Validation of simple indices to assess insulin sensitivity and pancreatic beta-cell function in patients with renal dysfunction

Nephron

Volumn 92, Issue 3, 2002, Pages 713-715

  Kanauchi, Masao ^a   Akai, Yasuhiro ^a   Hashimoto, Toshio ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

Chronic renal failure; Insulin resistance; Insulin sensitivity; Pancreatic beta cell function

Indexed keywords

GLUCOSE; INSULIN;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; CELL ASSAY; CELL FUNCTION; CLINICAL TRIAL; CONCENTRATION (PARAMETERS); CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETES MELLITUS; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HOMEOSTASIS; HUMAN; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; VALIDATION PROCESS;

AGED; BLOOD GLUCOSE; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN RESISTANCE; ISLETS OF LANGERHANS; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS;

EID: 0036424568     PISSN: 00282766     EISSN: None     Source Type: Journal    
DOI: 10.1159/000064072     Document Type: Article

References (10)

1. DeFronzo RA, Alvestrand A, Smith D, Hendler R, Hendler E, Wahren J: Insulin resistance in uremia. J Clin Invest 1981;67:563-568.
2. Schmitz O, Alberti KGMM, Christensen NJ, Hasling C, Hjollund E, Beck-Nielsen H, Orskov H: Aspects of glucose homeostasis in uremia as assessed by the hyperinsulinemic euglycemic clamp technique. Metabolism 1985;34: 465-473.
3. Oshida Y, Sato Y, Shiraishi S, Sakamoto N: Studies on glucose intolerance in chronic renal failure. Clin Nephrol 1987;28:35-38.
4. Alvestrand A, Mujagic M, Wajngot A, Efendic S: Glucose intolerance in uremic patients: The relative contributions of impaired beta-cell function and insulin resitance. Clin Nephrol 1989;31:175-183.
5. Mak RHK, DeFronzo RA: Glucose and insulin metabolism in uremia. Nephron 1992;61:377-382.
6. Matsuda M, DeFronzo R: Insulin sensitivity indices obtained from oral glucose tolerance testing. Diabetes Care 1999;22:1462-1470.
7. Stumvoll M, Mitrakou A, Pimenta W, Jenssen T, Yki-Jarvinen H, Van Haeften T, Renn W, Gerich J: Use of oral glucose tolerance test to assess insulin release and insulin sensitivity. Diabetes Care 2000;23:295-301.
8. Cockcroft DW, Gault MH: Prediction of creatinine clearance from serum creatinine. Nephron 1976;16:31-41.
9. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC: Homeostasis model assessment. Diabetologia 1985;28:412-419
10. Eidemak I, Feldt-Rasmussen B, Kanstrup IL, Nielsen SL, Schmitz O, Strandgaard S: Insulin resistance and hyperinsulinemia in mild to moderate progressive chronic renal failure and its association with aerobic work capacity. Diabetologia 1995;38:565-572.