메뉴 건너뛰기




Volumn 80, Issue 4, 2002, Pages 445-455

Hepatitis B viral core protein activates the hepatitis b viral enhancer II/pregenomic promoter through the nuclear factor κB binding site

Author keywords

EnII Cp; Hepatitis B viral core protein (HBc); NF B; Transcriptional activation

Indexed keywords

BIOASSAY; ELECTROPHORESIS; PROTEINS;

EID: 0036434804     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o02-133     Document Type: Article
Times cited : (30)

References (42)
  • 1
    • 0025730640 scopus 로고
    • A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
    • Andrews, N.C., and Faller, D.V. 1991. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 19: 2499.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 2499
    • Andrews, N.C.1    Faller, D.V.2
  • 2
    • 0024538208 scopus 로고
    • Hepatitis B virus (HBV) promoters are regulated by the HBV enhancer in a tissue-specific manner
    • Antonucci, T.K., and Rutter, W.J. 1989. Hepatitis B virus (HBV) promoters are regulated by the HBV enhancer in a tissue-specific manner. J. Virol. 63: 579-583.
    • (1989) J. Virol. , vol.63 , pp. 579-583
    • Antonucci, T.K.1    Rutter, W.J.2
  • 4
    • 0031901220 scopus 로고    scopus 로고
    • Naturally occurring mutations define a novel function of the hepatitis B virus core promoter in core protein expression
    • Baumert, T.F., Marrone, A., Vergalla, J., and Liang, T.J. 1998. Naturally occurring mutations define a novel function of the hepatitis B virus core promoter in core protein expression. J. Virol. 72: 6785-6795.
    • (1998) J. Virol. , vol.72 , pp. 6785-6795
    • Baumert, T.F.1    Marrone, A.2    Vergalla, J.3    Liang, T.J.4
  • 5
    • 0030817061 scopus 로고    scopus 로고
    • Inhibition of NF-kappa B activity induces apoptosis in murine hepatocytes
    • Bellas, R.E., FitzGerald, M.J., Fausto, N., and Sonenshein, G.E. 1997. Inhibition of NF-kappa B activity induces apoptosis in murine hepatocytes. Am. J. Pathol. 151: 891-896.
    • (1997) Am. J. Pathol. , vol.151 , pp. 891-896
    • Bellas, R.E.1    FitzGerald, M.J.2    Fausto, N.3    Sonenshein, G.E.4
  • 6
    • 0021488492 scopus 로고
    • Hepatitis B virus transcription in the infected liver
    • Cattaneo, R., Will, H., and Schaller, H. 1984. Hepatitis B virus transcription in the infected liver. EMBO J. 3: 2191-2196.
    • (1984) EMBO J. , vol.3 , pp. 2191-2196
    • Cattaneo, R.1    Will, H.2    Schaller, H.3
  • 7
    • 0028916425 scopus 로고
    • Hepatitis B virus immunopathogenesis
    • Chisari, F.V., and Ferrari, C. 1995. Hepatitis B virus immunopathogenesis. Annu. Rev. Immunol. 13: 29-60.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 29-60
    • Chisari, F.V.1    Ferrari, C.2
  • 8
    • 0000066015 scopus 로고    scopus 로고
    • Interaction of hepatitis B viral X protein and CCAAT/enhancer-binding protein alpha synergistically activates the hepatitis B viral enhancer II/pregenomic promoter
    • Choi, B.H., Park, G.T., and Rho, H.M. 1999. Interaction of hepatitis B viral X protein and CCAAT/enhancer-binding protein alpha synergistically activates the hepatitis B viral enhancer II/pregenomic promoter. J. Biol. Chem. 274: 2858-2865.
    • (1999) J. Biol. Chem. , vol.274 , pp. 2858-2865
    • Choi, B.H.1    Park, G.T.2    Rho, H.M.3
  • 9
    • 0030013134 scopus 로고    scopus 로고
    • A positive regulatory sequence of hepatitis B viral small X promoter
    • Choi, C.Y., Park, G.T., and Rho, H.M. 1996. A positive regulatory sequence of hepatitis B viral small X promoter. Eur. J. Biochem. 239: 579-587.
    • (1996) Eur. J. Biochem. , vol.239 , pp. 579-587
    • Choi, C.Y.1    Park, G.T.2    Rho, H.M.3
  • 10
    • 0029147911 scopus 로고
    • The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors
    • Doria, M., Klein, N., Lucito, R., and Schneider, R.J. 1995. The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors. EMBO J. 14: 4747-4757.
    • (1995) EMBO J. , vol.14 , pp. 4747-4757
    • Doria, M.1    Klein, N.2    Lucito, R.3    Schneider, R.J.4
  • 11
    • 0026008004 scopus 로고
    • Hepatitis B virus core antigen has two nuclear localization sequences in the arginine-rich carboxyl terminus
    • Eckhardt, S.G., Milich, D.R., and McLachlan, A. 1991. Hepatitis B virus core antigen has two nuclear localization sequences in the arginine-rich carboxyl terminus. J. Virol. 65: 575-582.
    • (1991) J. Virol. , vol.65 , pp. 575-582
    • Eckhardt, S.G.1    Milich, D.R.2    McLachlan, A.3
  • 12
    • 0023080494 scopus 로고
    • The molecular biology of the hepatitis B viruses
    • Ganem, D., and Varmus, H.E. 1987. The molecular biology of the hepatitis B viruses. Annu. Rev. Biochem. 56: 651-693.
    • (1987) Annu. Rev. Biochem. , vol.56 , pp. 651-693
    • Ganem, D.1    Varmus, H.E.2
  • 13
    • 0020435972 scopus 로고
    • Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells
    • Gorman, C.M., Moffat, L.F., and Howard, B.H. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2: 1044-1051.
    • (1982) Mol. Cell. Biol. , vol.2 , pp. 1044-1051
    • Gorman, C.M.1    Moffat, L.F.2    Howard, B.H.3
  • 14
    • 0026795429 scopus 로고
    • RNA- and DNA-binding activities in hepatitis B virus capsid protein: A model for their roles in viral replication
    • Hatton, T., Zhou, S., and Standring, D.N. 1992. RNA- and DNA-binding activities in hepatitis B virus capsid protein: A model for their roles in viral replication. J. Virol. 66: 5232-5241.
    • (1992) J. Virol. , vol.66 , pp. 5232-5241
    • Hatton, T.1    Zhou, S.2    Standring, D.N.3
  • 15
    • 0030296929 scopus 로고    scopus 로고
    • The hepatitis B virus large surface protein (LHBs) is a transcriptional activator
    • Hildt, E., Saher, G., Bruss, V., and Hofschneider, P.H. 1996. The hepatitis B virus large surface protein (LHBs) is a transcriptional activator. Virology, 225: 235-239.
    • (1996) Virology , vol.225 , pp. 235-239
    • Hildt, E.1    Saher, G.2    Bruss, V.3    Hofschneider, P.H.4
  • 16
    • 0024500106 scopus 로고
    • Liver-specific expression of hepatitis B virus is determined by the combined action of the core gene promoter and the enhancer
    • Honigwachs, J., Faktor, O., Dikstein, R., Shaul, Y., and Laub, O. 1989. Liver-specific expression of hepatitis B virus is determined by the combined action of the core gene promoter and the enhancer. J. Virol. 63: 919-924.
    • (1989) J. Virol. , vol.63 , pp. 919-924
    • Honigwachs, J.1    Faktor, O.2    Dikstein, R.3    Shaul, Y.4    Laub, O.5
  • 18
    • 0028223011 scopus 로고
    • Effect of frameshift mutation in the pre-C region of hepatitis B virus on the X and C genes
    • Kim, S.K., Jang, S.K., and Rho, H.M. 1994. Effect of frameshift mutation in the pre-C region of hepatitis B virus on the X and C genes. J. Gen. Virol. 75: 917-923.
    • (1994) J. Gen. Virol. , vol.75 , pp. 917-923
    • Kim, S.K.1    Jang, S.K.2    Rho, H.M.3
  • 19
    • 0028813109 scopus 로고
    • Phosphorylation and nuclear localization of the hepatitis B virus core protein: Significance of serine in the three repeated SPRRR motifs
    • Liao, W., and Ou, J.H. 1995. Phosphorylation and nuclear localization of the hepatitis B virus core protein: Significance of serine in the three repeated SPRRR motifs. J. Virol. 69: 1025-1029.
    • (1995) J. Virol. , vol.69 , pp. 1025-1029
    • Liao, W.1    Ou, J.H.2
  • 20
    • 0031126792 scopus 로고    scopus 로고
    • Rel/NF-kappa B and I kappa B factors in oncogenesis
    • Luque, I., and Gelinas, C. 1997. Rel/NF-kappa B and I kappa B factors in oncogenesis. Semin. Cancer Biol. 8: 103-111.
    • (1997) Semin. Cancer Biol. , vol.8 , pp. 103-111
    • Luque, I.1    Gelinas, C.2
  • 21
    • 0033061215 scopus 로고    scopus 로고
    • Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor alpha-mediated apoptosis via NF-kappaB activation
    • Marusawa, H., Hijikata, M., Chiba, T., and Shimotohno, K. 1999. Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor alpha-mediated apoptosis via NF-kappaB activation. J. Virol. 73: 4713-4720.
    • (1999) J. Virol. , vol.73 , pp. 4713-4720
    • Marusawa, H.1    Hijikata, M.2    Chiba, T.3    Shimotohno, K.4
  • 22
    • 0026623154 scopus 로고
    • Hepatitis B virus transactivator MHBst: Activation of NF-kappa B, selective inhibition by antioxidants and integral membrane localization
    • Meyer, M., Caselmann, W.H., Schluter, V., Schreck, R., Hofschneider, P.H., and Baeuerle, P.A. 1992. Hepatitis B virus transactivator MHBst: Activation of NF-kappa B, selective inhibition by antioxidants and integral membrane localization. EMBO J. 11: 2991-3001.
    • (1992) EMBO J. , vol.11 , pp. 2991-3001
    • Meyer, M.1    Caselmann, W.H.2    Schluter, V.3    Schreck, R.4    Hofschneider, P.H.5    Baeuerle, P.A.6
  • 23
    • 0022628279 scopus 로고
    • Differential distribution of hepatitis B core and E antigens in hepatocytes: Analysis by monoclonal antibodies
    • Mondelli, M., Tedder, R.S., Ferns, B., Pontisso, P., Realdi, G., and Alberti, A. 1986. Differential distribution of hepatitis B core and E antigens in hepatocytes: Analysis by monoclonal antibodies. Hepatology, 6: 199-204.
    • (1986) Hepatology , vol.6 , pp. 199-204
    • Mondelli, M.1    Tedder, R.S.2    Ferns, B.3    Pontisso, P.4    Realdi, G.5    Alberti, A.6
  • 24
    • 0031126817 scopus 로고    scopus 로고
    • The role of Rel/NF-kappa B proteins in viral oncogenesis and the regulation of viral transcription
    • Mosialos, G. 1997. The role of Rel/NF-kappa B proteins in viral oncogenesis and the regulation of viral transcription. Semin. Cancer Biol. 8: 121-129.
    • (1997) Semin. Cancer Biol. , vol.8 , pp. 121-129
    • Mosialos, G.1
  • 25
    • 0031410853 scopus 로고    scopus 로고
    • A negative regulatory element and its binding protein in the upstream of enhancer II of hepatitis B virus
    • Park, G.T., Yi, Y.W., Choi, C.Y., and Rho, H.M. 1997. A negative regulatory element and its binding protein in the upstream of enhancer II of hepatitis B virus. DNA Cell Biol. 16: 1459-1465.
    • (1997) DNA Cell Biol. , vol.16 , pp. 1459-1465
    • Park, G.T.1    Yi, Y.W.2    Choi, C.Y.3    Rho, H.M.4
  • 26
    • 0020363734 scopus 로고
    • The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene
    • Proudfoot, N.J., Gil, A., and Maniatis, T. 1982. The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene. Cell, 31: 553-563.
    • (1982) Cell , vol.31 , pp. 553-563
    • Proudfoot, N.J.1    Gil, A.2    Maniatis, T.3
  • 27
    • 0024517420 scopus 로고
    • The nucleotide sequence and reading frames of a mutant hepatitis B virus subtype adr.
    • Rho, H.M., Kim, K., Hyun, S.W., and Kim, Y.S. 1989. The nucleotide sequence and reading frames of a mutant hepatitis B virus subtype adr. Nucleic Acids Res. 17: 2124.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 2124
    • Rho, H.M.1    Kim, K.2    Hyun, S.W.3    Kim, Y.S.4
  • 28
    • 0025738076 scopus 로고
    • Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65
    • Schmid, R.M., Perkins, N.D., Duckett, C.S., Andrews, P.C., and Nabel, G.J. 1991. Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65. Nature (London), 352: 733-736.
    • (1991) Nature (London) , vol.352 , pp. 733-736
    • Schmid, R.M.1    Perkins, N.D.2    Duckett, C.S.3    Andrews, P.C.4    Nabel, G.J.5
  • 29
    • 0022502287 scopus 로고
    • Biochemical and genetic evidence for the hepatitis B virus replication strategy
    • Seeger, C., Ganem, D., and Varmus, H.E. 1986. Biochemical and genetic evidence for the hepatitis B virus replication strategy. Science (Washington, D.C.), 232: 477-484.
    • (1986) Science (Washington, D.C.) , vol.232 , pp. 477-484
    • Seeger, C.1    Ganem, D.2    Varmus, H.E.3
  • 30
    • 0029019476 scopus 로고
    • Release of the hepatitis B virus-associated DNA polymerase from the viral particle by the proteolytic cleavage
    • Shin, H.J., and Rho, H.M. 1995. Release of the hepatitis B virus-associated DNA polymerase from the viral particle by the proteolytic cleavage. J. Biol. Chem. 270: 11 047-11 050.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11047-11050
    • Shin, H.J.1    Rho, H.M.2
  • 32
    • 0019949367 scopus 로고
    • Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate
    • Summers, J., and Mason, W.S. 1982. Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate. Cell, 29: 403-415.
    • (1982) Cell , vol.29 , pp. 403-415
    • Summers, J.1    Mason, W.S.2
  • 33
    • 0034544619 scopus 로고    scopus 로고
    • Constitutive activation of nuclear factor kappaB in hepatocellular carcinoma
    • Tai, D.I., Tsai, S.L., Chang, Y.H., Huang, S.N., Chen, T.C., Chang, K.S., and Liaw, Y.F. 2000. Constitutive activation of nuclear factor kappaB in hepatocellular carcinoma. Cancer, 89: 2274-2281.
    • (2000) Cancer , vol.89 , pp. 2274-2281
    • Tai, D.I.1    Tsai, S.L.2    Chang, Y.H.3    Huang, S.N.4    Chen, T.C.5    Chang, K.S.6    Liaw, Y.F.7
  • 35
    • 0028971289 scopus 로고
    • Rel/NF-kappa B/I kappa B family: Intimate tales of association and dissociation
    • Verma, I.M., Stevenson, J.K., Schwarz, E.M., Van Antwerp, D., and Miyamoto, S. 1995. Rel/NF-kappa B/I kappa B family: Intimate tales of association and dissociation. Genes Dev. 9: 2723-2735.
    • (1995) Genes Dev. , vol.9 , pp. 2723-2735
    • Verma, I.M.1    Stevenson, J.K.2    Schwarz, E.M.3    Van Antwerp, D.4    Miyamoto, S.5
  • 36
    • 0025279853 scopus 로고
    • A new enhancer element, ENII, identified in the X gene of hepatitis B virus
    • Wang, Y., Chen, P., Wu, X., Sun, A.L., Wang, H., Zhu, Y.A., and Li, Z.P. 1990. A new enhancer element, ENII, identified in the X gene of hepatitis B virus. J. Virol. 64: 3977-3981.
    • (1990) J. Virol. , vol.64 , pp. 3977-3981
    • Wang, Y.1    Chen, P.2    Wu, X.3    Sun, A.L.4    Wang, H.5    Zhu, Y.A.6    Li, Z.P.7
  • 37
    • 0025953943 scopus 로고
    • Identification of the hepatitis B virus factor that inhibits expression of the beta interferon gene
    • Whitten, T.M., Quets, A.T., and Schloemer, R.H. 1991. Identification of the hepatitis B virus factor that inhibits expression of the beta interferon gene. J. Virol. 65: 4699-4704.
    • (1991) J. Virol. , vol.65 , pp. 4699-4704
    • Whitten, T.M.1    Quets, A.T.2    Schloemer, R.H.3
  • 38
    • 0035844148 scopus 로고    scopus 로고
    • Hepatitis C virus core protein activates nuclear factor kappa B-dependent signaling through tumor necrosis factor receptor-associated factor
    • Yoshida, H., Kato, N., Shiratori, Y., Otsuka, M., Maeda, S., Kato, J., and Omata, M. 2001. Hepatitis C virus core protein activates nuclear factor kappa B-dependent signaling through tumor necrosis factor receptor-associated factor. J. Biol. Chem. 276: 16 399-16 405.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16399-16405
    • Yoshida, H.1    Kato, N.2    Shiratori, Y.3    Otsuka, M.4    Maeda, S.5    Kato, J.6    Omata, M.7
  • 39
    • 0032906988 scopus 로고    scopus 로고
    • Hepatitis C virus core protein enhances NF-kappaB signal pathway triggering by lymphotoxin-beta receptor ligand and tumor necrosis factor alpha
    • You, L.R., Chen, C.M., and Lee, Y.H. 1999. Hepatitis C virus core protein enhances NF-kappaB signal pathway triggering by lymphotoxin-beta receptor ligand and tumor necrosis factor alpha. J. Virol. 73: 1672-1681.
    • (1999) J. Virol. , vol.73 , pp. 1672-1681
    • You, L.R.1    Chen, C.M.2    Lee, Y.H.3
  • 40
    • 0030862340 scopus 로고    scopus 로고
    • Differential regulation of the pre-C and pregenomic promoters of human hepatitis B virus by members of the nuclear receptor superfamily
    • Yu, X., and Mertz, J.E. 1997. Differential regulation of the pre-C and pregenomic promoters of human hepatitis B virus by members of the nuclear receptor superfamily. J. Virol. 71: 9366-9374.
    • (1997) J. Virol. , vol.71 , pp. 9366-9374
    • Yu, X.1    Mertz, J.E.2
  • 41
    • 0025182646 scopus 로고
    • The genome of hepatitis B virus contains a second enhancer: Cooperation of two elements within this enhancer is required for its function
    • Yuh, C.H., and Ting, L.P. 1990. The genome of hepatitis B virus contains a second enhancer: cooperation of two elements within this enhancer is required for its function. J. Virol. 64: 4281-4287.
    • (1990) J. Virol. , vol.64 , pp. 4281-4287
    • Yuh, C.H.1    Ting, L.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.