Polymorphism in codons 10 and 25 of the transforming growth factor-beta 1 (TGF-β1) gene in patients with invasive squamous cell carcinoma of the uterine cervix

European Journal of Immunogenetics

Volumn 29, Issue 5, 2002, Pages 417-421

  Stanczuk, G A ^a,b   Tswana, S A ^a   Bergstrom, S ^b   Sibanda, E N ^a,c  

^a UNIVERSITY OF ZIMBABWE   (Zimbabwe)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIV OF ZIMBABWE MEDICAL SCHOOL   (Zimbabwe)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; ALLELE; ARTICLE; CARCINOGENESIS; CODON; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; HUMAN; INVASIVE CARCINOMA; MAJOR CLINICAL STUDY; ONCOGENE; POINT MUTATION; PRIORITY JOURNAL; UTERINE CERVIX CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; FEMALE; HUMANS; MIDDLE AGED; NEOPLASM INVASIVENESS; POLYMORPHISM, GENETIC; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UTERINE CERVICAL NEOPLASMS;

PAPILLOMAVIRUS;

EID: 0036400308     PISSN: 09607420     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2370.2002.00347.x     Document Type: Article

References (27)

1. Awad, M.R., El-Gamel, A., Hasleton, P., Turner, D.M., Sinnott, P. & Hutchinson, I.V. (1998) Genotypic variation in the transforming growth factor-β1 gene. Transplantation, 66, 1014.
2. Bascom, C.C., Wolfshohl, R.J., Coffey, R.J., Madisen, L., Webb, N.R., Purchio, A.R., Derynck, R. & Moses, H.L. (1989) Complex regulation of transforming growth factor β1, β2, and β3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factor β1 and β2. Molecular Cell Biology, 9, 5508.
3. Braun, L., Durst, M., Nikumo, R., Crowley, A. & Robinson, M. (1992) Regulation of growth and gene expression in human papillomavirus-transformed keratinocytes by transforming growth factor-beta: implications for the control of papillomavirus infection. Molecular Carcinogenesis, 6, 100.
4. Coffey, R.J., Bascom, C.C., Sipes, N.J., Graves-Deal, R., Weissman, B.E. & Moses, H.L. (1988) Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor-β. Molecular Cell Biology, 8, 3088.
5. Comerci, J.T., Runowicz, C.D., Flanders, K.C., De Victoria, C., Fields, A.L., Kadish, A.S. & Goldberg, G.L. (1996) Altered expression of transforming growth factor-beta 1 in cervical neoplasia as an early biomarker in carcinogenesis of the uterine cervix. Cancer, 77, 1107.
6. Dagnino, L., Pietenpol, J.A., Yang, E.Y. & Moses, H.L. (1993) Transforming growth factor regulation of keratinocyte growth. Recent Results in Cancer Research, 128, 15.
7. Dickson, J., Davidson, S.E., Hunter, R.D. & West, C.M. (2000) Pretreatment plasma TGF-beta 1 levels are prognostic for survival but not morbidity following radiation therapy of carcinoma of the cervix. International Journal of Radiation Oncology, Biology and Physics, 48, 991.
8. El-Gamel, A., Awad, M.R., Hasleton, P., Yonan, N.A., Hutchinson, J.A., Campbell, C.S., Rahman, A.H., Deiraniya, A.K., Sinnett, P.J. & Hutchinson, I.V. (1999) Transforming growth factor-beta (TGF-β1) genotype and lung allograft fibrosis. Journal of Heart and Lung Transplantation, 18, 517.
9. El-Sherif, A.M., Seth, R., Tighe, P.J. & Jenkins, D. (2000) Decreased synthesis and expression of TGF-beta1, beta2, and beta3 in epithelium of HPV 16-positive cervical precancer: a study by microdissection, quantitative RT-PCR, and immunocytochemistry. Journal of Pathology, 192, 494.
10. Farley, J., Gray, K., Nycum, L., Prentice, M., Birrer, M.J. & Jakowlew, S.B. (2000) Endocervical cancer is associated with an increase in the ligands and receptors for transforming growth factor-beta and contrasting decrease in p27 (Kip1). Gynecological Oncology, 78, 113.
11. Giannini, S.L., Al-Saleh, W., Piron, H., Jacobs, N., Doyen, J., Boniver, J. & Delvenne, P. (1998) Cytokine expression in squamous intraepithelial lesions of the uterine cervix: implications for the generation of local immunosuppression. Clinical and Experimental Immunology, 113, 183.
12. Glick, A.B., Kulkarni, A.B., Tennenbaum, T., Henning, H., Flanders, K.C., O'Rielly, M., Sporn, M.B., Karlsson, S. & Yuspa, S.H. (1993) Loss of expression of transforming growth factor β in skin and skin tumors is associated with hyperproliferation and high risk for malignant conversion. Proceedings of the National Academy of Sciences of the USA, 90, 6076.
13. Grainger, D.J., Heathcote, K., Chiano, M., Snledor, H., Kemp, P.R., Metcalfe, J.C., Carter, N.D. & Spector, T.D. (1999) Genetic control of the circulating concentration of transforming growth factor type beta-1. Human Molecular Genetics, 8, 93.
14. Harima, Y., Sawada, S., Nagata, K., Sougawa, M. & Ohnishi, T. (2001) Chromosome 6p21.2, 18q21.2 and human papilloma virus (HPV) DNA can predict prognosis of cervical cancer after radiotherapy. International Journal of Cancer, 95, 286.
15. Hutchinson, I.V., Turner, D.M., Sankaran, D., Awad, M.R. & Sinnott, P.J. (1998) Influence of cytokine genotypes on allograft rejection. Transplantation Proceedings, 30, 862.
16. Kang, S.H., Won, K., Chung, H.W., Jong, H.S., Song, Y.S., Kim, S.J., Bang, Y.J. & Kim, N.K. (1998) Genetic integrity of transforming factor beta (TGF-beta) receptors in cervical carcinoma cell lines: loss of growth sensitivity but conserved transcriptional response to TGF-beta. International Journal of Cancer, 77, 620.
17. Kersemaekers, A.-M.F., van de Vijver, M., Kenter, G.G. & Fleuren, G.J. (1999) Genetic alterations during the progression of squamous cell carcinomas of the uterine cervix. Genes, Chromosomes and Cancer, 26, 346.
18. Kim, J.W., Kim, H.S., Kim, I.K., Kim, M.R., Cho, E.Y., Kim, H.K., Lee, J.M. & Namkoong, S.E. (1998) Transforming growth factor-beta 1 induces apoptosis through down-regulation of c-muc gene and over expression of p27Kip1 protein in cervical carcinoma. Gynaecological Oncology, 69, 230.
19. Markowitz, S.D. & Roberts, A.B. (1996) Tumor suppressor activity of the TGF-beta pathway in human cancers. Cytokine and Growth Factor Reviews, 7, 93.
20. Moses, H.L., Yang, E.Y. & Pietenpol, J.A. (1990) TGF-β stimulation and inhibition of cell proliferation: new mechanistic insights. Cell, 63, 245.
21. Ozbun, M.A. & Meyers, C. (1996) Transforming growth factor beta 1 induces differentiation in human papillomavirus-positive keratinocytes. Journal of Virology, 70, 5437.
22. Perrey, C., Pravica, V., Sinnott, P.J. & Hutchinson, I.V. (1998) Genotyping for polymorphisms in interferon-γ, interleucin-10, transforming growth factor-β1 and tumour necrosis factor-α genes: a technical report. Transplant Immunology, 6, 193.
23. Perrey, C., Turner, S.J., Pravica, V., Howell, W.M. & Hutchinson, I.V. (1999) ARMS-PCR methodologies to determine IL-10, TNF-alpha, TNF-beta and TGF-beta 1 gene polymorphisms. Transplant Immunology, 7, 127.
24. Shipely, G.D., Pittelkow, M.R., Wille, J.J., Scott, R.E. & Moses, H.L. (1986) Reversible inhibition of normal human prokeratinocyte proliferation by the type β transforming growth factor inhibition in serum free medium. Cancer Research, 46, 2068.
25. Stanczuk, G.A., Sibanda, E.N., Perrey, C., Chirara, M., Pravica, V., Hutchinson, I.V. & Tswana, S.A. (2001) Cancer of the uterine cervix may be significantly associated with gene polymorphism coding for increased IL-10 production. International Journal of Cancer, 94, 792.
26. Suthanthiran, M., Li, B., Song, J.O., Ding, R., Sharma, V.K., Schwartz, J.E. & August, P. (2000) Transforming growth factor-β1 hyper-expression in African-American hypertensives: a novel mediator of hypertension and/or target organ damage. Proceedings of the National Academy of Sciences of the USA, 97, 3479.
27. Xu, X.C., Mitchell, M.F., Silva, E., Jetten, A. & Lotan, R. (1999) Decreased expression of retinoic acid receptors, transforming growth factor beta, involucrin, and cornifin in cervical intraepithelial neoplasia. Clinical Cancer Research, 5, 1503.