Effect of antioxidant therapy with dl-α-tocopherol on cardiovascular structure in experimental renal failure

Kidney International

Volumn 62, Issue 3, 2002, Pages 877-884

  Amann, Kerstin ^a,b,c   Törnig, Johannes ^a,b,c   Buzello, Mareike ^a,b,c   Kuhlmann, Alexander ^a,b,c   Gross, Marie Lulse ^a,b,c   Adamczak, Marcin ^a,b,c   Buzello, Moriz ^a,b,c   Ritz, Eberhard ^a,b,c  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

Cardiac capillarization; Left ventricular hypertrophy; Microarteriopathy; Myocardial fibrosis; Oxidative stress; Tocopherol; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AORTA; ARTERIOLE; ARTICLE; BLOOD VESSEL; BODY WEIGHT; CELL DENSITY; CONTROLLED STUDY; DRUG EFFECT; HEART MUSCLE CAPILLARY; HEART MUSCLE CELL; HEART VENTRICLE; HEART WEIGHT; HEMODYNAMIC MONITORING; KIDNEY FAILURE; MALE; MORPHOMETRICS; NEPHRECTOMY; NONHUMAN; PLETHYSMOGRAPHY; PRIORITY JOURNAL; RAT; STEREOLOGY; SURGICAL TECHNIQUE; SYSTOLIC BLOOD PRESSURE; TREATMENT OUTCOME;

EID: 0036423876     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2002.00518.x     Document Type: Article

References (46)

1. European Transplantation and Dialysis Association: Report on Management of Renal Failure in Europe, XXIV, 1993. Nephrol Dial Transplant 10(Suppl 5):12, 1995
2. US Renal Data System: Causes of death, in Annual Data Report (vo114), Bethesda, National Institute of Health, National Institute of Diabetes and Digestive and Kidney Diseases 1995, pp 79-90
3. Parfrey PS, Foley RN, Harnett JD, et al: Outcome and risk factors for left ventricular disorders in chronic uremia. Nephrol Dial Transplant 11:1277-1285, 1996
4. Rostand SG, Kirk KA, Rutsky EA: Dialysis-associated ischemic heart disease: Insights from coronary angiography. Kidney Int 25:653-659, 1984
5. Blacher J, Guerin AP, Pannier B, et al: Impact of aortic stiffness on survival in end-stage renal disease. Circulation 99:2434-2439, 1999
6. Törnig J, Amann K, Ritz E, et al: Arteriolar wall thickening, capillary rarefaction and interstitial fibrosis in the heart of rats with renal failure: The effect of ramipril, nifedipine and moxonidine. J Am Soc Nephrol 7:667-675, 1996
7. Amann K, Brettbach M, Ritz E, Mall G: Myocyte/capillary mismatch in the heart of uremic patients. J Am Soc Nephrol 9:10181022, 1998
8. Amann K, Wiest G, Zimmer G, et al: Reduced capillary density in the myocardium of uremic rats - A stereological study. Kidney Int 42:1079-1085, 1992
9. Lindner A, Charra B, Sherrard D J, Scribner BH: Accelerated atherosclerosis in prolonged maintenance hemodialysis. N Engl J Med 290:697-701, 1974
10. Schwarz U, Buzello M, Ritz E, et al: Morphology of coronary atherosclerotic lesions in patients with end-stage renal failure. Nephrol Dial Transplant 15:218-223, 2000
11. Ritz E, Amann K, To̊rnig J, et al: Some cardiac abnormalities in renal failure, in Advances in Nephrology, edited by GRONFELD JP, BACI-I JF, Km@IS H, et al, St. Louis, Mosby, 1997, pp 85-97
12. Demuth K, Blacher J, Guerin AP, et al: Endothelin and cardiovascular remodelling in end-stage renal disease. Nephrol Dial Transplant 13:375-383, 1998
13. Fiorillo C, Oliviero C, Rizzuti G, et al: Oxidative stress and antioxidant defenses in renal patients receiving regular haemodialysis. Clin Chem Lab Med 36:149-153, 1998
14. Tetta C, Biasioli S, Schiavon R, et al: An overview of haemodialysis and oxidant stress. Blood Purif 17:118-126, 1999
15. Canaud B, Cristol J, Morena M, et al: Imbalance of oxidants and antioxidants in haemodialysis patients. Blood Purif 17:99-106, 1999
16. Galli F, Canestrari F, Buoncristian U: Biological effects of oxidant stress in haemodialysis: The possible roles of vitamin E. Blood Purif 17:79-94, 1999
17. Panzetta O, Cominacini L, Garbin U, et al: Increased susceptibility of LDL to in vitro oxidation in patients on maintenance hemodialysis: Effects of fish oil and vitamin E administration. Clin Nephrol 44:303-309, 1995
18. Zanzinger J, Czachurski J: Chronic oxidative stress in the RVLM modulates sympathetic control of circulation in pigs. Pfitigers Arch 439:489-494, 2000
19. Miyazaki H, Matsuoka H, Itabe H, et al: Hemodialysis impairs endothelial function via oxidative stress: Effects of vitamin E-coated dialyzer. Circulation 101:1002-1006, 2000
20. Wolf G: Free radical production and angiotensin. Curr Hypertens Rep 2:167-173, 2000
21. Mattfeldt T, Mall G, Gharehbaghi H, Möller P: Estimation of surface area and length with the orientator. J Microsc 159:301-317, 1990
22. Rambausek M, Ritz E, Mall G, et al: Myocardial hypertrophy in rats with renal insufficiency. Kidney Int 28:775-782, 1985
23. Weinstein, Mihm MJ, Bauer JA: Cardiac peroxynitrite formation and left ventricular dysfunction following doxorubicin treatment in mice. J Pharmacol Exp Ther 294:396-401, 2000
24. Mihm JM, Coyle CM, Schanbacher BL, et al: Peroxynitrite induced nitration and inactivation of myofibrillar creatine kinase in experimental heart failure. Cardiovasc Res 49:798-807, 2001
25. Amann K, Neirmeier KA, Schwarz U, et al: Rats with moderate renal failure showing capillary deficit in the heart but not in skeletal muscle. Am J Kidney Dis 30:382-388, 1997
26. Amann K, Ritz E: Nephrol Dial Transplant 15:1493-1503, 2000
27. Amann K, Neusoss R, Ritz E, et al: Changes of vascular architecture independent of blood pressure in experimental uremia. Am J Hypertens 8:409-417, 1995
28. Amann K, Monter K, Wagner J, et al: Endothelin A receptor blockade prevents capillary/myocyte mismatch in the heart of uremic animals. J Am Soc Nephrol 11:1702-1711, 2000
29. Nabokov AV, Amann K, Wessels S, et al: Endothelin receptor antagonists influence cardiovascular morphology in uremic rats. Kidney Int 55:512-519, 1999
30. Foley RN, Parfrey PS, Harnett JD, et al: The impact of anemia on cardiomyopathy, morbidity, and mortality in end-stage renal disease. Am J Kidney Dis 28:53-61, 1996
31. Silberberg J, Racine N, Barre P, Sniderman AD: Regression of left ventricular hypertrophy in dialysis patients following correction of anemia with recombinant human erythropoietin. Can J Cardiol 6:1-4, 1990
32. Eckardt KU: Cardiovascular consequences of renal anaemia and erythropoietin therapy. Nephrol Dial Transplant 14:1317-1323, 1999
33. Cristol JP, Bosc JY, Badious S, et al: Erythropoietin and oxidative stress in haemodialysis: Beneficial effects of vitamin E supplementation. Nephrol Dial Transplant 12:2312-2317, 1997
34. Amann K, Buzello M, Simonavlciene A, et al: Capillary/myocyte mismatch in the heart in renal failure - A role for erythropoietin? Nephrol Dial Transplant 15:964-969, 2000
35. Campese VM, Kogosov E, Koss M: Renal afferent denervation prevents the progression of renal disease in the renal ablation model of chronic renal failure in the rat. Am J Kidney Dis 26:861865, 1995
36. Ligtenberg G, Blankestijn P J, Oey PL, et al: Reduction of sympathetic hyperactivity by enalapril in patients with chronic renal failure. N Engl J Med 340:1321-1328, 1999
37. Kojda G, Harrison D: Interactions between NO and reactive oxygen species: Pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure. Cardiovasc Res 43:562571, 1999
38. Ruef J, Peter K, Nordt TK, et al: Oxidative stress and atherosclerosis: Its relationship to growth factors, thrombus formation and therapeutic approaches. Thromb Haemost 82(Suppl 1):32-37, 1999
39. Ogata N, Yamamoto H, Kugiyama K, et al: Involvement of protein kinase C in superoxide anion-induced activation of nuclear factorkappa B in human endothelial cells. Cardiovasc Res 45:513-521, 2000
40. Jenkins AJ, Li W, Moller K, et al: Pre-enrichment of modified low density lipoproteins with alpha-tocopherol mitigates adverse effects on cultured retinal capillary effects on cultured retinal capillary cells. Curr Eye Res 19:137-145, 1999
41. Vendetti P, Masullo P, Di Meo S, Agnisola C: Protection against ischemia-reperfusion induced oxidative stress by vitamin E treatment. Arch Physiol Biochem 107:27-34, 1999
42. Sethi R, Takeda N, Nagano M, Dhalla NS: Beneficial effects of vitamin E treatment in acute myocardial infarction. J Cardiovasc Pharmacol Ther 5:51-58, 2000
43. Hoogwerf BJ, Young JB: The HOPE study. Ramipril lowered cardiovascular risk, but vitamin E did not. Cleve Clin JMed 67:287293, 2000
44. Islam KN, O'Byrne D, Devaraj S, et al: Alpha-tocopherol supplementation decreases the oxidative susceptibility of LDL in renal failure patients on dialysis therapy. Atherosclerosis 150:217-224, 2000
45. Mydlink M, Derzsiova K, Racz O, et al: A modified dialyzer with vitamin E and antioxidant defense parameters. Kidney Int 59(Suppl 78):S144-S147, 2001
46. Boaz M, Smetana S, Weinstein T, et al: Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): Randomised placebo-controlled trial. Lancet 356:12131218, 2000