Depressed inotropic response to increased preload in rabbit hearts with left-ventricular dysfunction induced by chronic myocardial infarction

Pflugers Archiv European Journal of Physiology

Volumn 444, Issue 4, 2002, Pages 513-522

  Ng, G Andre ^b,c   Hicks, Martin N ^b   Cobbe, Stuart M ^b   Smith, Godfrey L ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c GLENFIELD HOSPITAL   (United Kingdom)

Author keywords

Frank Starling; Left ventricular dysfunction; Rabbit; Slow response; Working heart

Indexed keywords

SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; HEART; HEART INFARCTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE COMPLIANCE; HEART OUTPUT; HEART PRELOAD; HEART VENTRICLE ENDDIASTOLIC PRESSURE; INOTROPISM; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SYSTOLIC BLOOD PRESSURE;

ANIMALS; BLOOD PRESSURE; CARDIAC OUTPUT; CHRONIC DISEASE; HEART; MALE; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; ORGAN CULTURE TECHNIQUES; RABBITS; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT;

EID: 0036453021     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-002-0848-3     Document Type: Article

References (35)

1. Hibberd MG, Jewell BR (1982) Calcium and length-dependent force production in rat ventricular muscle. J Physiol (Lond) 329:527-540
2. Kentish JC, Ter Keurs HEDJ, Ricciardi L, Bucx JJJ, Noble MIM (1986) Comparison between the sarcomere length-force relations of intact and skinned trabeculae from rat right ventricle. Circ Res 58:755-768
3. Parmley WW, Chuck LH (1973) Length-dependent changes in myocardial contractile state. Am J Physiol 224:1195-1199
4. Allen DG, Nichols CG, Smith GL (1988) The effects of changes in muscle length during diastole on the calcium transient in ferret ventricular muscle. J Physiol (Lond) 406:359-370
5. Tucci PJF, Bregagnollo EA, Spadaro J, Cicogna AC, Ribeiro MCL (1984) Length dependence of activation studied in the isovolumic blood-perfused dog heart. Circ Res 55:59-66
6. Lew WYW (1988) Time-dependent increase in left ventricular contractility following acute volume loading in dog. Circ Res 63:635-647
7. Noble MIM, Drake-Holland AJ (1994) Lack of importance in humans of the slow component of the response of force to an increase in cardiac muscle length. Clin Sci 87:547-551
8. Massie BM (1998) 15 Years of heart failure trails: What have we learned? Lancet 352:29-33
9. Cohn JN, Bristow MR, Chien KR, Colucci WS, Frazier OH, Leinwand LA, Lorell BH, Moss AJ, Sonnenblick EH, Walsh RA, Mockrin SC, Reinlib L (1997) Report of the national heart, lung, and blood institute special emphasis panel on heart failure research. Circulation 4:766-770
10. Hasenfuss G (1998) Animal models of human cardiovascular disease, heart failure and hypertrophy. Cardiovasc Res 39:60-76
11. Davies CH, Harding SE, Poole-Wilson PA (1996) Cellular mechanisms of contractile dysfunction in human heart failure. Eur Heart J 17:189-198
12. Holubarsch C, Ruf T, Goldstein DJ, Ashton RC, Nickl W, Pieske B, Pioch K, Ludemann J, Wiesner S, Hasenfuss G, Posival H, Just H, Burkhoff D (1996) Existence of the Frank-Starling mechanism in the failing human heart: Investigations on the organ, tissue, and sarcomere levels. Circulation 94:683-689
13. Weil J, Eschenhagen T, Hirt S, Magnussen O, Mittmann C, Remmers Y, Scholz H (1998) Preserved Frank-Starling mechanism in human end stage heart failure. Cardiovasc Res 37: 541-548
14. Schwinger RHG, Bohm M, Koch A, Schmidt U, Morano I, Eissner HJ, Uberfuhr P, Reichart B, Erdmann E (1994) The failing human heart is unable to use the Frank-Starling mechanism. Circ Res 74:959-969
15. Komamura K, Shannon RP, Ihara T, Shen YT, Mirsky I, Bishop SP, Vatner SF (1993) Exhaustion of Frank-Starling mechanism in conscious dogs with heart failure. Am J Physiol 265:H1119-1131
16. Mirsky I, Pasipoularides A (1980) Elastic properties of normal and hypertrophied cardiac muscle. Fed Proc 39:156-161
17. Pye MP, Black M, Cobbe SM (1996) Comparison of in vivo and in vitro hemodynamics function in experimental heart failure - Use of echocardiography. Cardiovasc Res 31:873-881
18. Pye MP, Cobbe SM (1996) Arrhythmogenesis in experimental models of heart failure: The role of increased load. Cardiovasc Res 32:248-257
19. 2+ transients recorded from the epicardial surface of isolated hearts from rabbits with heart failure. Cardiovasc Res 37:489-502
20. Hof RP, Takiguchi Y, Nussberger J, Hof A, Klay M, Peters T, Zelis R, Brunner HR (1991) Baroreceptor and atrial naturetic peptide factor concentration correlate with myocardial infarct size and predict early death in rabbits: Implications for drug studies. J Cardiovasc Pharmacol 18:361-368
21. Mahaffey KW, Rya TE, Pennock GD, Morkin E, Goldman S (1995) Left ventricular remodeling in rabbits after myocardial infarction. Circulation 91:794-801
22. 2+ exchange in the infarcted heart. Circ Res 81:1083-1093
23. Burton FL, McPhaden AR, Cobbe SM (2000) Ventricular fibrillation threshold and local dispersion of refractoriness in isolated rabbit hearts with left ventricular dysfunction. Basic Res Cardiol 95:359-367
24. Neely JR, Liebermeister H, Battersby EJ, Morgan HE (1966) Effect of pressure development on oxygen consumption by isolated rat heart. Am J Physiol 212:804-814
25. Downing SW, Savage EB, Streicher JS, Bogen DK, Tyson GS, Edvisson L (1992) The stretched ventricle. J Thorac Cardiovasc Surg 104:996-1005
26. Kentish JC, Ter Keurs HEDJ, Noble MIM, Ricciardi L, Schouten VJA (1983) The relationships between force, [Ca2+] and sarcomere length in skinned trabeculae from rat ventricle. J Physiol (Lond) 345:24-24
27. Allen DG, Kentish JC (1985) The cellular basis of the length-tension relation in cardiac muscle. J Mol Cell Cardiol 17:821-840
28. 2+ in left ventricular myocytes sub-types from rabbits with heart failure. Cardiovasc Res 45:379-409
29. Humphrey SM, Vanderwee MA, Gavin JB (1988) Transmural differences in the postischemic recovery of cardiac energy metabolism. Am J Pathol 131:5-11
30. 2+ concentration after length changes in isolated rat ventricular trabeculae. J Physiol (Lond) 506:431-444
31. Allen DG, Kurihara S (1979) Calcium transients at different muscle lengths in rat ventricular muscle (abstract). J Physiol (Lond) 292:68P-69P
32. Calaghan SC, White E (1999) The role of calcium in the response of cardiac muscle to stretch. Prog Biophys Mol Biol 71:59-90
33. Harding SE, Brown LA, Wynne DG, Davies CH, Poole-Wilson PA (1994) Mechanisms of beta-adrenoreceptor desensitisation in failing human heart. Cardiovasc Res 28:1451-1460
34. 2+-sensitive isoforms in the failing human heart. Circulation 99:384-391
35. Force T, Pombo C, Avruch J, Bonventre JV, Kyriakis JM (1996) Stress-activated protein kinases in cardiovascular disease. Circ Res 78:947-953