Effect of endothelin-converting enzyme inhibitors on big endothelin-1 induced contraction in isolated rat basilar artery

Acta Neurochirurgica

Volumn 144, Issue 11, 2002, Pages 1213-1219

  Zimmermann, M ^a   Jung, C S ^a   Vatter, H ^a   Raabe, A ^a   Seifert, V ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Big Endothelin 1; Cerebral vasospasm; Endothelin; Endothelin converting enzyme inhibitor

Indexed keywords

BIG ENDOTHELIN 1; BIG ENDOTHELIN 1[22 DEXTRO VALINE]; CAPTOPRIL; ENDOTHELIN CONVERTING ENZYME; ENDOTHELIN CONVERTING ENZYME INHIBITOR; PHOSPHORAMIDON; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BASILAR ARTERY; BIOCHEMISTRY; BRAIN VASOSPASM; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; ENDOTHELIUM; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; INCUBATION TIME; ISOLATION PROCEDURE; MALE; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE; STATISTICAL SIGNIFICANCE; SUBARACHNOID HEMORRHAGE; VASOCONSTRICTION;

ANIMALS; ASPARTIC ENDOPEPTIDASES; BASILAR ARTERY; CAPTOPRIL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIN-1; ENDOTHELINS; ENZYME INHIBITORS; GLYCOPEPTIDES; MALE; METALLOENDOPEPTIDASES; PROTEIN PRECURSORS; RATS; RATS, SPRAGUE-DAWLEY; SUBARACHNOID HEMORRHAGE; VASCULAR RESISTANCE; VASOSPASM, INTRACRANIAL;

EID: 0036434403     PISSN: 00016268     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00701-002-1000-z     Document Type: Article

References (47)

1. Andrews P, Papadakis N, Gavras H (1982) Reversal of experimental acute cerebral vasospasm by angiotensin converting enzyme inhibition. Stroke 13: 480-483
2. Arai H, Hori S, Aramori I, Ohkubo H, Nakanishi S (1990) Cloning and expression of a cDNA encoding an endothelin receptor. Nature 348: 730-732
3. Asano T, Ikegaki I, Satoh S, Suzuki Y, Shibuya M, Sugita K, Hidaka H (1990) Endothelin: A potential modulator of cerebral vasospasm. Eur J Pharmacol 190: 365-372
4. Bax WA, Saxena PR (1994) The current endothelin receptor classification: Time for reconsideration? Trends Pharmacol Sci 15: 379-386
5. Caner HH, Kwan AL, Arthur A, Jeng AY, Lappe RW, Kassell NF, Lee KS (1996) Systemic administration of an inhibitor of endothelin-converting enzyme for attenuation of cerebral vasospasm following experimental subarachnoid hemorrhage. J Neurosurg 85: 917-922
6. Clozel M, Breu V, Burri K, Cassal JM, Fischli W, Gray GA, Hirth G, Loffler BM, Muller M, Neidhart W et al (1993) Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist. Nature 365: 759-761
7. Clozel M, Watanabe H (1993) BQ-123, a peptidic endothelin ETA receptor antagonist, prevents the early cerebral vasospasm following subarachnoid hemorrhage after intracisternal but not intravenous injection. Life Sci 52: 825-834
8. Cosentino F, McMahon EG, Carter JS, Katusic ZS (1993) Effect of endothelinA-receptor antagonist BQ-123 and phosphoramidon on cerebral vasospasm. J Cardiovasc Pharmacol 22: 332-335
9. Ehrenreich H, Schilling L (1995) New developments in the understanding of cerebral vasoregulation and vasospasm: The endothelin-nitric oxide network. Cleve Clin J Med 62: 105-116
10. Emoto N, Yanagisawa M (1995) Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon-sensitive metalloprotease with acidic pH optimum. J Biol Chem 270: 15262-15268
11. Fahnoe DC, Johnson GD, Herman SB, Ahn K (2000) Disulfide bonds in big ET-1 are essential for the specific cleavage at the Trp(21)-Val(22) bond by soluble endothelin converting enzyme-1 from baculovirus/insect cells. Arch Biochem Biophys 373: 385-393
12. Feger GI, Schilling L, Ehrenreich H, Wahl M (1994) Endothelin-induced contraction and relaxation of rat isolated basilar artery: Effect of BQ-123. J Cereb Blood Flow Metab 14: 845-852
13. Fujimori A, Yanagisawa M, Saito A, Goto K, Masaki T, Mima T, Takakura K, Shigeno T (1990) Endothelin in plasma and cerebrospinal fluid of patients with subarachnoid haemorrhage. Lancet 336: 633
14. Fujiwara S, Kassell NF, Sasaki T, Nakagomi T, Lehman RM (1986) Selective hemoglobin inhibition of endothelium-dependent vasodilation of rabbit basilar artery. J Neurosurg 64: 445-452
15. Gavras H, Andrews P, Papadakis N (1981) Reversal of experimental delayed cerebral vasospasm by angiotensin-converting enzyme inhibition. J Neurosurg 55: 884-888
16. Hennington BS, Zhang H, Miller MT, Granger JP, Reckelhoff JF (1998) Angiotensin II stimulates synthesis of endothelial nitric oxide synthase. Hypertension 31: 283-288
17. Honda Y, Minato H, Fujitani B, Masuda Y, Hosoki K (1997) Alacepril, an angiotensin-converting enzyme inhibitor, prevents cerebral vasospasm in subarachnoid hemorrhage model in rats. Methods Find Exp Clin Pharmacol 19: 699-706
18. Hongo K, Kassell NF, Nakagomi T, Sasaki T, Tsukahara T, Ogawa H, Vollmer DG, Lehman RM (1988) Subarachnoid hemorrhage inhibition of endothelium-derived relaxing factor in rabbit basilar artery. J Neurosurg 69: 247-253
19. Ikegawa R, Matsumura Y, Tsukahara Y, Takaoka M, Morimoto S (1990) Phosphoramidon, a metalloproteinase inhibitor, suppresses the secretion of endothelin-1 from cultured endothelial cells by inhibiting a big endothelin-1 converting enzyme. Biochem Biophys Res Commun 171: 669-675
20. Iplikcioglu AC, Bayar MA, Sav A, Erbengi T (1994) Angiotensin-converting enzyme inhibitor cilazapril prevents chronic morphologic vasospasm in rat. Surg Neurol 41: 294-298
21. Kassell NF, Torner JC, Haley EC Jr, Jane JA, Adams HP, Kongable GL (1990) The international cooperative study on the timing of aneurysm surgery. Part 1: Overall management results. J Neurosurg 73: 18-36
22. Kobayashi H, Hayashi M, Kobayashi S, Kabuto M, Handa Y, Kawano H (1990) Effect of endothelin on the canine basilar artery. Neurosurgery 27: 357-361
23. Kukkola PJ, Savage P, Sakane Y, Berry JC, Bilci NA, Ghai RD, Jeng AY (1995) Differential structure-activity relationships of phosphoramidon analogues for inhibition of three metalloproteases: Endothelin-converting enzyme, neutral endopeptidase, and angiotensin-converting enzyme. J Cardiovasc Pharmacol 26: 65-68
24. Matsumura Y, Ikegawa R, Suzuki Y, Takaoka M, Uchida T, Kido H, Shinyama H, Hayashi K, Watanabe M, Morimoto S (1991) Phosphoramidon prevents cerebral vasospasm following subarachnoid hemorrhage in dogs: The relationship to endothelin-1 levels in the cerebrospinal fluid. Life Sci 49: 841-848
25. Matsumura Y, Ikegawa R, Tsukahara Y, Takaoka M, Morimoto S (1991) Conversion of big endothelin-1 to endothelin-1 by two-types of metalloproteinases of cultured porcine vascular smooth muscle cells. Biochem Biophys Res Commun 178: 899-905
26. Matsumura Y, Tsukahara Y, Kuninobu K, Takaoka M, Morimoto S (1992) Phosphoramidon-sensitive endothelin-converting enzyme in vascular endothelial cells converts big endothelin-1 and big endothelin-3 to their mature form. FEBS Lett 305: 86-90
27. Mima T, Yanagisawa M, Shigeno T, Saito A, Goto K, Takakura K, Masaki T (1989) Endothelin acts in feline and canine cerebral arteries from the adventitial side. Stroke 20: 1553-1556
28. Morita A, Nomizu M, Okitsu M, Horie K, Yokogoshi H, Roller PP (1994) D-Val22 containing human big endothelin-1 analog, [D-Val22] Big ET-1 [16-38], inhibits the endothelin converting enzyme. FEBS Lett 353: 84-88
29. Papadopoulos SM, Gilbert LL, Webb RC, D'Amato CJ (1990) Characterization of contractile responses to endothelin in human cerebral arteries: Implications for cerebral vasospasm. Neurosurgery 26: 810-815
30. Parnot C, Le Moullec JM, Cousin MA, Guedin D, Corvol P, Pinet F (1997) A live-cell assay for studying extracellular and intracellular endothelin-converting enzyme activity. Hypertension 30: 837-844
31. Randall MD (1991) Vascular activities of the endothelins. Pharmacol Ther 50: 73-93
32. Saito A, Shiba R, Kimura S, Yanagisawa M, Goto K, Masaki T (1989) Vasoconstrictor response of large cerebral arteries of cats to endothelin, an endothelium-derived vasoactive peptide. Eur J Pharmacol 162: 353-358
33. Saito A, Shiba R, Yanagisawa M, Masaki T, Kimura S, Yamada K, Mima T, Shigeno T, Goto K (1991) Endothelins: Vasoconstrictor effects and localization in canine cerebral arteries. Br J Pharmacol 103: 1129-1135
34. Sakurai T, Yanagisawa M, Takuwa Y, Miyazaki H, Kimura S, Goto K, Masaki T (1990) Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature 348: 732-735
35. Schilling L, Feger GI, Ehrenreich H, Wahl M (1995) Endothelin-1-induced contraction and relaxation of isolated rat basilar artery: Effect of the endothelium. J Cardiovasc Pharmacol 26: 197-199
36. Schilling L, Vatter H, Mursch K, Ehrenreich H, Schmiedek P (2000) Characterization of the contractile and relaxant action of the endothelin-1 precursor, big endothelin-1, in the isolated rat basilar artery. Peptides 21: 91-99
37. Seifert V, Loffler BM, Zimmermann M, Roux S, Stolke D (1995) Endothelin concentrations in patients with aneurysmal subarachnoid hemorrhage. Correlation with cerebral vasospasm, delayed ischemic neurological deficits, and volume of hematoma. J Neurosurg 82: 55-62
38. Suzuki H, Sato S, Suzuki Y, Takekoshi K, Ishihara N, Shimoda S (1990) Increased endothelin concentration in CSF from patients with subarachnoid hemorrhage. Acta Neurol Scand 81: 553-554
39. Turner AJ, Murphy LJ (1996) Molecular pharmacology of endothelin converting enzymes. Biochem Pharmacol 51: 91-102
40. Vatter H, Schilling L, Schmiedek P, Ehrenreich H (1998) Evidence for functional endothelin-converting enzyme activity in isolated rat basilar artery: Effect of inhibitors. J Cardiovasc Pharmacol 31: 64-67
41. Vila JM, Martin de Aguilera E, Irurzun A, Aldasoro M, Flor B, Lluch S (1992) Contractile response of human omental arteries to endothelin. J Pharm Pharmacol 44: 105-108
42. Warner TD, Battistini B, Doherty AM, Corder R (1994) Endothelin receptor antagonists: Actions and rationale for their development. Biochem Pharmacol 48: 625-635
43. Wilson C, Hargreaves RB (1994) Inhibition of the pharmacological effects of endothelin. Prog Med Chem 31: 371-410
44. Xu D, Emoto N, Giaid A, Slaughter C, Kaw S, deWit D, Yanagisawa M (1994) ECE-1: A membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1. Cell 78: 473-485
45. Yanagisawa M, Kurihara H, Kimura S, Goto K, Masaki T (1988) A novel peptide vasoconstrictor, endothelin, is produced by vascular endothelium and modulates smooth muscle Ca2+ channels. J Hypertens [Suppl] 6: 188-191
46. Zimmermann M, Seifert V (1998) Endothelin and subarachnoid hemorrhage: An overview. Neurosurgery 43: 863-875; discussion 875-866
47. Zimmermann M, Seifert V, Loffler BM, Stolke D, Stenzel W (1996) Prevention of cerebral vasospasm after experimental subarachnoid hemorrhage by RO 47-0203, a newly developed orally active endothelin receptor antagonist. Neurosurgery 38: 115-120