The curly-tail (ct) mouse, an animal model of neural tube defects, displays altered homocysteine metabolism without folate responsiveness or a defect in Mthfr

Molecular Genetics and Metabolism

Volumn 76, Issue 4, 2002, Pages 297-304

  Tran, Pamela ^a   Hiou Tim, Francois ^a   Frosst, Phyllis ^a   Lussier Cacan, Suzanne ^b   Bagley, Pamela ^c   Selhub, Jacob ^c   Bottiglieri, Teodoro ^d   Rozen, Rima ^a  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^c TUFTS UNIVERSITY   (United States)

^d BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Choline; Ct Mouse; Diets; Folate; Homocysteine; Mthfr; NTD

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CHOLINE; FOLIC ACID; HOMOCYSTEINE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; ENZYME ACTIVITY; FOLATE METABOLISM; GENE LOCUS; GENE MAPPING; GENE SEQUENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INBORN ERROR OF METABOLISM; INCIDENCE; LIVER LEVEL; MALE; MOUSE; MOUSE STRAIN; NEURAL TUBE DEFECT; NONHUMAN; NUTRITIONAL DEFICIENCY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEFECT; REGULATORY MECHANISM;

5' FLANKING REGION; ANIMALS; CHOLATES; DISEASE MODELS, ANIMAL; FOLIC ACID; HOMOCYSTEINE; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MICE; MICE, INBRED C57BL; NEURAL TUBE DEFECTS; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS;

ANIMALIA;

EID: 0036389766     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1096-7192(02)00108-7     Document Type: Article

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