Targeting of MPEG-protected polyamino acid carrier to human E-selectinin vitro

Amino Acids

Volumn 23, Issue 1-3, 2002, Pages 301-308

  Kang, H W ^a   Weissleder, R ^a   Bogdanov Jr , A ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Antibody; E selectin; Endothelium; Graft copolymer; IL 1 ; Indocyanine; Optical imaging

Indexed keywords

AMINO ACID COPOLYMER; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INDOCYANINE GREEN; INTERLEUKIN 1BETA; MACROGOL; MONOCLONAL ANTIBODY; POLYAMINOACID; POLYLYSINE; THIOL GROUP;

BINDING AFFINITY; CELL ACTIVATION; CELL POPULATION; CONFERENCE PAPER; CONJUGATION; CONTROLLED STUDY; COVALENT BOND; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMAGING; IN VITRO STUDY; PRIORITY JOURNAL;

AMINO ACIDS; CARBOCYANINES; CELLS, CULTURED; DRUG CARRIERS; E-SELECTIN; ENDOTHELIUM, VASCULAR; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; INTERLEUKIN-1; MICROSCOPY, FLUORESCENCE; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; POLYETHYLENE GLYCOLS;

EID: 0036389418     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-001-0142-2     Document Type: Conference Paper

References (24)

1. Anderson SA, Rader RK, Westlin WF, Null C, Jackson D, Lanza GM, Wickline SA, Kotyk JJ (2000) Magnetic resonance contrast enhancement of neovasculature with alpha(v)beta(3)-targeted nanoparticles. Magn Reson Med 44: 433-439
2. Bevilacqua MP, Pober JS, Mendrick DL, Cotran RS, Gimbrone MA, Jr. (1987) Identification of an inducible endothelial-leukocyte adhesion molecule. Proc Natl Acad Sci USA 84: 9238-9242
3. Bischoff J, Brasel C, Kraling B, Vranovska K (1997) E-selectin is upregulated in proliferating endothelial cells in vitro. Microcirculation 4: 279-287
4. Bogdanov AA, Jr., Weissleder R, Frank HW, Bogdanova AV, Nossif N, Schaffer BK, Tsai E, Papisov MI, Brady TJ (1993) A new macromolecule as a contrast agent for MR angiography: preparation, properties, and animal studies. Radiology 187: 701-706
5. Bogdanov AA, Martin C, Bogdanova AV, Brady TJ, Weissleder R (1996) An adduct of cis-diamminedichloroplatinum(II) and poly(ethylene glycol)poly(L-lysine)-succinate: synthesis and cytotoxic properties. Bioconj Chem 7: 144-149
6. Brasch R, Pham C, Shames D, Roberts T, van Dijke K, van Bruggen N, Mann J, Ostrowitzki S, Melnyk O (1997) Assessing tumor angiogenesis using macromolecular MR imaging contrast media. J Magn Reson Imaging 7: 68-74
7. Bredow S, Lewin M, Hofmann B, Marecos E, Weissleder R (2000) Imaging of tumour neovasculature by targeting the TGF-b binding receptor endoglin. Eur J Cancer 36: 675-681
8. Callahan RJ, Bogdanov A, Jr., Fischman AJ, Brady TJ, Weissleder R (1998) Preclinical evaluation and phase I clinical trial of a 99mTc-labeled synthetic polymer used in blood pool imaging. Am J Roentgenol 171: 137-143
9. Duncan RJC, Weston P, Wrigglesworth R (1983) A new reagent which may be used to introduce sulfhydryl group into proteins, and its use in the preparation of counjugate for immunoasay. Analyt Biochem 132: 68-73
10. Gamble J, Meyer G, Noack L, Furze J, Matthias L, Kovach N, Harlant J, Vadas M (1999) B1 integrin activation inhibits in vitro tube formation: effects on cell migration, vacuole coalescence and lumen formation. Endothelium 7: 23-34
11. Gimbrone MA, Jr., Topper JN, Nagel T, Anderson KR, Garcia-Cardena G (2000) Endothelial dysfunction, hemodynamic forces, and atherogenesis. Ann NY Acad Sci 902: 230-239
12. Haubner R, Wester HJ, Weber WA, Mang C, Ziegler SI, Goodman SL, Senekowitsch-Schmidtke R, Kessler H, Schwaiger M (2001) Noninvasive imaging of alpha(v)beta3 integrin expression using 18F-labeled RGD-containing glycopeptide and positron emission tomography. Cancer Res 61: 1781-1785
13. Kiely JM, Cybulsky MI, Luscinskas FW, Gimbrone MA, Jr. (1995) Immunoselective targeting of an anti-thrombin agent to the surface of cytokine-activated vascular endothelial cells. Arteriosclerosis Thrombosis Vasc Biol 15: 1211-1218
14. Kraling BM, Razon MJ, Boon LM, Zurakowski D, Seachord C, Darveau RP, Mulliken JB, Corless CL, Bischoff J (1996) E-selectin is present in proliferating endothelial cells in human hemangiomas. Am J Pathol 148: 1181-1191
15. Mahmood U, Tung CH, Bogdanov A, Jr., Weissleder R (1999) Near-infrared optical imaging of protease activity for tumor detection. Radiology 213: 866-870
16. Marecos E, Weissleder R, Bogdanov A, Jr. (1998) Antibody-mediated versus nontargeted delivery in a human small cell lung carcinoma model. Bioconj Chem 9: 184-191
17. Mayer B, Spatz H, Funke I, Johnson JP, Schildberg FW (1998) De novo expression of the cell adhesion molecule E-selectin on gastric cancer endothelium. Langenbecks Arch Surg 383: 81-86
18. Neri D, Carnemolla B, Nissim A, Leprini A, Querze G, Balza E, Pini A, Tarli L, Halin C, Neri P, Zardi L, Winter G (1997) Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform. Nature Biotechnol 15: 1271-1275
19. Nguyen M (1997) Angiogenic factors as tumor markers. Invest New Drugs 15: 29-37
20. Sipkins DA, Cheresh DA, Kazemi MR, Nevin LM, Bednarski MD, Li KC (1998) Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging. Nature Med 4: 623-626
21. Spragg DD, Alford DR, Greferath R, Larsen CE, Lee KD, Gurtner GC, Cybulsky MI, Tosi PF, Nicolau C, Gimbrone MA, Jr. (1997) Immunotargeting of liposomes to activated vascular endothelial cells: a strategy for site-selective delivery in the cardiovascular system. Proc Natl Acad Sci USA 94: 8795-8800
22. Weissleder R, Cheng HC, Marecos E, Kwong K, Bogdanov A, Jr. (1998) Non-invasive in vivo mapping of tumour vascular and interstitial volume fractions. Eur J Cancer 34: 1448-1454
23. Weissleder R, Tung CH, Mahmood U, Bogdanov A, Jr. (1999) In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nature Biotechnol 17: 375-378
24. Zinn KR, Chaudhuri TR, Smyth CA, Wu Q, Liu HG, Fleck M, Mountz JD, Mountz JM (1999) Specific targeting of activated endothelium in rat adjuvant arthritis with a 99mTc-radiolabeled E-selectin-binding peptide. Arthritis Rheumatism 42: 641-649