Decreased phorbol ester binding in the parahippocampal gyrus from subjects with schizophrenia is not associated with changes in protein kinase C

Molecular Psychiatry

Volumn 7, Issue 7, 2002, Pages 683-688

  Scarr, E ^a   Pavey, G ^a   Robinson, P J ^b   Opeskin, K ^a   Copolov, D L ^a   Dean, B ^a  

^a FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^b CHILDREN'S MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Human; Mental illness; Postmortem; Second messenger; Temporal lobe

Indexed keywords

PHORBOL DIBUTYRATE; PHORBOL ESTER; PROTEIN KINASE C; RADIOLIGAND;

ADULT; AGED; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN TISSUE; LIGAND BINDING; MALE; PRIORITY JOURNAL; SCHIZOPHRENIA; SUBICULUM;

ADULT; AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; CARCINOGENS; FEMALE; HUMANS; MALE; MIDDLE AGED; PARAHIPPOCAMPAL GYRUS; PHORBOL 12,13-DIBUTYRATE; PROTEIN KINASE C; RADIOLIGAND ASSAY; SCHIZOPHRENIA; SECOND MESSENGER SYSTEMS; TRITIUM;

EID: 0036366099     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4001065     Document Type: Article

References (23)

1. Changes in protein kinase C and adenylate cyclase in the temporal lobe from subjects with schizophrenia
2. Neither protein kinase C nor adenylate cyclase are altered in the striatum from subjects with schizophrenia
3. Mechanism of action of the phorbol ester tumor promoters: Specific receptors for lipophilic ligands
4. Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters
5. Synergistic functions of phorbol ester and calcium in serotonin release
6. The molecular heterogeneity of protein kinase C and its implications for cellular regulation
7. Effect of phorbol esters on protein kinase C-zeta
8. Neuroleptic equivalence
9. Tissue pH as an indicator of mRNA preservation in human postmortem brain
10. Protein kinase C in the postmortem brain of teenage suicide victims
11. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
12. Effects of treatment with haloperidol, chlorpromazine, and clozapine on protein kinase C (PKC) and phosphoinositide-specific phospholipase C (PI-PLC) activity and on mRNA and protein expression of PKC and PLC isozymes in rat brain
13. Treatment with haloperidol or clozapine causes changes in dopamine receptors but not adenylate cyclase or protein kinase C in the rat forebrain
14. Close similarity of baculo-virus-expressed n-chimaerin and protein kinase C alpha as phorbol ester receptors
15. Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release
16. Human brain n-chimaerin cDNA encodes a novel phorbol ester receptor
17. The N-terminal region of n-chimaerin allows lipid modulation of the C-terminal p21rac-GTPase activating domain
18. Bcr encodes a GTPase-activating protein for p21rac
19. Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles
20. A glutamatergic deficiency model of schizophrenia
21. Cloning of a novel gene in the human kidney homologous to rat munc13s: Its potential role in diabetic nephropathy