basis for Hering's law: projections to extraocular motoneurons. Science 248: 1118-1119
48. Moschovakis AK, Scudder CA, Highstein SM (1991a) Structure of the primate burst generator. I. Medium-lead burst neurons with upward on-directions. J Neurophysiol 65: 203-217
49. Moschovakis AK, Scudder CA, Highstein SM, Warren JD (1991b) Structure of the primate burst generator. II. Medium-lead burst neurons with downward on-directions. J Neurophysiol 65: 218-229
50. Optican LM, Robinson DA (1980) Cerebellar-dependent adaptive control of the primate saccadic system. J Neurophysiol 44: 1058-1065
51. Partsalis A, Highstein SM, Moschovakis AK (1994) Lesions of the posterior commissure disable the vertical neural integrator of the primate oculomotor system. J Neurophysiol 71: 2582-2585
52. Ranalli PJ, Sharpe JA, Fletcher WA (1988) Palsy of upward and downward saccadic, pursuit, and vestibular movements with a unilateral midbrain lesion: pathophysiologic correlations. Neurology 38: 114-122
53. Robinson DA (1970) Oculomotor unit behavior in the monkey. J Neurophysiol 33: 393-404
54. Robinson DA (1974) Cerebellectomy and vestibulo-ocular reflex arc. Brain Res 71: 215-224
55. Robinson DA (1981) Control of eye movements. In: Brooks VB (ed) The nervous system Williams and Wilkins, Baltimore, pp 1275-1320
56. Scudder CA, Fuchs AF (1992) Physiological and behavioral identification of vestibular nucleus neurons mediating the horizontal vestibuloocular reflex in trained rhesus monkeys. J Neurophysiol 68: 244-264
57. Seung HS (1996) How the brain keeps the eyes still. Proc Natl Acad Sci USA 93: 13339-13344
58. Sharpe JA, Ranalli PJ (1991) Vertical vestibulo-ocular reflex control after supranuclear midbrain damage. Acta Otolaryngol (Stockh) [Suppl] 481: 194-198
59. Sklavos SG, Moschovakis AK (2000) A new model of the neural integrator of the vertical saccadic system. Eur J Neurosci 12 [Suppl 11]: 163
60. Tomlinson RD, Robinson DA (1984) Signals in vestibular nucleus mediating vertical eye movements in the monkey. J Neurophysiol 51: 1121-1136
61. Vandergraft JS (1978) Introduction to numerical computation. Academic, New York
62. Westheimer G, Blair SM (1974) Functional organization of primate oculomotor system revealed by cerebellectomy. Exp Brain Res 21: 463-475
63. Zee DS, Yamazaki A, Butler PH, Gücer G (1981) Effect of ablation of flocculus and paraflocculus on eye movements in primate. J Neurophysiol 46: 878-899