Difluoromethylation reactions of ethyl pyruvate with the TDAE - A mild approach to the synthesis of 3,3-difluoro-2-hydroxy-2-methyl-4-oxo-butyric ethyl esters derivatives

Synlett

Volumn , Issue 9, 2002, Pages 1541-1543

  Médebielle, Maurice ^a   Kato, Katsuya ^b   Dolbier Jr , William R ^c  

^a UNIVERSITÉ LYON 1   (France)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c UNIVERSITY OF FLORIDA   (United States)

Author keywords

Electron transfer; Ethyl pyruvate; Fluorine; Nucleophilic additions; Tetrakis(dimethylamino)ethylene

Indexed keywords

BUTYRIC ACID ETHYL ESTER; ESTER DERIVATIVE; ETHYLENE DERIVATIVE; PYRUVIC ACID; TETRAKIS(DIMETHYLAMINO)ETHYLENE; UNCLASSIFIED DRUG;

ARTICLE; FLUORINATION; METHYLATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS;

EID: 0036373839     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-33517     Document Type: Article

References (19)