Excessive degradation of type II collagen in articular cartilage in equine osteochondrosis

Journal of Orthopaedic Research

Volumn 20, Issue 6, 2002, Pages 1282-1289

  Laverty, S ^a   O'Kouneff, S ^b   Ionescu, M ^b   Reiner, A ^b   Pidoux, I ^b   Webber, C ^b   Rossier, Y ^a   Billinghurst, R C ^b,c   Poole, A R ^b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Cartilage; Collagen; Equine; Horse; Joint disease; Osteochondrosis

Indexed keywords

ASSAYS; CARTILAGE; COLLAGEN; TISSUE CULTURE;

PATHOGENESIS;

ORTHOPEDICS;

COLLAGEN TYPE 2; COLLAGENASE; EPITOPE; PROTEOGLYCAN;

ADOLESCENT; ANIMAL TISSUE; ANTIGEN DETECTION; ARTICLE; ARTICULAR CARTILAGE; AUTOPSY; BINDING ASSAY; CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPLANT; FEMALE; HORSE; MALE; NONHUMAN; OSTEOARTHRITIS; OSTEOCHONDROSIS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; TRIPLE HELIX;

ANIMALS; CARTILAGE, ARTICULAR; CELLS, CULTURED; COLLAGEN TYPE II; COLLAGENASES; CULTURE MEDIA; DNA; FEMALE; HORSE DISEASES; HORSES; MALE; OSTEOCHONDRITIS; PROTEIN DENATURATION; PROTEOGLYCANS;

EID: 0036434856     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0736-0266(02)00053-0     Document Type: Article

References (50)

1. Alini M, Matsui Y, Dodge GR, Poole AR. The extracellular matrix of cartilage in the growth plate before and during calcification; changes in composition and degradation of type II collagen. Calcif Tissue Int 1992;50:327-35.
2. Alvarez J, Balbin M, Santos F, Fernandez M, Ferrando S, Lopez JM. Different bone growth rates are associated with changes in the expression pattern of types II and X collagens and collagenase in proximal growth plates of the rat tibia. J Bone Min Res 2000;15:82-94.
3. Billingburst RC, Dahlberg L, Ionescu M, Reiner A, Bourne R, Rorabeck C, et al. Enhanced cleavage of type II colagen by collagenases in osteoarthritic articular cartilage. J Clin Invest 1997;99:1534-45.
4. Billinghurst RC, Ionescu M, Poole AR. Immunoassay for collagenase-mediated cleavage of types I and II collagens. Method Mol Biol 2001;151:457-72.
5. Billinghurst RC, Wu W, Ionescu M, Reiner A, Dahlberg L, Chen J, et al. Comparison of the degradation of type II collagen and proteoglycan in nasal and articular cartilages induced by interleukin-1 and the selective inhibition of type II collagen cleavage by collagenase. Arth Rheum 2000;43(3):664-72.
6. Bridges CH, Harris ED. Experimentally induced cartilaginous fractures (osteochondritis dissecans) in foals fed low-copper diets. J Am Vet Med Assoc 1988;193:215-21.
7. Campbell CJ, Ranawat CS. Osteochondritis dissecans: the question of etiology. J Trauma 1966;6(2):201-21.
8. Carlson CS, Cullins LD, Meuten DJ. Osteochondrosis of the articular-epiphyseal cartilage complex in young horses: evidence for a defect in cartilage canal blood supply. Vet Pathol 1995;32:641-7.
9. Dahlberg L, Billinghurst RC, Manner P, Nelson F, Webb G, Ionescu M, et al. Selective enhancement of collagenase-mediated cleavage of' resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1). Arth Rheum 2000;43(3):673-83.
10. Ekman S, Carlson CS. The pathophysiology of osteochondrosis. Vet Clin North Am: Small Animal Practice 1998;28:17-32.
11. Farndale R, Buttle DJ, Barret AJ. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethlene blue. Biochent Biophys Acta 1986;88:173-7.
12. Foland J, McIlwraith C, Trotter G. Arthroscopic surgery for osteochondritis dissecans of the femoropatellar joint of the horse. Equine Vet J 1992;24(6):419-23.
13. Freemont AJ, Hampson V, Tilman R, Goupille P, Taiwo Y, Hoyland JA. Gene expression of matrix metalloproteinases 1, 3, and 9 by chondrocytes in osteoarthritic human knee articular cartilage is zone and grade specific. Ann Rheum Dis 1997;56:542-9.
14. Glade MJ, Belling TH. A dietary etiology for osteochondrotic cartilage. J Eq Vet Sci 1986;6(3):151-5.
15. Hollander AP, Heathfield TF, Webber C, Iwata Y, Bourne R, Rorabeck C, et al. Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay. J Clin Invest 1994;93:1722-32.
16. Hollander AP, Pidoux I, Reiner A, Rorabeck C, Poole AR. Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration. J Clin Invest 1995;96:2859-69.
17. Hurtig M, Green SL, Dobson H, Mikuni-Takagaki Y, Choi J. Correlative study of defective cartilage and bone growth in foals fed a low-copper diet. Equine Vet J Suppl 1993;16:66-73.
18. Hurtig MB, Pool RR. Pathogenesis of equine osteochondrosis. In: Mc Ilwraith WC, Trotter GW, editors. Joint disease in the horse. Philadelphia: W.B. Saunders Company; 1996. p. 335-58.
19. Jeffeott LB, Henson FMD. Studies on growth cartilage in the horse and their application to the aetiopathogenesis of dyschondroplasia (osteochondrosis). Vet J 1998;156:177-92.
20. Labarca C, Paigen K. A simple, rapid, and sensitive DNA assay procedure. Anal Biochem 1980;102:344-51.
21. Laverty S, Ionescu M, Marcoux M, Boure L, Doize B, Poole AR. Alterations in cartilage type-II procollagen and aggrecan contents in synovial fluid in equine osteochondrosis. J Orthop Res 2000;18(3):399-405.
22. Lillich JD, Bertone AL, Malemud CJ, Weisbrode SE, Ruggles AJ, Stevenson SS. Biochemical, histochemical and immunochemical characterization of distal tibial osteochondrosis in horses. Am J Vet Res 1997;58:89-98.
23. Lohmander L, Ionescu M, Jugessur H, Poole A. Changes in joint cartilage aggrecan after knee injury and in osteoarthritis. Arth Rheum 1999;42:534-44.
24. Mc Ilwraith WC. Clinical aspects of osteochondritis dissecans. In: Mc Ilwraith WC, Trotter GW, editors. Joint disease in the horse. Philadelphia: W.B. Saunders Company; 1996. p. 362-83.
25. Mitchell PG, Magna HA, Reeves LM, Lopresti-Morrow LL, Yocum SA, Rosner PJ, et al. Cloning, expression and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage. J Clin Invest 1996;97(3):761-8.
26. Mwale F, Billinghurst C, Wu W, Alini M, Webber C, Reiner A, et al. Selective assembly and remodelling of collagens II and IX associated with expression of the chondrocyte hypertrophic phenotype. Dev Dyn 2000;218(4):648-62.
27. Mwale F, Tchetina E, Wu WC, Poole AR. The assembly and remodeling of the extracellular matrix in the growth in relationship to mineral deposition and cellular hypertrophy: an in situ study of collagens II and IX and Proteoglycan. J Bone Jt Surg 2002;17(2):275-83.
28. Nelson F, Dahlberg L, Laverty S, Reiner A, Pidoux I, Ionescu M, et al. Evidence for altered synthesis of type II collagen in patients with osteoarthritis. J Clin Invest 1998;102(12):2115-25.
29. Olsson SE. Introduction. Acta Radiol 1978;1(Suppl 358):7-14.
30. Olsson SE, Reiland S. The nature of osteochondrosis in animals. Acta Radiol 1978;(Suppl 358):299-306.
31. Pappas AM. Osteochondrosis dissecans. Clin Orthop Rel Res 1981;158:59-69.
32. Philipsson J, Andreasson E, Sandgren B, Carlsten J. Osteochondrosis in the tarsocrural joint and osteochondral fragments in the fetlock joints in Standardbred trotters. II Heritability. Equine Vet J Suppl 1993;16:38-41.
33. Pinals RS. Traumatic arthritis and allied conditions. In: Koopman W, editor. Arthritis and allied conditions, Vol. 2. Philadelphia: Lippincott Williams & Wilkins; 2000. p. 1971-86.
34. Pool RR. Difficulties in definition of equine osteochondrosis; differentiation of developmental and acquired lesions. Equine Vet J Suppl 1993;16:5-12.
35. Price JS, Till SH, Bickerstaff DR, Bayliss MT, Hollander AP. Degradation of cartilage type II collagen precedes the onset of osteoarthritis following anterior cruciate ligament rupture. Arth Rheum 1999:42(11):2390-8.
36. Ralston S. Hyperglycemia/hyperinsulinemia after feeding a meal of grain to young horses with osteochondritis dissecans (OCD) lesions. Pferdeheilkunde 1996;3:320-2.
37. Rizkalla G, Reiner A, Bogoch E, Poole AR. Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis. Evidence for molecular heterogeneity and extensive molecular changes in disease. J Clin Invest 1992;90:2268-77.
38. Schenk RC, Athanasiou KA, Constantinides G, Gomez E. A biomechanical analysis of articular cartilage of the human elbow and a potential relationship to osteochondritis dissecans. Clin Orthop Rel Res 1994;299:305-12.
39. Shlopov BV, Lie W-R, Mainardi CL, Cole AA, Chubinskaya S, Hasty KA. Osteoarthritic lesions. Involvement of three different collagenases. Arth Rheum 1997;40(11):2065-74.
40. Siffert RS. Classification of the osteochondroses. Clin Orthop Rel Res 1981;158:10-8.
41. Siffert RS. The Osteochondroses. Clin Orthop Rel Res 1981; 158:2-3.
42. Sloet van Oldruitenborgh-oosterbaan MM, Mol JA, Barneveld A. Hormones, growth factors and other plasma variables in relation to osteochondrosis. Equine Vet J 1999;31:45-54.
43. Sokoloff L. Acquired chondronecrosis. Ann Rheum Dis 1990;49:262-4.
44. Stahle-Backdahl M, Sandstedt B, Bruce K, Lindahl A, Jiminez MG, Vega JA, et al. Collagenase-3 (MMP-13) is expressed during human fetal ossification and re-expressed in postnatal bone remodeling and in Rheumatoid Arthritis. Lab Invest 1997;76(5):717-28.
45. Stoop R, van der Kraan PM, Buma P, Hollander AP, Poole AR, van den Berg WB. Denaturation of type II collagen in articular cartilage in experimental murine arthritis. Evidence for collagen degradation in both reversible and irreversible cartilage damage. J Path 1999;188:329-37.
46. Stougaard J. The hereditary factor in osteochondritis dissecans. J Bone Jt Surg 1961;43B(2):256-8.
47. van den Hoogen BM, van de Lest CHA, van Weeren PR, van Golde LMG, Barneveld A. Changes in proteoglycan metabolism in osteochondrotic articular cartilage of growing foals. Equine Vet J 1999;(Suppl 31):38-44.
48. Wardale RJ, Duance VC. Characterisation of articular and growth plate cartilage collagens in porcine osteochondrosis. J Cell Sci 1994;107:47-59.
49. WU CW, Tchetina EV, Mwale F, Hasty K, Pidoux I, Reiner A, et al. Proteolysis involving Matrix Metalloproteases 13 (Collagenase-3) is required for chondrocyte differentiation that is associated with matrix mineralization. J Bone Min Res 2002;17(4):639-51.
50. Wu W, Mwale F, Tchetina E, Kojima T, Yasuda T, Poole AR. Cartilage matrix resorption in skeletogenesis. Novart Found Symp 2001;232:158-66.