Thalassemia intermedia: Heterozygous β-thalassemia and co-inheritance of an α gene triplication

Hemoglobin

Volumn 26, Issue 3, 2002, Pages 321-323

  Agarwal, Sarita ^a   Sarwai, Swati ^a   Agarwal, Savita ^a   Gupta, Usha R ^a   Phadke, Shubha ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLOBIN; GLOBIN;

ADULT; ARTICLE; AUTOSOMAL INHERITANCE; BETA THALASSEMIA; BLOOD SAMPLING; BLOOD TRANSFUSION; CLINICAL ARTICLE; ERYTHROCYTE MEMBRANE; FEMALE; GENE DUPLICATION; GENETIC COUNSELING; HETEROZYGOSITY; HUMAN; MALE; PATHOPHYSIOLOGY; POINT MUTATION; POLYMERASE CHAIN REACTION; FRAMESHIFT MUTATION; GENETICS; GENOTYPE; HETEROZYGOTE; INDIA; PHENOTYPE;

ADULT; BETA-THALASSEMIA; FEMALE; FRAMESHIFT MUTATION; GENE DUPLICATION; GENOTYPE; GLOBINS; HETEROZYGOTE; HUMANS; INDIA; MALE; PHENOTYPE; POINT MUTATION;

EID: 0036398935     PISSN: 03630269     EISSN: None     Source Type: Journal    
DOI: 10.1081/HEM-120015038     Document Type: Article

References (4)

1. Camaschella, C.; Kattamis, A.C.; Petroni, D.; Roetto, A.; Sivera, P.; Sbaiz, L.; Cohen, A.; Ohene-Frempong, K.; Trifillis, P.; Surrey, S.; Fortina, P. Different Hematological Phenotypes Caused by the Interaction of Triplicated α Globin Genes and Heterozygous β-Thalassemia. Am. J. Hematol. 1997, 55, 83-88.
2. Colah, R.B.; Nandkarni, A.H.; Mukherjee, M.B.; Gorakshakar, A.C.; Surve, R.; Mohanty, D. β-Thalassaemia Heterozygotes with α-Globin Gene Triplication. Br. J. Haematol 1997, 97, 504-510.
3. Garewal, G.; Fearon, C.W.; Warren, T.C.; Marwaha, N.; Marwaha, R.K.; Mahadik, C.; Kazazian, H.H., Jr. The Molecular Basis of β Thalassaemia in Panjabi and Maharashtrian Indians Includes a Multilocus Etiology Involving Triplicated α Globin Loci. Br. J. Haematol. 1994, 86 (2), 372-376.
4. Agarwal, S.; Pradhan, M.; Gupta, U.R.; Sarwai, S.; Agarwal, S.S. Geographic and Ethnic Distribution of β-Thal Mutations in Uttar Pradesh, India. Hemoglobin 2000, 24 (2), 89-98.