-
1
-
-
0010456673
-
Pharmacophore definition and 3D QSAR study on structurally diverse prostacyclin receptor agonist
-
submitted
-
Stoll, F., Liesener, S., Hohlfeld, T. et al., Pharmacophore definition and 3D QSAR study on structurally diverse prostacyclin receptor agonist, Mol. Pharmacol. (submitted)
-
Mol. Pharmacol.
-
-
Stoll, F.1
Liesener, S.2
Hohlfeld, T.3
-
2
-
-
0010497676
-
In silico HTS for new drug candidates
-
Ghosh, R., Höltje, H.-D., In silico HTS for new drug candidates, CHEManager: Screening, Trends Drug Discov. 3, 22 (2002)
-
(2002)
CHEManager: Screening, Trends Drug Discov.
, vol.3
, pp. 22
-
-
Ghosh, R.1
Höltje, H.-D.2
-
3
-
-
0010525989
-
Development of a Cytochrome P450 2A5 model, 13
-
Düsseldorf
-
Stahl, G., Höltje, H.-D., Development of a Cytochrome P450 2A5 model, 13. European Symposium QSAR 2000, Düsseldorf
-
(2000)
European Symposium QSAR
-
-
Stahl, G.1
Höltje, H.-D.2
-
5
-
-
0010493302
-
Prediction of the formation of glassy solid solutions of drugs in sugar alcohols
-
submitted
-
Langner, M., Höltje, M., Urbanetz, N. A. et al., Prediction of the formation of glassy solid solutions of drugs in sugar alcohols, Int. J. Pharm. (submitted)
-
Int. J. Pharm.
-
-
Langner, M.1
Höltje, M.2
Urbanetz, N.A.3
-
6
-
-
0021871375
-
A computational procedure for determining energetically favourable binding sites on biologically important macromolecules
-
Goodford, P. J., A computational procedure for determining energetically favourable binding sites on biologically important macromolecules, J. Med. Chem. 28, 849 (1985)
-
(1985)
J. Med. Chem.
, vol.28
, pp. 849
-
-
Goodford, P.J.1
-
7
-
-
0034604451
-
Crystal structure of rhodopsin: A G-protein coupled receptor
-
Palczewski, K., Kumasaka, T., Hori, T. et al., Crystal structure of rhodopsin: A G-protein coupled receptor, Science 289, 739 (2000)
-
(2000)
Science
, vol.289
, pp. 739
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
-
8
-
-
0031052398
-
Functional interaction of the carboxylic acid group of agonists and the arginine residue of the seventh transmembrane domain of prostaglandin E receptor EP3 subtype
-
Chang, C., Negishi, M., Nishigaki, N. et al., Functional interaction of the carboxylic acid group of agonists and the arginine residue of the seventh transmembrane domain of prostaglandin E receptor EP3 subtype, Biochem. J. 322, 597 (1997)
-
(1997)
Biochem. J.
, vol.322
, pp. 597
-
-
Chang, C.1
Negishi, M.2
Nishigaki, N.3
-
9
-
-
0031663772
-
A single amino-acid substitution in the EP2 prostaglandin receptor confers responsiveness to prostacyclin analogs
-
Kedzie, K. M., Donello, J. E., Krauss, H. et al., A single amino-acid substitution in the EP2 prostaglandin receptor confers responsiveness to prostacyclin analogs, Mol. Pharmacol. 54, 584 (1998)
-
(1998)
Mol. Pharmacol.
, vol.54
, pp. 584
-
-
Kedzie, K.M.1
Donello, J.E.2
Krauss, H.3
-
10
-
-
0008951090
-
Combigen: A novel software package for the rapid generation of virtual combinatorial libraries
-
H.-D. Höltje, W. Sippl (eds.), Prous Science, Barcelona
-
Wolber, G., Langer, T., Combigen: A novel software package for the rapid generation of virtual combinatorial libraries, in: Rational Approaches to Drug Design, H.-D. Höltje, W. Sippl (eds.), pp. 390-399, Prous Science, Barcelona (2000)
-
(2000)
Rational Approaches to Drug Design
, pp. 390-399
-
-
Wolber, G.1
Langer, T.2
-
11
-
-
0032149905
-
Feature trees: A new molecular similarity measure based on the tree matching
-
Rarey, M., Dixon, J. S., Feature trees: A new molecular similarity measure based on the tree matching, J. Comp.-Aided Mol. Des. 12, 471 (1998)
-
(1998)
J. Comp.-Aided Mol. Des.
, vol.12
, pp. 471
-
-
Rarey, M.1
Dixon, J.S.2
-
12
-
-
0030599010
-
A fast flexible docking method using incremental construction algorithm
-
Rarey, M., Kramer, B., Lengauer, T. et al., A fast flexible docking method using incremental construction algorithm, J. Mol. Biol. 261, 470 (1996)
-
(1996)
J. Mol. Biol.
, vol.261
, pp. 470
-
-
Rarey, M.1
Kramer, B.2
Lengauer, T.3
-
13
-
-
0033970047
-
Mammalian microsomal cytochrome P450 monooxygenase: Structural adaptations for membrane binding and functional diversity
-
Williams. P. A., Cosme, J., Sridhar, V. et al., Mammalian microsomal cytochrome P450 monooxygenase: Structural adaptations for membrane binding and functional diversity, Mol. Cell. 5, 121 (2000)
-
(2000)
Mol. Cell.
, vol.5
, pp. 121
-
-
Williams, P.A.1
Cosme, J.2
Sridhar, V.3
-
14
-
-
0027475221
-
Engineering mouse P450coh to a novel corticosterone 15α-hydroxylase and modeling steroid-binding orientation in the substrate pocket
-
Iwasaki, M., Darden, T. A., Pedersen, L. G. et al., Engineering mouse P450coh to a novel corticosterone 15α-hydroxylase and modeling steroid-binding orientation in the substrate pocket, J. Biol. Chem. 268, 759 (1993)
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 759
-
-
Iwasaki, M.1
Darden, T.A.2
Pedersen, L.G.3
-
15
-
-
0033954256
-
The protein data bank
-
Berman, H. M., Westbrook, J., Feng, Z. et al., The protein data bank, Nucleic Acids Res. 28, 235 (2000)
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 235
-
-
Berman, H.M.1
Westbrook, J.2
Feng, Z.3
-
16
-
-
0016025821
-
A method for estimating both the solubility parameters and molar volumes of liquids
-
Fedors, R. F., A method for estimating both the solubility parameters and molar volumes of liquids, Polym. Eng. Sci. 14, 147 (1974)
-
(1974)
Polym. Eng. Sci.
, vol.14
, pp. 147
-
-
Fedors, R.F.1
|