Synthesis of 4-alkylamino-6-chloroquinolines as potential trypanocidal agents

Heterocyclic Communications

Volumn 8, Issue 4, 2002, Pages 339-342

  Tapia, Ricardo A ^a   Prieto, Yolanda ^a   Valderrama, Jaime A ^a   Fournet, Alain ^a   Rojas de Arias, Antonieta ^a   Nakayama, Héctor ^a   Torres, Susana ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 ETHYLPIPERAZIN 1 YL) 5,8 DIMETHOXY 6 CHLOROQUINOLINE; 4 (4 METHYLPIPERAZIN 1 YL) 5,8 DIMETHOXY 6 CHLOROQUINOLINE; 4 N BUTYLAMINO 5,8 DIMETHOXY 6 CHLOROQUINOLINE; 4 N PIPERIDIN 5,8 DIMETHOXY 6 CHLOROQUINOLINE; 4 N PROPYLAMINO 5,8 DIMETHOXY 6 CHLOROQUINOLINE; 5 [[(2,5 DIMETHOXYPHENYLAMINO)]METHYLIDENE] 2,2 DIMETHYL 4,6 DIOXO 1,3 DIOXANE; 5,8 DIMETHOXY 6 CHLORO 4(1H) QUINOLONE; ACID; ANTITRYPANOSOMAL AGENT; CARBENOID; DIOXANE DERIVATIVE; QUINOLINE DERIVATIVE; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; NONHUMAN; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE;

EID: 0036412954     PISSN: 07930283     EISSN: None     Source Type: Journal    
DOI: 10.1515/HC.2002.8.4.339     Document Type: Article

References (9)

1. th Programme Report of the UNDP/World Bank/WHO, Special Programme for Research and Training in Tropical Disease, Geneva. (1995).
2. J. A. Castro and E. G. Díaz de Torranzo, Biomed. Envir. Sci., 1, 19 (1988).
3. R. A. Tapia, Y. Prieto, G. Zamora, A. Morello and Y. Repetto, Heterocycl. Commun., 6, 539 (2000).
4. R. Cassis, R. Tapia and J. A. Valderrama, Synth. Commun., 15, 125 (1985).
5. L. A. Paquette and W. C. Farley, J. Org. Chem., 32, 2725 (1967).
6. L. Skrzypek, Heterocycles, 48, 71 (1998).
7. D. De, L. D. Byers and D. J. Krogstad, J. Heterocycl. Chem., 34, 315 (1997)
8. A. R. Surrey and H. F. Hammer, J. Am. Chem. Soc., 68, 113 (1946).
9. A. Rojas de Arias, A. Inchausti, A. Ascurra, N. Fleitas, E. Rodriguez and A. Fournet, Phytother. Res., 8, 141 (1994).