The soluble form of the membrane-bound transferrin homologue, melanotransferrin, inefficiently donates iron to cells via nonspecific internalization and degradation of the protein

European Journal of Biochemistry

Volumn 269, Issue 18, 2002, Pages 4435-4445

  Food, Michael R ^a   Sekyere, Eric O ^a   Richardson, Des R ^a,b  

^a HEART RESEARCH INSTITUTE   (Australia)

^b CHILDREN S CANCER INSTITUTE AUSTRALIA FOR MEDICAL RESEARCH   (Australia)

Author keywords

Iron; Iron uptake; Melanotransferrin; Transferrin; Transferrin receptor

Indexed keywords

IODINE 125; IRON 59; IRON BINDING PROTEIN; MELANOTRANSFERRIN; TRANSFERRIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING KINETICS; BINDING SITE; CELL TYPE; CHO CELL; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; INTERNALIZATION; IRON TRANSPORT; ISOTOPE LABELING; MELANOMA CELL; MEMBRANE BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN INTERACTION; SEQUENCE HOMOLOGY; SOLUBILITY;

BINDING SITES; HUMANS; IODINE; IRON; LIGANDS; NEOPLASM PROTEINS; TRANSFERRIN; TUMOR CELLS, CULTURED;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0036381706     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2002.03140.x     Document Type: Article

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