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Volumn 297, Issue 2, 2002, Pages 202-205
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Stereoselective hydroxylation of 4-methyl-2-cyclohexenone in rats: Its relevance to R-(+)-pulegone-mediated hepatotoxicity
a
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Author keywords
4 Methyl 2 cyclohexenone; CD spectrum; Cytochrome P 450 system; Hepatotoxicity; Optical rotation; p Cresol; R (+) Pulegone; Stereoselective hydroxylation
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Indexed keywords
4 METHYL 2 CYCLOHEXENONE;
CYTOCHROME P450;
KETONE DERIVATIVE;
OXYGEN;
PARA CRESOL;
PULEGONE;
REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ANIMAL TISSUE;
ARTICLE;
CIRCULAR DICHROISM;
CONTROLLED STUDY;
ENANTIOMER;
ENZYME SUBSTRATE;
HYDROXYLATION;
ISOLATION PROCEDURE;
LIVER MICROSOME;
LIVER TOXICITY;
MALE;
NONHUMAN;
OPTICAL ROTATION;
PRIORITY JOURNAL;
PURIFICATION;
RAT;
SPECTRUM;
STEREOCHEMISTRY;
ANIMALS;
CIRCULAR DICHROISM;
CRESOLS;
CYCLOHEXANONES;
CYTOCHROME P-450 ENZYME SYSTEM;
HYDROXYLATION;
LIVER;
MICROSOMES, LIVER;
MOLECULAR CONFORMATION;
MOLECULAR STRUCTURE;
MONOTERPENES;
NADP;
OXYGEN;
RATS;
STEREOISOMERISM;
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EID: 0036398961
PISSN: 0006291X
EISSN: None
Source Type: Journal
DOI: 10.1016/S0006-291X(02)02179-4 Document Type: Article |
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Times cited : (9)
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References (21)
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