20-HETE pathway antagonists inhibit rat small mesenteric artery tone

Microvascular Research

Volumn 64, Issue 2, 2002, Pages 349-352

  Looft Wilson, Robin C ^a,d   Falck, John R ^c   Krishna, U Murali ^c   Gisolfi, Carl V ^a,b  

^a 5 660 Bowen Science Building ^*  (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

17 OCTADECYNOIC ACID; 20 HYDROXYICOSATETRAENOIC ACID; 20 HYDROXYICOSATETRAENOIC ACID RECEPTOR ANTAGONIST; CYTOCHROME P450 INHIBITOR; N METHYLSULFONYL 12,12 DIBROMODODEC 11 ENAMIDE; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTERY DIAMETER; ARTERY TONE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; MALE; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0036382926     PISSN: 00262862     EISSN: None     Source Type: Journal    
DOI: 10.1006/mvre.2002.2440     Document Type: Article

References (19)

1. Alonso-Galicia, M., Falck, J. R., Reddy, K. M., and Roman, R. J. (1999). 20-HETE agonists and antagonists in the renal circulation. Am. J. Physiol. 277, F790-796.
2. Bakker, E. N., Kerkhof, C. J., and Sipkema, P. (1999). Signal transduction in spontaneous myogenic tone in isolated arterioles from rat skeletal muscle. Cardiovasc. Res. 41, 229-236.
3. Chlopicki, S., Nilsson, H., and Mulvany, M. J. (1996). The late part of the myogenic response of rat mesenteric small arteries is inhibited by cytochrome P450 inhibitors. J. Vasc. Res. 33(Suppl.), 48.
4. Frisbee, J. C., Falck, J. R., and Lombard, J. H. (2000). Contribution of cytochrome P-450 omega-hydroxylase to altered arteriolar reactivity with high-salt diet and hypertension. Am. J. Physiol. Heart Circ. Physiol. 278, H1517-1526.
5. Frisbee, J. C., Roman, R. J., Falck, J. R., Krishna, U. M., and Lombard, J. H. (2001a). 20-HETE contributes to myogenic activation of skeletal muscle resistance arteries in Brown Norway and Sprague-Dawley rats. Microcirculation 8, 45-55.
6. Frisbee, J. C., Roman, R. J., Krishna, U. M., Falck, J. R., and Lombard, J. H. (2001b). 20-HETE modulates myogenic response of skeletal muscle resistance arteries from hypertensive Dahl-SS rats. Am. J. Physiol. Heart Circ. Physiol. 280, H1066-1074.
7. Gebremedhin, D., Lange, A. R., Lowry, T. F., Taheri, M. R., Birks, E. K., Hudetz, A. G., Narayanan, J., Falck, J. R., Okamoto, H., Roman, R. J., Nithipatikom, K., Campbell, W. B., and Harder, D. R. (2000). Production of 20-HETE and its role in autoregulation of cerebral blood flow. Circ. Res. 87, 60-65.
8. Harder, D. R., Lange, A. R., Gebremedhin, D., Birks, E. K., and Roman, R. J. (1997). Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue. J. Vasc. Res. 34, 237-243.
9. Harder, D. R., Narayanan, J., Birks, E. K., Liard, J. F., Imig, J. D., Lombard, J. H., Lange, A. R., and Roman, R. J. (1996). Identification of a putative microvascular oxygen sensor. Circ. Res. 79, 54-61.
10. Imig, J. D., Zou, A. P., Ortiz de Montellano, P. R., Sui, Z., and Roman, R. J. (1994). Cytochrome P-450 inhibitors alter afferent arteriolar responses to elevations in pressure. Am. J. Physiol. 266, H1879-1885.
11. Kauser, K., Clark, J. E., Masters, B. S., Ortiz de Montellano, P. R., Ma, Y. H., Harder, D. R., and Roman, R. J. (1991). Inhibitors of cytochrome P-450 attenuate the myogenic response of dog renal arcuate arteries. Circ. Res. 68, 1154-1163.
12. Looft-Wilson, R. C., and Gisolfi, C. V. (2000). Rat small mesenteric artery function after hindlimb suspension. J. Appl. Physiol. 88, 1199-1206.
13. Ma, Y. H., Gebremedhin, D., Schwartzman, M. L., Falck, J. R., Clark, J. E., Masters, B. S., Harder, D. R., and Roman, R. J. (1993). 20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries. Circ. Res. 72, 126-136.
14. Roman, R. J. (2002). P-450 metabolites of arachidonic acid in the control of cardiovascular function. Physiol. Rev. 82, 131-185.
15. VanBavel, E., Giezeman, M. J., Mooij, T., and Spaan, J. A. (1991). Influence of pressure alterations on tone and vasomotion of isolated mesenteric small arteries of the rat. J. Physiol. 436, 371-383.
16. Wang, M. H., Brand-Schieber, E., Zand, B. A., Nguyen, X., Falck, J. R., Balu, N., and Schwartzman, M. L. (1998). Cytochrome P450-derived arachidonic acid metabolism in the rat kidney: Characterization of selective inhibitors. J. Pharmacol. Exp. Ther. 284, 966-973.
17. Wang, M. H., Zhang, F., Marji, J., Zand, B. A., Nasjletti, A., and Laniado-Schwartzman, M. (2001). CYP4Al antisense oligonucleotide reduces mesenteric vascular reactivity and blood pressure in SHR. Am. J. Physiol. Regul. Integr. Comp. Physiol. 280, R255-261.
18. Wesselman, J. P., Schubert, R., VanBavel, E. D., Nilsson, H., and Mulvany, M. J. (1997). KCa-channel blockade prevents sustained pressure-induced depolarization in rat mesenteric small arteries. Am. J. Physiol. 272, H2241-2249.
19. Zou, A. P., Fleming, J. T., Falck, J. R., Jacobs, E. R., Gebremedhin, D., Harder, D. R., and Roman, R. J. (1996). 20-HETE is an endogenous inhibitor of the large-conductance Ca(2+)-activated K+ channel in renal arterioles. Am. J. Physiol. 270, R228-237.