Reduction of exposure to laboratory animal allergens in a research laboratory

Annals of Occupational Hygiene

Volumn 46, Issue 1, 2002, Pages 61-68

  Thulin, Hans ^a   Björkdahl, Marianne ^b   Karlsson, Anne Sophie ^c   Renström, Anne ^c  

^a Box 941   (Sweden)

^b Active Biotech Research AB   (Sweden)

^c NATIONAL INSTITUTE FOR WORKING LIFE   (Sweden)

Author keywords

Exposure; Laboratory animal allergy; Mouse; Task

Indexed keywords

ALLERGIES; OCCUPATIONAL RISKS; RESPIRATORY SYSTEM; VACUUM CLEANERS; ANIMALS; CLEANING; LABORATORIES; MAMMALS; RESEARCH LABORATORIES; SURVEYS;

ANIMAL ALLERGENS;

RESEARCH LABORATORIES; ALLERGENS;

ALLERGEN; IMMUNOGLOBULIN E;

ARTICLE; CLINICAL ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL ANIMAL; HUMAN; LABORATORY; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; OCCUPATIONAL SAFETY; PRIORITY JOURNAL; VACUUM; AIR CONDITIONING; AIR POLLUTANT; ANIMAL; BLOOD; HYPERSENSITIVITY; LABORATORY PERSONNEL; MOUSE; QUESTIONNAIRE;

AIR POLLUTANTS, OCCUPATIONAL; ALLERGENS; ANIMALS; ANIMALS, LABORATORY; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; LABORATORY PERSONNEL; MICE; OCCUPATIONAL EXPOSURE; QUESTIONNAIRES; VENTILATION;

ENZYME LINKED IMMUNOSORBENT ASSAY; EXPOSURE; LABORATORY ANIMALS; MOUSE; PERSONAL EXPOSURES; REDUCTION STRATEGY; RESPIRATORY PROTECTION; TASK;

EID: 0036360383     PISSN: 00034878     EISSN: None     Source Type: Journal    
DOI: 10.1093/annhyg/mef022     Document Type: Article

References (19)

1. Gordon S, Tee RD, Lowson D, Wallace J, Newman Taylor AJ. (1992) Reduction of airborne allergenic urinary proteins from laboratory rats. Br J Ind Med; 49: 416-22.
2. Gordon S, Wallace J, Cook A, Tee RD, Newman Taylor AJ. (1997) Reduction of exposure to laboratory animal allergens in the workplace. Clin Exp Allergy; 27: 744-51.
3. Hastie N, Held W, Toole J. (1979) Multiple genes coding for the androgen regulated major urinary proteins of the mouse. Cell; 17: 449-57.
4. Heederik D, Venables KM, Malmberg P, Hollander A, Karlsson AS, Renstrom A, Doekes G, Nieuwenhijsen M, Gordon S. (1999) Exposure-response relationships for work-related sensitization in workers exposed to rat urinary allergens: results from a pooled study. J Allergy Clin Immunol; 103: 678-84.
5. Hollander A, Heederik D, Doekes G. (1997) Respiratory allergy to rats: exposure-response relationships in laboratory animal workers. Am J Respir Crit Care Med; 155: 562-7.
6. Hollander A, Heederik D, Doekes G, Kromhout H. (1998) Determinants of airborne rat and mouse urinary allergen exposure. Scand J Work Environ Health; 24: 228-35.
7. Hunskaar S, Fosse RT. (1990) Allergy to laboratory mice and rats: a review of the pathophysiology, epidemiology and clinical aspects. Lab Anim; 24: 358-74.
8. Jones RB, Kacergis JB, MacDonald MR, McKnight FT, Turner WA, Ohman JL, Paigen B. (1995) The effect of relative humidity on mouse allergen levels in an environmentaly controlled mouse room. Am Ind Hyg Assoc J; 56: 398-401.
9. Kacergis JB, Jones RB, Reeb CK, Turner WA, Ohman JL, Ardman MR, Paigen B. (1996) Air quality in an animal facility: particulates, ammonia, and volatile organic compounds. Am Ind Hyg Assoc J; 57: 634-40.
10. Lorusson JR, Moffat S, Ohman JL. (1986) Immunologic and biochemical properties of the major mouse urinary allergen. (Mus m 1). J Allergy Clin Immunol; 78: 928-37.
11. Platt-Mills TAE, Heymann PW, Longbottom JL, Wilkins SR. (1986) Airborne allergens associated with asthma: particle size carring dust mite and rat. J Allergy Clin Immunol; 77: 850-7.
12. Price JA, Longbottom JL. (1987) Allergy to mice. I. Identification of two major mouse allergens. (Ag 1 and Ag 3) and investigation of their possible origin. Clin Allergy; 17: 43-53.
13. Price JA, Longbottom JL. (1988) ELISA method for measurement of airborne levels of major laboratory animal allergens. Clin Allergy; 18: 95-107.
14. Rajka G. (1961) Ten cases of occupational hypersensitivity to laboratory animals. Acta Allergol; 16: 168-76.
15. Reeb-Whitaker CK, Harrison DJ, Jones RB, Kacergis JB, Mayers DD, Paigen B. (1999) Control strategies for aleroallergens in an animal facility. J Allergy Clin Immunol; 103: 139-46.
16. Renström A, Malmberg P, Larsson PH, Sundblad B-M. (1995) Allergic sensitization is associated with increased bronchial responsiveness: a prospective study of allergy to laboratory animals. Eur Respir J; 8: 1514-1519.
17. Renström A, Björing G, Höglund AU. (2001) Evaluation of individually ventilated cage systems for laboratory rodents: occupational health aspects. Lab Anim; 35: 42-50.
18. Sakaguchi M, Inouye S, Miyazawa H, Kamimura H, Kimura M, Yamazaki S. (1989) Particle size of airborne mouse crude and defined allergens. Lab Anim Sci; 39: 234-6.
19. Sorell AH, Gottesman J. (1957) Mouse allergy. Ann Allergy; 15: 662-3.