Evaluation of P2-purinoceptor antagonists at two relaxation-mediating P2-purinoceptors in guinea-pig taenia coli

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 353, Issue 4, 1996, Pages 445-451

  Bültmann, Ralph ^a   Dudeck, Oliver ^a   Starke, Klaus ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

, methylene ATP; Ecto nucleotidases; Evans blue; Guinea pig taenia coli; iso PPADS; P2 purinoceptors; P2y purinoceptor; Suramin; XAMR0721

Indexed keywords

EVANS BLUE; PURINE RECEPTOR; PURINERGIC RECEPTOR AFFECTING AGENT; PYRIDOXAL 5 PHOSPHATE; SURAMIN; TRYPAN BLUE; UNCLASSIFIED DRUG; XAMR 0721; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ANTITHROMBOCYTIC AGENT; CARBACHOL; DRUG DERIVATIVE; NORADRENALIN; PURINE P2 RECEPTOR; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; PYRIDOXAL PHOSPHATE-6-AZOPHENYL-2',4'-DISULFONIC ACID;

ANIMAL TISSUE; ARTICLE; COLON TENIA; GUINEA PIG; NONHUMAN; RECEPTOR BINDING; ANIMAL; CHEMISTRY; COLON; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; FEMALE; MALE; MUSCLE RELAXATION;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; CARBACHOL; COLON; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GUINEA PIGS; MALE; MUSCLE RELAXATION; NOREPINEPHRINE; PLATELET AGGREGATION INHIBITORS; PYRIDOXAL PHOSPHATE; RECEPTORS, PURINERGIC P2; SURAMIN;

EID: 0029670212     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Arunlakshana O, Schild HO (1959) Some quantitative uses of drug antagonists. Br J Pharmacol 14:48-58
2. 2Y-purinoceptors. Br J Pharmacol 113: 614-620
3. 2X-purinoceptors in rat vas deferens. Naunyn-Schmiedeberg's Arch Pharmacol 348 :684-687
4. 2-purinoceptor antagonists discriminate three contraction-mediating receptors for ATP in rat vas deferens. Naunyn-Schmiedeberg's Arch Pharmacol 349:74-80
5. 2Y-selective purinoceptor antagonist and an inhibitor of ecto-nucleotidase. Naunyn-Schmiedeberg's Arch Pharmacol 352:477-482
6. 2-purinoceptors in guinea-pig taenia coli. Naunyn-Schmiedeberg's Arch Pharmacol 350:R2
7. 2X-purinoceptors in rat vas deferens. Br J Pharmacol 113:349-354
8. Bültmann R, Driessen B, Gonçalves J, Starke K (1995) Functional consequences of inhibition of nucleotide breakdown in rat vas deferens: a study with Evans blue. Naunyn-Schmiedeberg's Arch Pharmacol 351:555-560
9. 2-purinoceptor? Gen Pharmacol 16:433-440
10. 2Y-purinoceptor. Br J Pharmacol 89:857P
11. 2Y subtypes. Drug Dev Res 31:206-219
12. Connolly GP (1995) Differentiation by pyridoxal 5-phosphate, PPADS and IsoPPADS between responses mediated by UTP and those evoked by α,α-methylene-ATP on rat sympathetic ganglia. Br J Pharmacol 114:727-731
13. 2X-purinoceptor ligands. Br J Pharmacol 113:1432-1438
14. 2 Receptor: subclassification and structure-activity relationships. Drug Dev Res 28:244-252
15. Den Hertog A, Pielkenrood J, Ras R, van den Akker J (1984) The contribution of calcium and potassium to the α-action of adrenaline on smooth muscle cells of the portal vein, pulmonary artery and taenia coli of the guinea-pig. Eur J Pharmacol 98:223-234
16. 2-purinoceptor response in smooth muscle cells of guinea-pig taenia coli. Eur J Pharmacol 166:531-534
17. 2-adrenoceptor-mediated modulation in guinea-pig vas deferens. Naunyn-Schmiedeberg's Arch Pharmacol 348:358-366
18. 2-purinoceptors in guinea-pig taenia coli. Naunyn-Schmiedeberg's Arch Pharmacol 351:107-110
19. Furchgott RF (1972) The classification of adrenoceptors (adrenergic receptors). An evaluation from the standpoint of receptor theory. In: Blaschko H, Muscholl E (eds) Catecholamines. Handbook of experimental pharmacology, vol 33. Springer, Berlin Heidelberg New York, pp 283-335
20. Hourani SMO, Chown JA (1989) The effects of some possible inhibitors of ectonucleotidases on the breakdown and pharmacological effects of ATP in the guinea-pig urinary bladder. Gen Pharmacol 20:413-416
21. 2-purinoceptor antagonist, suramin, on human platelet aggregation induced by adenosine 5′-diphosphate. Br J Pharmacol 105:453-457
22. 2-purinoceptor agonists and purinergic nerve stimulation in the guinea-pig urinary bladder and taenia coli. Br J Pharmacol 99:617-621
23. 2-purinoceptor subtypes - an update. Arch Int Pharmacodyn 303:30-50
24. 2X purinoceptors in rat vas deferens. Eur J Pharmacol 263:301-309
25. 2X-receptors in the rabbit isolated ear artery. Br J Pharmacol 101:645-649
26. Motulsky HJ, Ransnas LA (1987) Fitting curves to data using nonlinear regression: a practical and nonmathematical review. FASEB J 1:365-374
27. Piper AS, Hollingsworth M (1995) The purinoceptors of the guinea-pig isolated taenia coli. Eur J Pharmacol 280:125-134
28. 2 purinoceptor antagonist properties of pyridoxal-5-phosphate. Eur J Pharmacol 259:295-300
29. Trezise DJ, Kennedy I, Humphrey PPA (1994b) The use of antagonists to characterize the receptors mediating depolarization of the rat isolated vagus nerve by α,β-methylene adenosine 5′-triphosphate. Br J Pharmacol 112:282-288
30. 2 purinoceptors. Eur J Pharmacol 268:1-7
31. von Kügelgen I, Bültmann R, Starke K (1990) Interaction of adenine nucleotides, UTP and suramin in mouse vas deferens: suramin-sensitive and suramin-insensitive components in the contractile effect of ATP. Naunyn-Schmiedeberg's Arch Pharmacol 342:198-205
32. Waud DR (1976) Analysis of dose-response relationships. In: Narahashi T, Bianchi CP (eds) Advances in general and cellular pharmacology, vol 1. Plenum, New York London, pp 145-178
33. 2-purinoceptor. Eur J Pharmacol 129:217-224
34. 2y-purinoceptors and nucleotide receptors linked to phospholipase C. Br J Pharmacol 108:689-693
35. Windscheif U, Pfaff O, Ziganshin AU, Hoyle CHV, Bäumert HG, Mutschler E, Burnstock G, Lambrecht G (1995) Inhibitory action of PPADS on relaxant responses to adenine nucleotides or electrical field stimulation in guinea-pig taenia coli and rat duodenum. Br J Pharmacol 115:1509-1517