BAY 43-9006: Early clinical data in patients with advanced solid malignancies

Current Pharmaceutical Design

Volumn 8, Issue 25, 2002, Pages 2249-2253

  Hotte, Sebastien J ^a   Hirte, Hal W ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

BAY 43 9006; Efficacy; Pharmacokinetics; Phase I study; Raf kinase; Review; Solid tumours; Toxicity

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; RAF PROTEIN; RAS PROTEIN; SORAFENIB; UNCLASSIFIED DRUG;

ABDOMINAL CRAMP; AREA UNDER THE CURVE; ARTICLE; CELL GROWTH; CHEILITIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG HALF LIFE; DRUG TOLERABILITY; FOOD DRUG INTERACTION; GASTROINTESTINAL TOXICITY; HUMAN; MAJOR CLINICAL STUDY; NAUSEA; PHASE 1 CLINICAL TRIAL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; PRURITUS; RASH; SIGNAL TRANSDUCTION; SKIN TOXICITY; SOLID TUMOR;

ANIMALS; ANTINEOPLASTIC AGENTS; BENZENESULFONATES; CLINICAL TRIALS, PHASE I; HUMANS; NEOPLASMS; PYRIDINES;

EID: 0036402628     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/1381612023393053     Document Type: Article

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