Establishment and characterization of a mouse FM3A cell mutant resistant to topoisomerase II-inhibitor NC-190

Cancer Chemotherapy and Pharmacology

Volumn 50, Issue 5, 2002, Pages 367-372

  Samata, Kazunori ^a,b   Yamagishi, Takehiro ^a   Ichihara, Tomoko ^a   Nanaumi, Kayoko ^a   Ikeda, Tomotake ^a   Ikeya, Hisao ^a   Kuraishi, Aiko ^a   Nakaike, Shiro ^a   Kashiwagi, Keiko ^b   Igarashi, Kazuei ^b  

^a TAISHO PHARMACEUTICAL CO LTD   (Japan)

^b CHIBA UNIVERSITY   (Japan)

Author keywords

DNA topoisomerase II inhibitor; FM NC R cells; Mutated DNA topoisomerase II ; NC 190 resistant

Indexed keywords

6 [[2 (DIMETHYLAMINO)ETHYL]CARBAMOYL] 5 HYDROXY 10 METHOXYBENZO[A]PHENAZINE 9 CARBOXYLIC ACID; ADENOSINE TRIPHOSPHATE; CISPLATIN; DNA TOPOISOMERASE INHIBITOR; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; GLYCINE; GLYCOPROTEIN P; GYRASE INHIBITOR; MITOMYCIN C; VINCRISTINE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BINDING SITE; CANCER CELL CULTURE; CELL MUTANT; CONTROLLED STUDY; LIFESPAN; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATE; AMINO ACID SUBSTITUTION; ANIMALS; ANTINEOPLASTIC AGENTS; BINDING SITES; DNA TOPOISOMERASES, TYPE II; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; ENZYME INHIBITORS; ETOPOSIDE; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MUTATION, MISSENSE; NEOPLASM PROTEINS; PHENAZINES; RNA, MESSENGER; RNA, NEOPLASM; TUMOR CELLS, CULTURED;

EID: 0036452596     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-002-0508-5     Document Type: Article

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