메뉴 건너뛰기




Volumn 19, Issue 2, 2002, Pages 127-131

Immunobiology and pathophysiology of heparin-induced thrombocytopenia/thrombosis syndrome - An update

Author keywords

Antiheparin PF IV antibodies; Antithrombin drugs; Autoimmune disorder; Heparin induced thrombocytopenia (HIT); Pathophysiology of HIT; Platelet activation

Indexed keywords

ANTICOAGULANT AGENT; BIOLOGICAL MARKER; CD32 ANTIGEN; CELL ADHESION MOLECULE; CHEMOKINE; GLYCOSAMINOGLYCAN; HEPARIN; IMMUNOGLOBULIN G ANTIBODY; LOW MOLECULAR WEIGHT HEPARIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; REVIPARIN; THROMBOCYTE ANTIBODY; THROMBOCYTE FACTOR 4; THROMBOPLASTIN;

EID: 0036399248     PISSN: 13007777     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (5)

References (28)
  • 1
    • 0029440183 scopus 로고
    • Heparin-induced thrombocytopenia
    • Fahey VA. Heparin-induced thrombocytopenia. J Vasc Nurs 1995;13:112.
    • (1995) J Vasc Nurs , vol.13 , pp. 112
    • Fahey, V.A.1
  • 2
    • 0026844620 scopus 로고
    • Heparin-induced thrombocytopenia
    • Chong BH. Heparin-induced thrombocytopenia. Aust N Z J Med 1992;22:145.
    • (1992) Aust N Z J Med , vol.22 , pp. 145
    • Chong, B.H.1
  • 3
    • 0035125405 scopus 로고    scopus 로고
    • Heparin and low-molecular-weight heparin: Mechanisms of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety
    • Hirsh J, Warkentin TE, Shaughnessy SG, et al. Heparin and low-molecular-weight heparin: Mechanisms of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety. Chest 2001;119:64A.
    • (2001) Chest , vol.119
    • Hirsh, J.1    Warkentin, T.E.2    Shaughnessy, S.G.3
  • 4
    • 0030281338 scopus 로고    scopus 로고
    • A 14 year study of heparin-induced thrombocytopenia
    • Warkentin TE, Kelton JG. A 14 year study of heparin-induced thrombocytopenia. Am J Med 1996;101:502.
    • (1996) Am J Med , vol.101 , pp. 502
    • Warkentin, T.E.1    Kelton, J.G.2
  • 6
    • 0011016348 scopus 로고    scopus 로고
    • Assessment of arterial and venous thrombosis
    • In: Loscalzo J, Schafer A, (eds); Balitimore: Williams & Wilkins
    • Creager MA, Beckman JA. Assessment of arterial and venous thrombosis. In: Loscalzo J, Schafer A, (eds). Thrombosis and Hemorrhage. Balitimore: Williams & Wilkins, 1998:491.
    • (1998) Thrombosis and Hemorrhage , pp. 491
    • Creager, M.A.1    Beckman, J.A.2
  • 7
    • 0029097106 scopus 로고
    • Critical role of pulmonary angiography in the diagnosis of pulmonary emboli following cardiac surgery
    • Ramos RS, Salem BL, Haikal, et al. Critical role of pulmonary angiography in the diagnosis of pulmonary emboli following cardiac surgery. Cath Cardiovasc Dis 1995;36:112.
    • (1995) Cath Cardiovasc Dis , vol.36 , pp. 112
    • Ramos, R.S.1    Salem, B.L.2    Haikal3
  • 8
    • 0029878458 scopus 로고    scopus 로고
    • Pathogenicity of IgA and/or IgM antibodies to UFH-PF IV complexes with UFH-induced thrombocytopenia
    • Amiral J, Wolf M, Fischer A, et al. Pathogenicity of IgA and/or IgM antibodies to UFH-PF IV complexes with UFH-induced thrombocytopenia. Br J Haematol 1996;92:954.
    • (1996) Br J Haematol , vol.92 , pp. 954
    • Amiral, J.1    Wolf, M.2    Fischer, A.3
  • 9
    • 0032944681 scopus 로고    scopus 로고
    • Selectins in the HIT syndrome: Pathophysiologic role and therapeutic modulation
    • Fareed J, Walenga JM, Hoppensteadt DA, et al. Selectins in the HIT syndrome: Pathophysiologic role and therapeutic modulation. Semin Thromb Hemost 1999;25(Suppl 1):37.
    • (1999) Semin Thromb Hemost , vol.25 , Issue.SUPPL. 1 , pp. 37
    • Fareed, J.1    Walenga, J.M.2    Hoppensteadt, D.A.3
  • 10
    • 0033730964 scopus 로고    scopus 로고
    • Pathophysiology of heparin-induced thrombocytopenia: Clinical and diagnostic implications - A review
    • Fabris F, Ahmad S, Cella G, et al. Pathophysiology of heparin-induced thrombocytopenia: Clinical and diagnostic implications - a review. Arch Pathol Lab Med 2000;124:1657.
    • (2000) Arch Pathol Lab Med , vol.124 , pp. 1657
    • Fabris, F.1    Ahmad, S.2    Cella, G.3
  • 12
    • 0026638091 scopus 로고
    • Platelet factor IV complexed to heparin is the target for antibodies generated in heparin induced thrombocytopenia
    • Amiral J, Bridey F, Dreyfus M, et al. Platelet factor IV complexed to heparin is the target for antibodies generated in heparin induced thrombocytopenia. Thromb Haemost 1992;68:95.
    • (1992) Thromb Haemost , vol.68 , pp. 95
    • Amiral, J.1    Bridey, F.2    Dreyfus, M.3
  • 13
    • 0031981850 scopus 로고    scopus 로고
    • The biological basis of immune heparin-induced thrombocytopenia
    • Amiral J, Marfaing-Koka A, Poncz M, et al. The biological basis of immune heparin-induced thrombocytopenia. Platelets 1998;9:77.
    • (1998) Platelets , vol.9 , pp. 77
    • Amiral, J.1    Marfaing-Koka, A.2    Poncz, M.3
  • 14
    • 0027065097 scopus 로고
    • Structure and function of platelet-derived cytokines of the β-thromboglobulin/interleukin 8 family
    • Brandt E, Flad HD. Structure and function of platelet-derived cytokines of the β-thromboglobulin/interleukin 8 family. Platelets 1992;3:295.
    • (1992) Platelets , vol.3 , pp. 295
    • Brandt, E.1    Flad, H.D.2
  • 16
    • 0019192750 scopus 로고
    • The multiple complexes formed by the interaction of platelet factor IV with heparin
    • Bock PE, Luscombe M, Marshall SE, et al. The multiple complexes formed by the interaction of platelet factor IV with heparin. Biochem J 1980;191:769.
    • (1980) Biochem J , vol.191 , pp. 769
    • Bock, P.E.1    Luscombe, M.2    Marshall, S.E.3
  • 17
    • 0032747473 scopus 로고    scopus 로고
    • Functional heterogeneity of antiheparin-platelet factor IV antibodies: Implications in the pathogenesis of HIT syndrome
    • Ahmad S, Walenga JM, Jeske WP, et al. Functional heterogeneity of antiheparin-platelet factor IV antibodies: Implications in the pathogenesis of HIT syndrome. Clin Appl Thromb Hemost 1999;5(Suppl 1):32A.
    • (1999) Clin Appl Thromb Hemost , vol.5 , Issue.SUPPL. 1
    • Ahmad, S.1    Walenga, J.M.2    Jeske, W.P.3
  • 18
    • 4243986357 scopus 로고    scopus 로고
    • Lack of thrombocytopenic response after low molecular weight heparins usage is due to the generation of non-functional antiheparin-platelet factor IV antibodies
    • Ahmad S, Walenga JM, Jeske WP, et al. Lack of thrombocytopenic response after low molecular weight heparins usage is due to the generation of non-functional antiheparin-platelet factor IV antibodies. J Am Coll Cardiol 2000;35(Suppl A):316A.
    • (2000) J Am Coll Cardiol , vol.35 , Issue.SUPPL. A
    • Ahmad, S.1    Walenga, J.M.2    Jeske, W.P.3
  • 19
    • 0031871804 scopus 로고    scopus 로고
    • Effect of SR121566A, a potent GPIIb/IIIa antagonist on the HIT serum-induced platelet mediated activation of human endothelial cells
    • Herbert J-M, Savi P, Jeske WP, et al. Effect of SR121566A, a potent GPIIb/IIIa antagonist on the HIT serum-induced platelet mediated activation of human endothelial cells. Thromb Haemost 1998;80:326.
    • (1998) Thromb Haemost , vol.80 , pp. 326
    • Herbert, J.-M.1    Savi, P.2    Jeske, W.P.3
  • 20
    • 0036162984 scopus 로고    scopus 로고
    • Antiplatelet factor IV/heparin antibodies from patients with heparin-induced thrombocytopenia provoke direct activation of microvascular endothelial cells
    • Blank M, Shoenfeld Y, Tavor S, et al. Antiplatelet factor IV/heparin antibodies from patients with heparin-induced thrombocytopenia provoke direct activation of microvascular endothelial cells. Int Immunol 2002;14:121.
    • (2002) Int Immunol , vol.14 , pp. 121
    • Blank, M.1    Shoenfeld, Y.2    Tavor, S.3
  • 21
    • 0034235401 scopus 로고    scopus 로고
    • Morphological analysis of microparticle generation in heparin-induced thrombocytopenia
    • Hughes M, Hayward CPM, Warkentin TE, et al. Morphological analysis of microparticle generation in heparin-induced thrombocytopenia. Blood 2000;96:188.
    • (2000) Blood , vol.96 , pp. 188
    • Hughes, M.1    Hayward, C.P.M.2    Warkentin, T.E.3
  • 22
    • 0002056227 scopus 로고    scopus 로고
    • Management of heparin-induced thrombocytopenia and heparin-induced thrombocytopenia with thrombosis syndrome
    • Walenga JM, Lewis BE, Hoppensteadt DA, et al. Management of heparin-induced thrombocytopenia and heparin-induced thrombocytopenia with thrombosis syndrome. Clin Appl Thromb Hemost 1997;3(Suppl 1):53A.
    • (1997) Clin Appl Thromb Hemost , vol.3 , Issue.SUPPL. 1
    • Walenga, J.M.1    Lewis, B.E.2    Hoppensteadt, D.A.3
  • 23
    • 0035283104 scopus 로고    scopus 로고
    • Effects of a low-molecular-weight heparin on thrombus regression and recurrent thromboembolism in patients with deep-vein thrombosis
    • Breddin HK, Hach-Wunderle V, Nakov, et al. Effects of a low-molecular-weight heparin on thrombus regression and recurrent thromboembolism in patients with deep-vein thrombosis. N Engl J Med 2001;344:626.
    • (2001) N Engl J Med , vol.344 , pp. 626
    • Breddin, H.K.1    Hach-Wunderle, V.2    Nakov3
  • 24
    • 0036825957 scopus 로고    scopus 로고
    • Differential effects of clivarin and heparin in patients undergoing hip and knee surgery for the generation of anti-heparin-platelet factor IV antibodies
    • in press
    • Ahmad S, Haas S, Hoppensteadt DA, et al. Differential effects of clivarin and heparin in patients undergoing hip and knee surgery for the generation of anti-heparin-platelet factor IV antibodies. Thromb Res 2002; in press.
    • (2002) Thromb Res
    • Ahmad, S.1    Haas, S.2    Hoppensteadt, D.A.3
  • 25
    • 4243967142 scopus 로고    scopus 로고
    • Upregulation of tissue factor pathway inhibitor by a low-molecular-weight heparin, clivarin, is associated with decreased prevalence of antiheparin-PF IV antibodies: Diagnostic and therapeutic implications
    • Ahmad S, Lietz H, Daud AN, et al. Upregulation of tissue factor pathway inhibitor by a low-molecular-weight heparin, clivarin, is associated with decreased prevalence of antiheparin-PF IV antibodies: Diagnostic and therapeutic implications. Int Angiol 2001;20(Suppl 1):42A.
    • (2001) Int Angiol , vol.20 , Issue.SUPPL. 1
    • Ahmad, S.1    Lietz, H.2    Daud, A.N.3
  • 26
    • 0037087162 scopus 로고    scopus 로고
    • Prevalence, isotype, and functionality of anti-heparin-platelet factor IV antibodies in patients treated with heparin and clinically suspected for heparin-induced thrombocytopenia: The pathogenic role of IgG
    • Untch B, Ahmad S, Jeske WP, et al. Prevalence, isotype, and functionality of anti-heparin-platelet factor IV antibodies in patients treated with heparin and clinically suspected for heparin-induced thrombocytopenia: The pathogenic role of IgG. Thromb Res 2002;105:17.
    • (2002) Thromb Res , vol.105 , pp. 17
    • Untch, B.1    Ahmad, S.2    Jeske, W.P.3
  • 27
    • 0034937429 scopus 로고    scopus 로고
    • Determination of heparin-platelet factor IV-IgG antibodies improves diagnosis of heparin-induced thrombocytopenia
    • Lindhoff-Last E, Gerdsen F, Achermann H, et al. Determination of heparin-platelet factor IV-IgG antibodies improves diagnosis of heparin-induced thrombocytopenia. Br J Haematol 2001;113:886.
    • (2001) Br J Haematol , vol.113 , pp. 886
    • Lindhoff-Last, E.1    Gerdsen, F.2    Achermann, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.