Role of C-5 chiral center in R-(+)-pulegone-mediated hepatotoxicity: Metabolic disposition and toxicity of 5,5-dimethyl-2-(1-methylethylidene)- cyclohexanone in rats

Drug Metabolism and Disposition

Volumn 28, Issue 7, 2000, Pages 833-844

  Thulasiram, Hirekodathakallu V ^a   Gadad, Andanappa K ^a   Madyastha, Madhava K ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLCHOLANTHRENE; ALANINE AMINOTRANSFERASE; BENZOFURAN DERIVATIVE; CARBON MONOXIDE; CARBON TETRACHLORIDE; CYCLOHEXANONE DERIVATIVE; CYTOCHROME C OXIDASE; CYTOCHROME P450; DRUG METABOLITE; FURANONE DERIVATIVE; GLUCOSE 6 PHOSPHATASE; METYRAPONE; PHENOBARBITAL; PROADIFEN; PULEGONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TERPENE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHIRALITY; CONTROLLED STUDY; DRUG DISPOSITION; DRUG URINE LEVEL; ENZYME BLOOD LEVEL; GAS CHROMATOGRAPHY; LIVER MICROSOME; LIVER PROTECTION; LIVER TOXICITY; MALE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT;

AMINOPYRINE N-DEMETHYLASE; ANIMALS; BIOTRANSFORMATION; CARBON TETRACHLORIDE; CYCLOHEXANONES; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; GLUCOSE-6-PHOSPHATASE; LIVER; MALE; MENTHOL; MICROSOMES, LIVER; MONOTERPENES; RATS; RATS, WISTAR; STEREOISOMERISM;

ANIMALIA;

EID: 0033941437     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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