Influence of the relA gene on ribosome frameshifting

Molecular Genetics and Genomics

Volumn 268, Issue 1, 2002, Pages 81-86

  Masucci, J ^a   Gallant, J ^a   Lindsley, D ^a   Atkinson, J ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Amino acid limitation; relA; Ribosomal frameshifting; Stringent response

Indexed keywords

AMINOACYL TRANSFER RNA; ISOLEUCINE TRANSFER RNA; LEUCINE; LYSINE TRANSFER RNA; PROTEIN; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL MUTANT; CODON; CONTROLLED STUDY; GENE LOCUS; GENOTYPE; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; RIBOSOMAL FRAMESHIFTING; WILD TYPE;

ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FRAMESHIFT MUTATION; FRAMESHIFTING, RIBOSOMAL; GENE DELETION; GENES, BACTERIAL; HISTIDINE; KINETICS; LIGASES; RIBOSOMES;

EID: 0036383462     PISSN: 16174615     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00438-002-0725-y     Document Type: Article

References (28)

1. Barak Z, Lindsley D, Gallant J (1996) On the mechanism of leftward frameshifting at several hungry codons. J Mol Biol 256:676-684
2. Björk GR (1992) The role of modified nucleosides in tRNA interactions. In: Hatfield DL, Lee BJ, Pirtle RM (eds) Transfer RNA in protein synthesis. CRC Press, Boca Raton, Fla., pp 23-85
3. Brierley I, Meredith MR, Bloys AJ, Hagervall TG (1997) Expression of a coronavirus ribosomal frameshift signal in Escherichia coli: influence of tRNA anticodon modification on frameshifting. J Mol Biol 270:360-373
4. Curran J (1998) Modified nucleosides in translation. In: Grosjean H, Benne R (eds) Modification and editing of RNA. ASM Press, Washington, D.C.
5. Farabaugh P J (1996) Programmed translational frameshifting. Microbiol Rev 60:103-134
6. Farabaugh PJ (1997) Programmed alternative reading of the genetic code. RG Landes, Austin, Tex.
7. Fiil N, Friesen JD (1968) Isolation of "relaxed" mutants of Escherichia coli. J Bacteriol 95:729-731
8. Fournier MJ, Webb E, Kichingman GR (1976) General and specific effects of amino acid starvation on the formation of undermodified Escherichia coli phenylalanine tRNA. Biochim Biophys Acta 454:97-113
9. Frey B, Janel G, Michelsen U, Kersten H (1989) Mutations in the Escherichia coli fnr and tgt genes: control of molybdate reductase activity and the cytochrome d complex by fnr. J Bacteriol 171:1524-1530
10. Gallant J, Foley D (1980) On the causes and prevention of mistranslation. In: Chambliss G, Craven GR, Davies J, Davis K, Kahan L, Nomura M (eds) Ribosomes: structure, function and genetics. University Park Press, Baltimore, Md., pp 615-638
11. Gallant J, Lindsley D (1993) Ribosome frameshifting at hungry codons: sequence rules, directional specificity and possible relationship to mobile element behaviour. Biochem Soc Trans 21:817-822
12. Gallant J, Lindsley D, Masucci J (2000) The unbearable lightness of peptidyl-tRNA. In: Garrett RA, Douthwaite SR, Liljas A, Matheson AT, Moore PB, Noller HF (eds) The Ribosome: structure, function, antibiotics, and cellular interactions; ASM Press, Washington, D.C.
13. Kitchingman GR, Fournier MJ (1975) Unbalanced growth and the production of unique transfer ribonucleic acids in relaxed-control Escherichia coli. J Bacteriol 124:1382-1394
14. Kitchingman GR, Fournier MJ (1977) Modification-deficient transfer ribonucleic acids from relaxed control Escherichia coli: structures of the major undermodified phenylalanine and leucine transfer RNAs produced during leucine starvation. Biochemistry 16:2213-2220
15. Kolor K, Lindsley D, Gallant J (1993) On the role of the P-site in leftward ribosome frameshifting at a hungry codon. J Mol Biol 230:1-5
16. Kurland CG (1979) Reading frame errors on ribosomes. In: Celis JE, Smith JF (eds) Nonsense mutations and tRNA suppressors. Academic Press, London, pp 97-108
17. Kurland C, Gallant J (1986) The secret life of the ribosome. pp 127-157. In: Kirkwood TBL, Rosenberger RF, Galas DJ (eds) Accuracy in molecular processes. Chapman and Hall, London
18. Lindsley D, Gallant J (1993) On the directional specificity of ribosome frameshifting at a "hungry" codon. Proc Natl Acad Sci USA 90:5469-5473
19. Lowry OH, Rosenbrough HJ, Farr AL, Randall RJ (1951) Protein synthesis measurement with the Folin phenol reagent. J Biol Chem 191:265-275
20. Monod J (1958) An outline of enzyme induction. Recueil des Travaux Chimiques des Pays-Bas 77:569-592
21. Pardee AB (1962) The synthesis of enzymes. In: The Bacteria, vol 3. Academic Press, New York and London, pp 577-630
22. Peter K, Lindsley D, Peng L, Gallant JA (1992) Context rules of rightward overlapping reading. New Biol 4:520-526
23. Reuter K, Chong S, Ullrich F, Kersten H, Garcia GA (1994) Serine 90 is required for enzymatic activity by the tRNA-guanine transglycosylase from Escherichia coli. Biochemistry 33:7041-7046
24. Silhavy TJ, Berman ML, Enquist LW (1984) Experiments with gene fusions. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
25. Sprinzl M, Steegbor C, Hübel F, Steinberg S (1996) Compilation of tRNA sequences and sequences of tRNA genes. Nucleic Acids Res 24:68-72
26. Urbonavicius J, Qian Q, Durand JMB, Hagervall TG, Björk GR (2001) Improvement of reading frame maintenance is a common function for several tRNA modifications. EMBO J 20:48863-4873
27. Weiss R, Gallant J (1983) Mechanism of ribosome frameshifting during translation of the genetic code. Nature 302:389-393
28. Weiss RB, Gallant JA (1986) Frameshift suppression in aminoacyl-tRNA limited cells. Genetics 112:727-739