Heroin-associated environmental stimuli modulate the expression of inducible nitric oxide synthase in the rat

Psychopharmacology

Volumn 164, Issue 4, 2002, Pages 416-422

  Lysle, Donald T ^a   Ijames, Stephanie G ^a  

^a University of North Carolina at Chapel Hill   (United States)

Author keywords

Conditioning; Diacetylmorphine; Heroin; Lipopolysaccharide; Nitric oxide

Indexed keywords

DIAMORPHINE; ISOENZYME; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONDITIONING; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; GENE EXPRESSION; INFECTION; LIVER; LUNG; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN; STIMULUS; WESTERN BLOTTING;

ANIMALS; ASSOCIATION LEARNING; BLOTTING, WESTERN; CONDITIONING, CLASSICAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEROIN; INJECTIONS, SUBCUTANEOUS; LIPOPOLYSACCHARIDES; MALE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, INBRED LEW; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 0036449484     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-002-1208-x     Document Type: Article

References (59)

1. Abrass CK, O'Connor SW, Scarpace PJ, Abrass IB (1985) Characterization of the beta-adrenergic receptor of the rat peritoneal macrophage. J Immunol 135:1338-1341
2. Albina JE, Henry WL (1991) Suppression of lymphocyte proliferation through the nitric oxide synthesizing pathway. J Surg Res 50:403-409
3. Al-Ramadi BK, Meissler JJ, Huang D, Eisenstein TK (1992) Immunosuppression induced by nitric oxide and its inhibition by interleukin-4. Eur J Immunol 22:2249-2254
4. Appel NM, Kiritsy-Roy JA, Van Loon GR (1986) Mu receptors at discrete hypothalamic and brainstem sites mediate opioid peptide-induced increases in central sympathetic outflow. Brain Res 378:8-20
5. Brown SM, Stimmel B, Taub RN, Kochwa S, Rosenfield RE (1974) Immunologic dysfunction in heroin addicts. Arch Int Med 134:1001-1006
6. Casella AM, Guardiola H, Renaud FL (1991) Inhibition by opioids of phagocytosis in peritoneal macrophages. Neuropeptides 18:35-40
7. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
8. Coussons ME, Dykstra LA, Lysle DT (1992) Pavlovian conditioning of morphine-induced alterations of immune status. J Neuroimmunol 39:219-230
9. Coussons ME, Dykstra LA, Lysle DT (1994a) Pavlovian conditioning of morphine-induced alterations of immune status: Evidence for opioid receptor involvement. J Neuroimmunol 55:135-142
10. Coussons ME, Dykstra LA, Lysle DT (1994b) Pavlovian conditioning of morphine-induced alterations of immune status: Evidence for peripheral β-adrenergic receptor involvement. Brain Behav Immun 8:204-217
11. Donahoe RM, Nicholson JKA, Madden JJ, Donahoe F, Shafer DA, Gordon D, Bokos P, Falek A (1986) Coordinate and independent effects of heroin, cocaine and alcohol abuse on T-cell E-rosette formation and antigenic marker expression. Clin Immunol 41:254-264
12. Eikelboom R, Stewart J (1979) Conditioned temperature effects using morphine as the unconditioned stimulus. Psychopharmacology 61:31-38
13. Eisenstein TK, Huang D, Meissler JJ, Al-Ramadi B (1994) Macrophage nitric oxide mediates immunosuppression in infectious inflammation. Immunobiology 191:493-502
14. Fecho K, Maslonek KA, Dykstra LA, Lysle DT (1996) Assessment of the involvement of central nervous system and peripheral opioid receptors in the immunomodulatory effects of acute morphine treatment in rats. J Pharmacol Exp Ther 276:626-636
15. Fecho K, Nelson CJ, Lysle DT (2000) Phenotypic and functional assessments of immune status in the rat spleen following acute heroin treatment. Immunopharmacology 46:193-207
16. Felten DL, Felten SY, Carlson SL, Olschowka JA, Livnat S (1985) Noradrenergic and peptidergic innervation of lymphoid tissue. J Immunol 135:755s-765s
17. George R, Way EL (1959) The role of the hypothalamus in pituitary-adrenal activation and antidiuresis by morphine. J Pharmacol Exp Ther 125:111-115
18. Gianutsos G, Cohen SD, Carlson G, Heyman R, Salva P, Morrow G, Hite GJ (1986) Alteration of in vivo and in vitro effects of heroin by esterase inhibition. Toxicol Appl Pharmacol 82:14-18
19. Govitrapong P, Suttitum T, Kotchabhakdi N, Uneklabh T (1998) Alterations of immune functions in heroin addicts and heroin withdrawal subjects. J Pharmacol Exp Ther 266:417-423
20. Green SJ, Nacy CA (1993) Antimicrobial and immunopathologic effect of cytokine-induced nitric oxide synthesis. Curr Opin Infect Dis 6:384-396
21. Green SJ, Meltzer MS, Hibbs JB, Nacy CA (1990) Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism. J Immunol 144:278-283
22. Hadden JW, Hadden EM, Middleton E, Jr (1970) Lymphocyte blast transformation. I. Demonstration of adrenergic receptors in human peripheral lymphocytes. Cell Immunol 1:583-595
23. Hussey HH, Katz S (1950) Infections resulting from narcotic addiction: Report of 102 cases. Am J Med 9:186-193
24. Inturrisi CE, Shultz M, Shin S, Umans JG, Angel L, Simon EJ (1983) Evidence from opiate binding studies that heroin acts through its metabolites. Life Sci 33:773-776
25. Iuvone T, Capasso A, D'Acquisto F, Carnuccio R (1995) Opioids inhibit the induction of nitric oxide synthase in J774 macrophages. Biochem Biophys Res Commun 212:975-980
26. James SL, Glaven J (1989) Macrophage cytotoxicity against schistosomula of Schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates. J Immunol 143:4208-4212
27. Jessop JJ, Taplits MS (1991) Effects of high doses of morphine on Con-A induced lymphokine production in vitro. Immunopharmacology 22:175-184
28. Joseph DB, Bidlack JM (1994) The kappa-opioid receptor expressed on the mouse lymphoma cell line R1.1 contains a sulfhydryl group at the binding site. Eur J Pharmacol 267:1-6
29. Lawrence DM, Joseph DB, Bidlack JM (1995) Kappa opioid receptors expressed on three related thymoma cell lines: Differences in receptor-effector coupling. Biochem Pharmacol 49:81-89
30. Liu S, Ian M, Old RW, Barnes PJ, Evans TW (1993) Lipopolysaccharide treatment in-vivo induces widespread tissue expression of inducible nitric oxide synthase mRNA. Biochem Biophys Res Commun 196:1208-1213
31. Liu S, Barnes PJ, Evans TW (1997) Time course and cellular localization of lipopolysaccharide-induced inducible nitric oxide synthase messenger RNA in the rat in vivo. Crit Care Med 25:512-518
32. Louria DB, Hensle T, Rose J (1967) The major medical complication of heroin addiction. Ann Int Med 67:1-27
33. Luttgens WF (1949) Endocarditis in "main line" opium addicts. Arch Int Med 83:653-664
34. Lysle DT, How T (2000) Heroin induced modulation of inducible nitric oxide synthase. Immunopharmacology 46: 181-192
35. Lysle DT, Hoffman KE, Dykstra LA (1996) Evidence for the involvement of the caudal region of the periaqueductal gray in a subset of morphine-induced alterations of immune status. J Pharmacol Exp Ther 277:1533-1540
36. MacMicking JD, Nathan C, Hom G, Chartrain N, Fletcher DS, Trumbauer M, Stevens K, Xie QW, Sokol K, Hutchinson N, Chen H, Mudgett JS (1995) Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 81:641-650
37. McDonough RJ, Madden JJ, Falek A, Shafer DA, Pline M, Gordon D, Bokos P, Kuehnle JC, Mendelson J (1980) Alteration of T and null lymphocyte frequencies in the peripheral blood of human opiate addicts: In vivo evidence for opiate receptor sites on T lymphocytes. J Immunol 125:2539-2543
38. 3H-clonidine binding in membranes prepared from guinea-pig spleen. Clin Exp Pharmacol Physiol 9:77-87
39. Madden JJ, Donahoe RM, Zwemer-Collins J, Shafer DA, Falek A (1987) Binding of naloxone to human T lymphocytes. Biochem Pharmacol 36:4103-4109
40. Mehrishi JN, Mills IH (1983) Opiate receptors on lymphocytes and platelets in man. Clin Immunol 27:240-249
41. Miksic S, Smith N, Numan R, Lai H (1975) Acquisition and extinction of a conditioned hyperthermic response to a tone paired with morphine administration. Neuropsychobiology 1:277-283
42. Nair MPN, Laing TJ, Schwartz SA (1986) Decreased natural and antibody-dependent cellular cytotoxic activities in intravenous drug users. Clin Immunol 38:68-78
43. Nakamura GR, Thornton JI, Noguchi TT (1975) Kinetics of heroin deacetylation in aqueous alkaline solution and in human serum and whole blood. J Chromatogr 110:81-89
44. Novick DM, Ochshorn M, Ghali V, Croxson TS, Mercer WD, Chiorazzi N, Kreek MJ (1989) Natural killer cell activity and lymphocyte subsets in parenteral heroin abusers and long-term methadone maintenance patients. J Pharmacol Exp Ther 250:606-610
45. Ochshorn M, Novick DM, Kreek MJ (1990) In vitro studies of the effects of methadone on natural killer cell activity. Isr J Med Sci 26:421-425
46. Ovadia H, Nitsan P, Abramsky O (1989) Characterization of opiate binding sites on membranes of rat lymphocytes. J Neuroimmunol 21:93-102
47. Pascual DW, Pascual VH, Bost KL, McGhee JR, Oparil S (1992) Nitric oxide mediates immune dysfunction in the spontaneously hypertensive rat. Hypertension 21:185-194
48. Peterson PK, Sharp B, Gekker G, Keane WF (1987) Opioid-mediated suppression of cultured peripheral blood mononuclear cell respiratory burst activity. J Immunol 138:3907-3912
49. Rojavin M, Szabo I, Bussiere JL, Rogers TJ, Adler MW, Eisenstein TK (1993) Morphine treatment in-vitro or in-vivo decreases phagocytic functions of murine macrophages. Life Sci 53:997-1006
50. Schroeder BE, Holahan MR, Landry CF, Kelley AE (2000) Morphine-associated environmental cues elicit conditioned gene expression. Synapse 37:146-158
51. Schwarz KS, Cunningham CL (1990) Conditioned stimulus control of morphine hyperthermia. Psychopharmacology 101:77-84
52. Sell LA, Morris JS, Bearn J, Frackowiak RSJ, Friston KJ, Dolan RJ (2000) Neural responses associated with cue evoked emotional states and heroin in opiate addicts. Drug Alcohol Depend 60:207-216
53. Shavit Y, DePaulis A, Martin FC, Terman GW, Pechnick RN, Zane CJ, Gale RP, Liebeskind JC (1986) Involvement of brain opiate receptors in the immune-suppressive effect of morphine. Proc Natl Acad Sci USA 83:7114-7117
54. Vincendeau P, Daulouede S, Veyret B, Darde ML, Bouteille B, Lemesre JL (1992) Nitric oxide-mediated cytostatic activity on Trypanosoma brucei gambiense and Trypanosoma brucei brucei. Exp Parasitol 75:353-360
55. Way EL, Kemp JW, Young JM, Grasetti DR (1960) The pharmacologic effects of heroin in relationship to its rate of biotransformation. J Pharmacol Exp Ther 129:144-154
56. Weber RJ, Pert A (1989) The periaqueductal gray matter mediates opiate-induced immunosuppression. Science 245:188-190
57. Wei XQ, Charles IG, Smith A, Ure J, Feng GJ, Huang FP, Xu D, Muller W, Mocado S, Liew FY (1995) Altered immune responses in mice lacking inducible nitric oxide synthase. Nature 375:408-411
58. Wikler WA, Pescor FT (1967) Classical conditioning of a morphine abstinence phenomenon, reinforcement of opioid drinking behavior and "relapse" in morphine-addicted rats. Psychopharmacologia 10:255-284
59. Wybran J, Appelboom T, Famey JP, Govaerts A (1979) Suggestive evidence for receptors for morphine and methionine enkephalin on normal human blood T-lymphocytes. J Immunol 123:1068-1070