Alterations in membrane-associated CD14 expression and the simultaneous liberation of soluble CD14 fragment in adherent macrophages mediated by a leukocyte carboxyl/aspartate protease

Journal of Endotoxin Research

Volumn 8, Issue 4, 2002, Pages 273-283

  Coyne, C P ^a   Howell, Trey ^a,d   Smodlaka, Hrvoje ^a   Willetto, Carla ^a,c   Fenwick, Brad W ^b   Chenney, Erle ^a  

^a MISSISSIPPI STATE UNIVERSITY   (United States)

^b KANSAS STATE UNIVERSITY   (United States)

^c Ilisagvik College   (United States)

^d UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CALCIMYCIN; CATHEPSIN D; CD14 ANTIGEN; CYSTEINE; ELASTASE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; HEMOGLOBIN; LEUKOCYTE ENZYME; METALLOPROTEINASE; PEPSTATIN; PROTEINASE; PROTEINASE INHIBITOR; THIOL;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN STRUCTURE; ARTICLE; BINDING AFFINITY; CELL ADHESION; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME ISOLATION; FEMALE; MACROPHAGE ACTIVATION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN DEGRADATION; PROTEIN HYDROLYSIS;

ANIMALS; ANTIGENS, CD14; ASPARTIC ENDOPEPTIDASES; CALCIMYCIN; CATHEPSIN D; CATTLE; CELL ADHESION; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MACROPHAGE ACTIVATION; MACROPHAGES; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; PANCREATIC ELASTASE; PEPTIDE FRAGMENTS;

ANIMALIA;

EID: 0036376210     PISSN: 09680519     EISSN: None     Source Type: Journal    
DOI: 10.1179/096805102125000489     Document Type: Article

References (53)

1. LPS mediated production of IL-1, PGE2 and PGF2alpha from term dicidua involves tumor necrosis factor and tumor necrosis factor receptor p55
2. Shedding of tumor necrosis factor receptors by activated human neutrophils
3. Biochemical mechanisms of soluble TNFR fragment 'shedding' by activated populations of bovine neutrophils
4. Identification of the proteolytic enzyme which cleaves human p75 receptor in-vivo
5. Human neutrophil elastase release and ligand-binding fragment from the 75-kDa tumor necrosis factor (TNF) receptor
6. A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor
7. A metalloproteinase inhibitor blocks the shedding of soluble cytokine receptors and processing of transmembrane cytokine receptors; in human monocytic cells
8. Molecular mechanisms of TNFR type II (75-kDa) 'shedding' in adherent macrophages
9. Characterization of a relationship between the T-lymphocyte derived differentiation inducing factor (DIF) and lymphotoxin: A common receptor system for DIF, lymphotoxin, and tumour necrosis factor down-regulated by phorbol diesters
10. Interleukin type II receptor: A decoy target for IL-1 that is regulated by IL-4
11. Biochemical mechanisms influencing membrane-associated IL-1 RII (60-kDa decoy) receptors in populations of adherent macrophages and vascular endothelium
12. Characterization of the soluble murine IL-2R and estimation of its affinity for IL-2
13. The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane-bound forms
14. Molecular cloning and expression of the murine interleukin-5 receptor
15. Soluble cytokine receptors are present in normal human urine
16. Purification of soluble cytokine receptors from normal human urine by ligand-affinity and immunoaffinity chromatography
17. The soluble interleukin-6 receptor is generated by shedding
18. Biochemical alteration of membrane-associated IL-6 RI (80-kDa) in adherent macrophages and vascular endothelium
19. Cloning of the human and murine interleukin-7 receptors: Demonstration of a soluble form and homology to a new receptor superfamily
20. Expression cloning of the murine and interleukin-9 receptor DNAs
21. TNF-alpha, unlike other pro- and anti-inflammatory cytokines, induces rapid release of the IL-1 type II decoy receptor in human myelomonocytic cells
22. Interleukin-4 (IL-4) induces down-modulation and shedding of the p55 tumor necrosis factor receptor and inhibits TNF-alpha's effect on rheumatoid synovial fibroblasts
23. Characteristics of CD14 shedding from human monocytes. Evidence for the competition of soluble CD14 (sCD14) with CD14 receptors for lipopolysaccharide (LPS) binding
24. Shedding as a mechanism of down-modulation of CD14 on stimulated human monocytes
25. Identification, purification, and characterization of truncated forms of the human nerve growth factor receptor
26. Monocyte cell necrosis is mediated by potassium depletion and caspase-like proteases
27. Macrophages rapidly internalize their tumor necrosis factor receptors in response to bacterial lipopolysaccharides
28. Plasminogen activator production by bovine milk macrophages and blood monocytes
29. Bacterial lipopolysaccharide induces release of tumor necrosis factor-alpha from bovine peripheral blood monocytes, and alveolar macrophages in-vitro
30. Cytokine (IL-8, IL-6, TNF-alpha) and soluble TNF receptor-I release from human peripheral blood monocytes after respiratory syncytial virus infection
31. Equine CD14 and LBP isolation and characterization
32. Lipopolysaccharide-mediated induction of the bovine interleukin-6 gene in monocytes requires both NF-κB and C/EBP binding sites
33. Isolation of cathepsin-D using three-phase partitioning in t-butanol/water/ammonium sulfate and pepstatin-A affinity chromatography
34. An improved cathepsin-D substrate and assay procedure
35. A role for the immunoglobulin-like domain of the human IL-6 receptor. Intracellular protein transport and shedding
36. Role of different dialysis membranes in the release of interleukin-6-soluble receptor in uremic patients
37. Factors influencing the effect of the soluble IL-6 receptor on IL-6 responses in HepG2 hepatocytes
38. Analysis of the production of soluble ICAM-1 molecules by human cells
39. Inactivation of recombinant human tumor necrosis factor alpha by proteolytic enzymes released from stimulated human neutrophils
40. A metalloprotease inhibitor blocks the shedding of soluble cytokine receptors and processing of transmembrane cytokine precursors in human monocytic cell
41. Synthesis and secretion of procathepsin-B and cystatin-C by human bronchial epithelial cells in vitro: Modulation of cathepsin-B activity by neutrophil elastase
42. Human sputum cathepsin-B degrades proteoglycan, is inhibited by alpha-2-macroglobulin and is modulated by neutrophil elastase cleavage of cathepsin-B precursor and cystatin-C
43. In-vitro activation of pro-cathepsin-B by three serine proteinases: Leukocyte elastase, cathepsin-G and the urokinase-type plasminogen activator
44. Analysis of where and which types of proteinases participate in lysosomal proteinases processing using bafilomycin A1 and Helicobacter pylori Vac A toxin
45. Evolution in the structure and function of carboxyl proteases
46. Cathepsin-D in human endometrium: Induction by progesterone and potential value as a tumor marker
47. Mechanisms and kinetics of procathepsin-D activation
48. Proteolytic activation of human procathepsin-D
49. Inhibition of aspartic proteases by pepstatin and 3-methylstatine derivatives of pepstatin. Evidence for collected-substrate enzyme inhibition
50. Identification of latent procathepsins B and L in microsomal lumen: Characterization of enzymatic activation and proteolytic processing in-vitro
51. Tumor necrosis factor soluble receptor 75: The principal receptor form released by human alveolar macrophages and monocytes in the presence of interferon (gamma)
52. Tumor necrosis factor alpha and interleukin-1 alpha stimulate late shedding of p75 receptors but not p55 TNF receptors from human monocytes
53. Differential sensitivity to Escherichia coli infection in mice lacking tumor necrosis factor p55 or interleukin-1 p80 receptors