Inhibition by female sex steroids of peristalsis in the guinea pig small intestine

Digestion

Volumn 65, Issue 4, 2002, Pages 213-219

  Heinemann, Akos ^a   Pieber, Doris ^a   Holzer, Peter ^a  

^a UNIVERSITY OF GRAZ   (Austria)

Author keywords

Enteric nervous system; Estradiol; Intestinal peristalsis; Intestinal smooth muscle; Mifepristone; Progesterone; Steroids

Indexed keywords

5 AMINOVALERYLSUBSTANCE P [7-11][9 PROLINE 10 (N METHYLLEUCINE)]; APAMIN; CHOLECYSTOKININ OCTAPEPTIDE; CHOLESTEROL; ESTRADIOL; HYDROCORTISONE; MIFEPRISTONE; N(G) NITROARGININE METHYL ESTER; NALOXONE; NITRIC OXIDE SYNTHASE INHIBITOR; OPIATE ANTAGONIST; PROGESTERONE; PURINE ANTAGONIST; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; SEX HORMONE; SURAMIN; TACHYKININ RECEPTOR AGONIST; TESTOSTERONE;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GUINEA PIG; ILEUM CONTRACTION; INTESTINE MOTILITY; INTESTINE PRESSURE; MALE; MUSCLE CONTRACTILITY; NONHUMAN; PERISTALSIS; PRIORITY JOURNAL; SMALL INTESTINE;

ANIMALS; ESTRADIOL; FEMALE; GONADAL STEROID HORMONES; GUINEA PIGS; INTESTINE, SMALL; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; NITRIC OXIDE SYNTHASE; PERISTALSIS; PROGESTERONE; SEX FACTORS; STEROIDS;

EID: 0036381453     PISSN: 00122823     EISSN: None     Source Type: Journal    
DOI: 10.1159/000063820     Document Type: Article

References (23)

1. Baron TH, Ramirez B, Richter JE: Gastrointestinal motility disorders during pregnancy. Ann Intern Med 1993;118:366-375.
2. Chen TS, Doong ML, Chang FY, Lee SD, Wang PS: Effects of sex steroid hormones on gastric emptying and gastrointestinal transit in rats. Am J Physiol 1995;268:G171-G176.
3. Mathias JR, Clench MH: Relationship of reproductive hormones and neuromuscular disease of the gastrointestinal tract. Dig Dis 1998; 16:3-13.
4. Fontaine J, Seaman I, Famaey JP, Reuse J: Inhibitory effects of sexual steroidal hormones on the responses of the isolated guinea-pig ileum to acetylcholine and histamine. Arch Int Pharmacodyn Ther 1977;227:233-237.
5. Bielefeldt K, Waite L, Abboud FM, Conklin JL: Nongenomic effects of progesterone on human intestinal smooth muscle cells. Am J Physiol 1996;271:G370-G376.
6. Oh ST, Yedidag E, Bielefeldt K: Differential effects of progesterone and its analogues on the contractility of the murine jejunum in vitro. J Surg Res 1998;75:1-5.
7. Waterman SA, Tonini M, Costa M: The role of ascending excitatory and descending inhibitory pathways in peristalsis in the isolated guinea-pig small intestine. J Physiol (Lond) 1994;481: 223-232.
8. Furness JB, Kunze WA, Bertrand PP, Clerc N, Bornstein JC: Intrinsic primary afferent neurons of the intestine. Prog Neurobiol 1998;54: 1-18.
9. Tonini M, Costa M, Brookes SJ, Humphreys CM: Dissociation of the ascending excitatory reflex from peristalsis in the guinea-pig small intestine. Neuroscience 1996;73:287-297.
10. Holzer P, Lippe IT, Tabrizi AL, Lenard L Jr, Bartho L: Dual excitatory and inhibitory effect of nitric oxide on peristalsis in the guinea pig intestine. J Pharmacol Exp Ther 1997;280:154-161.
11. Heinemann A, Holzer P: Stimulant action of pituitary adenylate cyclase-activating peptide on normal and drug-compromised peristalsis in the guinea-pig intestine. Br J Pharmacol 1999;127:763-771.
12. Holzer P, Lembeck F, Donnerer J: Caerulein, substance P, serotonin and cholinomimetics induce rhythmic contractions of the intestinal circular muscle. Arch Pharmacol 1980;312:131-137.
13. Crist JR, He, XD, Goyal RK: Both ATP and the peptide VIP are inhibitory neurotransmitters in guinea-pig ileum circular muscle. J Physiol (Lond) 1992;447:119-131.
14. Bültmann R, Dudeck O, Starke K: Evaluation of P2 receptor antagonists at two relaxation-mediating P2 receptors in guinea-pig taenia coli. Arch Pharmacol 1996;353:445-451.
15. B receptors. Gastroenterology 2000;119:80-88.
16. Barthó L, Holzer P, Lembeck F, Lippe IT, Setnikar I: Evaluation of a new and potent cholecystokinin antagonist on motor responses of the guinea-pig intestine. Br J Pharmacol 1987;90:753-761.
17. 1 receptor agonists in the guinea-pig small intestine. Neurogastroenterol Motil 2000;12:197-204.
18. Hagan RM, Ireland SJ, Jordan CC, Beresford IJ, Deal MJ, Ward P: Receptor-selective, peptidase-resistant agonists at neurokinin NK-1 and NK-2 receptors: New tools for investigating neurokinin function. Neuropeptides 1991;19:127-135.
19. Tischkau SA, Ramirez VD: A specific membrane binding protein for progesterone in rat brain: Sex differences and induction by estrogen. Proc Natl Acad Sci USA 1993;90:1285-1289.
20. Van de Wiele RL, Dyrenfurth I: Gonadotropin-steroid interrelationships. Pharmacol Rev 1973;25:189-207.
21. Van Thiel DH, Gavaler JS, Joshi SN, Sara RK, Stremple J: Heartburn of pregnancy. Gastroenterology 1977;72:666-668.
22. Glasier A, Thong KJ, Dewar M, Mackie M, Baird DT: Mifepristone (RU 486) compared with high dose estrogen and progestogen for emergency postcoital contraception. N Engl J Med 1992;327:1041-1044.
23. El-Refaey H, Rajasekar D, Abdalla M, Calder L, Templeton A: Induction of abortion with mifepristone (RU 486) and oral or vaginal misoprostol. N Engl J Med 1995;332:983-987.