Prosaposin: Threshold rescue and analysis of the "neuritogenic" region in transgenic mice

Molecular Genetics and Metabolism

Volumn 76, Issue 4, 2002, Pages 271-286

  Sun, Ying ^a   Qi, Xiaoyang ^a   Witte, David P ^a   Ponce, Elvira ^a   Kondoh, Keiji ^b   Quinn, Brian ^a   Grabowski, Gregory A ^a  

^a CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^b EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Central nervous system; Glycosphingolipids; Lysosomal hydrolases; Neurotrophic factors; Saposins

Indexed keywords

BETA GLUCOSIDASE; CHIMERIC PROTEIN; COMPLEMENTARY DNA; GLYCOSPHINGOLIPID; ISOPROTEIN; PHOSPHOGLYCERATE KINASE; PROSAPOSIN; SAPOSIN B; SAPOSIN C; SPHINGOLIPID ACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

AGE; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CELL LOSS; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVATION; GENE EXPRESSION; GENE MUTATION; GENETIC CODE; IN VIVO STUDY; KNOCKOUT MOUSE; LIFESPAN; LIPID STORAGE; MOLECULAR BIOLOGY; MOUSE; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PURKINJE CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENE; TRANSGENIC MOUSE; VISCERA; WILD TYPE;

ANIMALS; BRAIN; DNA, COMPLEMENTARY; GLYCOPROTEINS; GLYCOSPHINGOLIPIDS; IN SITU HYBRIDIZATION; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MYELIN BASIC PROTEINS; PERIPHERAL NERVES; PROTEIN PRECURSORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SAPOSINS; SPINAL CORD;

MUS MUSCULUS;

EID: 0036392385     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1096-7192(02)00114-2     Document Type: Article

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