Diabetic autonomic neuropathy: Cardiac sympathetic "dysinnervation," QT interval prolongation, and mortality

Clinical Autonomic Research

Volumn 12, Issue 5, 2002, Pages 349-352

  Ziegler, Dan ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

(3 IODOBENZYL)GUANIDINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; EPHEDRINE DERIVATIVE;

AUTONOMIC DYSFUNCTION; AUTONOMIC NERVOUS SYSTEM; CARDIOVASCULAR REFLEX; CARDIOVASCULAR RISK; CONGESTIVE HEART FAILURE; CORONARY ARTERY DISEASE; DIABETIC NEUROPATHY; DISEASE ASSOCIATION; EDITORIAL; EXERCISE TOLERANCE; HEART INFARCTION; HEART INNERVATION; HEART PROTECTION; HEART VENTRICLE TACHYCARDIA; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; ISCHEMIA; MORTALITY; ORTHOSTATIC HYPOTENSION; PROGNOSIS; QT INTERVAL; SYMPATHETIC INNERVATION; SYNCOPE; AUTONOMIC NEUROPATHY; ELECTROCARDIOGRAPHY; NOTE; PATHOPHYSIOLOGY;

AUTONOMIC NERVOUS SYSTEM DISEASES; DIABETIC NEUROPATHIES; ELECTROCARDIOGRAPHY; HUMANS;

EID: 0036460248     PISSN: 09599851     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10286-002-0064-4     Document Type: Editorial

References (30)

1. Ziegler D (1999) Cardiovascular autonomic neuropathy: Clinical manifestations and measurement. Diabetes Rev 7:342-357
2. Gerritsen J, Dekker JM, TenVoorde BJ, Kostense PJ, Heine RJ, Bouter LM, Heethaar RM, Stehouwer CD (2001) Impaired autonomic function is associated with increased mortality, especially in subjects with diabetes, hypertension, or a history of cardiovascular disease: The Hoorn study. Diabetes Care 24:1793-1798
3. Jacobi RM, Nesto RW (1992) Acute myocardial infarction in the diabetic patient: Pathophysiology, clinical course and prognosis. J Am Coll Cardiol 20:736-744
4. Whitsel EA, Boyko EJ, Siscovick DS (2000) Reassessing the role of QTc in the diagnosis of autonomic failure among patients with diabetes. A meta-analysis. Diabetes Care 23:241-247
5. Veglio M, Sivieri R, Chinaglia A, Scaglione L, Cavallo-Perin P (2000) QT interval prolongation and mortality in Type 1 diabetic patients. A 5-year cohort prospective study. Diabetes Care 23:1381-1383
6. Rossing P, Breum L, Major-Pedersen A, Sato A, Winding H, Pietersen A, Kastrup J, Parving HH (2001) Prolonged QTc interval predicts mortality in patients with Type 1 diabetes mellitus. Diabet Med 18:199-205
7. Naas AA, Davidson NC, Thompson C, Cummings F, Ogston SA, Jung RT, Newton RW, Struthers AD (1998) QT and QTc dispersion are accurate predictors of cardiac death in newly diagnosed non-insulin dependent diabetes: Cohort study. BMJ 7:316:745-746
8. Pozzati A, Pancaldi LG, Di Pasquale G, Pinelli G, Bugiardini R (1996) Transient sympathovagal imbalance triggers "ischemic" sudden death in patients undergoing electrocardiographic Holter monitoring. J Am Coll Cardiol 27:847-852
9. Fei L, Anderson MH, Katritsis D, Sneddon J, Statters DJ, Malik M, Camm AJ (1994) Decreased heart rate variability in survivors of sudden cardiac death not associated with coronary artery disease. Br Heart J 71:16-21
10. Bikkina M, Alpert MA, Mukerji R, Mulekar M, Cheng B-Y, Mukerji V (1998) Diminished short-term heart rate variability predicts inducible ventricular tachycardia. Chest 113:312-316
11. Algra A, Tijssen JGP, Roelandt JRTC, Pool J, Lubsen J (1993) Heart rate variability from 24-hour electrocardiography and the 2-year risk for sudden death. Circulation 88:180-185
12. Dekker JM, Schouten EG, Klootwijk P, Pool J, Swenne CA, Kromhout D (1997) Heart rate variability from short electrocardiographic recordings predicts mortality from all causes in middle-aged and elderly men. The Zutphen study. Am J Epidemiol 145:899-908
13. Ziegler D, Langen KJ, Weise F (1999) Contribution de l'imagerie scintigraphique à l'étude de l'innervation sympathique. In: Valensi P, Feuvray D, Sachs R-N (eds) Cœur et Diabète. Paris: Éditions Frison-Roche, pp 443-455
14. Schnell O (2001) Cardiac sympathetic innervation and blood flow regulation of the diabetic heart. Diabetes Metab Res Rev 17:243-245
15. Langen K-J, Ziegler D, Weise F, Piolot R, Boy C, Hübinger A, Gries FA, Müller-Gärtner H-W (1997) Evaluation of QT interval length, QT dispersion and myocardial m-iodobenzylguanidine uptake in insulin-dependent diabetic patients with and without autonomic neuropathy. Clin Sci 92:325-333
16. Matsuo S, Takahashi M, Nakamura Y, Kinoshita M (1996) Evaluation of cardiac sympathetic innervation with iodine-123-metaiodobenzylguanidine imaging in silent myocardial ischemia. J Nucl Med 37:712-717
17. Tsuchimochi S, Tamaki N, Tadamura E, Kawamoto M, Fujita T, Yonekura Y, et al. (1995) Age and gender differences in normal myocardial adrenergic neuronal function evaluated by iodine-123-MIBG imaging. J Nucl Med 36:969-974
18. Morozumi T, Kusuoka H, Fukuchi K, Tani A, Uehara T, Matsuda S, Tsujimura E, Ito Y, Hori M, Kamada T, Nishimura T (1997) Myocardial iodine-123-metaiodobenzylguanidine images and autonomic nerve activity in normal subjects. J Nucl Med 38:49-52
19. Mitrani RD, Klein LS, Miles WM, Hackett FK, Burt RW, Wellman HN, Zipes DP (1993) Regional cardiac sympathetic denervation in patients with ventricular tachycardia in the absence of coronary artery disease. J Am Coll Cardiol 22:1344-1353
20. Stevens MJ, Dayanikli F, Raffel DM, Allman KC, Sandford T, Feldman EL, Wieland DM, Corbett J, Schweiger M (1998) Scintigraphic assessment of regionalized defects in myocardial sympathetic innervation and blood flow regulation in diabetic autonomic neuropathy. J Am Coll Cardiol 31:1575-1584
21. Stevens MJ, Raffel DM, Allman KC, Dayanikli F, Ficaro E, Sandford T, Wieland DM, Pfeifer MA, Schweiger M (1998) Cardiac sympathetic dysinnervation in diabetes. Implications for cardiovascular risk. Circulation 98:961-968
22. Schnell O, Muhr D, Weiss M, Dresel S, Haslbeck M, Standl E (1996) Reduced myocardial 123I-metaiodobenzylguanidine uptake in newly diagnosed IDDM patients. Diabetes 45:801-805
23. Nakajo M, Shapiro B, Glowniak J, Sisson JC, Beierwaltes WH (1983) Inverse relationship between cardiac accumulation of meta-I-131 iodobenzylguanidine (I-131-MIBG) and circulating catecholamines in suspected pheochromocytoma. J Nucl Med 24:1127-1134
24. Herman LM, Dai S, Hartman NG, McNeill JH (1994) Meta-iodobenzylguanidine uptake in the hypertensive-diabetic rat heart. A marker for myocardial dysfunction? Can J Physiol Pharmacol 72:1162-1167
25. Ganguly PK, Beamish RE, Dhalla KS, Innes IR, Dhalla NS (1987) Norepinephrine storage, distribution and release in diabetic cardiomyopathy. Am J Physiol 252:E734-E739
26. Neubauer B, Christensen NJ (1976) The noradrenaline, adrenaline and dopamine content in the cardiovascular system in long-term diabetics. Diabetes 25:6-10
27. 123I]metaiodobenzylguanidine scintigraphy: A 4-year prospective study in IDDM patients. Diabetologia 41:443-451
28. Stevens MJ, Raffel DM, Allman KC, Schwaiger M, Wieland DM (1999) Regression and progression of cardiac sympathetic dysinnervation complicating diabetes; an assessment by C-11 hydroxyephedrine and positron emission tomography. Metabolism 48:92-101
29. Schnell O, Muhr D, Dresel S, Weiss M, Haslbeck M, Standl E (1997) Partial restoration of scintigraphically assessed cardiac sympathetic denervation in newly diagnosed patients with insulin-dependent (type 1) diabetes mellitus at one-year follow-up. Diabetic Med 14:57-62
30. Claus D, Meudt O, Rozeik C, Engelmann-Kempe K, Huppert PE, Wietholtz H (2002) Prospective investigation of autonomic cardiac neuropathy in diabetes mellitus. Clin Auton Res 12:373-378