Screening the monoamine oxidase B gene in 100 male patients with schizophrenia: A cluster of polymorphisms in African-Americans but lack of functionally significant sequence changes

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 74, Issue 1, 1997, Pages 44-49

  Sobell, Janet L ^a  

^a MAYO CLINIC   (United States)

Author keywords

monoamine oxidase; mutations; polymorphism rates; schizophrenia; X chromosome

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING);

ADOLESCENT; ADULT; ARTICLE; GENE LOCATION; GENE MUTATION; GENE SEQUENCE; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NEGRO; PRIORITY JOURNAL; RACE DIFFERENCE; RISK ASSESSMENT; SCHIZOPHRENIA;

AFRICAN CONTINENTAL ANCESTRY GROUP; DNA PRIMERS; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC MARKERS; HUMANS; INDIANS, NORTH AMERICAN; LINKAGE (GENETICS); MALE; MONOAMINE OXIDASE; MUTATION; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; SCHIZOPHRENIA; SEQUENCE ANALYSIS; SEX CHROMOSOMES;

GYMNOMYZA SAMOENSIS;

EID: 0031025838     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19970221)74:1<44::AID-AJMG10>3.0.CO;2-R     Document Type: Article

References (3)

1. American Psychiatric Association (1987): "Diagnostic and Statistical Manual of Mental Disorders, Third Edition." Washington, DC: American Psychiatric Association, 194-195.
2. Bach AWJ, Lan NC, Johnson DL, Abell CW, Bembenek ME, Kwan S, Seeburg PH, Shih JC (1988): cDNA cloning of human liver monoamine oxidase A and B: Molecular basis of differences in enzymatic properties. Proc Natl Acad Sci USA 85:4934-4938.
3. Bottema CDK, Ketterling RP, Ii S, Yoon H, Phillips JA III, Sommer SS (1991): Missense mutations and evolutionary conservation of araino acids: Evidence that many of the amino acids in factor IX function as "spacer" elements. Am J Hum Genet 49:820-838.