Determinants of airborne rat and mouse urinary allergen exposure

Scandinavian Journal of Work, Environment and Health

Volumn 24, Issue 3, 1998, Pages 228-235

  Hollander, Albert ^a   Heederik, Dick ^a   Doekes, Gert ^a   Kromhout, Hans ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Aeroallergens; Ambient air; Job title; Laboratory animals; Task

Indexed keywords

ALLERGEN;

AIR SAMPLING; AMBIENT AIR; ARTICLE; EXPERIMENTAL ANIMAL; FILTER; HUMAN; LABORATORY; OCCUPATIONAL ALLERGY; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HEALTH; PARTICLE SIZE; PRIORITY JOURNAL; TIME; URINE LEVEL; WORK ENVIRONMENT;

ANIMALIA;

EID: 0031875701     PISSN: 03553140     EISSN: None     Source Type: Journal    
DOI: 10.5271/sjweh.303     Document Type: Article

References (39)

1. Cockcroft A, Edwards J, McCarthy P, Andersson N. Allergy in laboratory animal workers. Lancet 1981;1:827-30.
2. Beeson MF, Dewdney JM, Edwards RG, Lee D, Orr RG. Prevalence and diagnosis of laboratory animal allergy. Clin Allergy 1983;13:433-42.
3. Bland SM, Levine MS, Wilson PD, Fox NL, Rivera JC. Occupational allergy to laboratory animals: an epidemiological study. J Occup Med 1986;28:1151-7.
4. Venables KM, Tee RD, Hawkins ER, Gordon DJ, Wale CJ, Farrer MN, et al. Laboratory animal allergy in a pharmaceutical company. Br J Ind Med 1988;45:660-6.
5. Kibby T, Powell G, Cromer J. Allergy to laboratory ani mals: a prospective and cross-sectional study. J Occup Med 1989;31:842-6.
6. Cullinan P, Lowson D, Nieuwenhuijsen MJ, Gordon S, Tee RD, Venables KM, et al. Work related symptoms, sensitisation, and estimated exposure in workers not previously exposed to laboratory rats. Occup Environ Med 1994;51:589-92.
7. Renström A, Malmberg P, Larsson K, Sundblad B-M, Larsson PH. Prospective study of laboratory-animal allergy: factors predisposing to sensilization and development of allergic symptoms. Allergy 1994;49:548-52.
8. Hollander A, Doekes G, Heederik D. Cat and dog allergy and total IgE as risk factors of laboratory animal allergy. J Allergy Clin Immunol 1996;98:545-54.
9. Hollander A, Heederik D, Doekes G. Respiratory allergy to rats: exposure-response relationships in laboratory animal workers. Am J Respir Crit Care Med. In press.
10. Kromhout H, Swuste P, Boleij JSM. Emperical modelling of chemical exposure in the rubber manufactering industry. Ann Occup Hyg 1994;38:3-22.
11. Preller L, Heederik D, Kromhout H, Boleij JSM, Tielen MJM. Determinants of dust and endotoxin exposure of pig farmers: development of a control strategy using empirical modelling. Ann Occup Hyg 1995;39:545-557.
12. Eisen EA, Smith TJ, Wegman DH, Louis TA, Froines J. Estimation of long term dust exposures in the Vermont granite sheds. Am Ind Hyg Assoc J 1984;45:89-94.
13. Preller L, Kromhout H, Heederik D, Tielen MJM. Modeling long-term average exposure in occupational exposure-response analysis. Scand J Work Environ Health 1995;21:504-12.
14. Smid T, Heederik D, Mensink G, Houba R, Boleij JSM. Exposure to dust, endotoxin and fungi in the animal feed industry. Am Ind Hyg Assoc J 1992;53:362-8.
15. Newman Taylor A, Longbottom JL, Pepys J. Respiratory allergy to urine proteins of rats and mice. Lancet 1977;2:847-9.
16. Schumacher MJ. Characterization of allergens from urine and pelts of laboratory mice. Mol Immunol 1980;17:1087-95.
17. Walls AF, Longbottom JL. Comparison of rat fur, urine, saliva, and other rat allergen extracts by skin testing,RAST, and RAST inhibition. J Allergy Clin Immunol 1985;75:242-51.
18. Lutsky I, Fink JN, Kidd J, Dahlberg MJE, Yuninger JW. Allergenic properties of rat urine and pelt extracts. J Allergy Clin Immunol 1985;75:279-84.
19. Gordon S, Tee RD, Newman Taylor AJ. Analysis of rat urine proteins and allergens by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting. J Allergy Clin Immunol 1993;92:298-305.
20. Gordon S, Tec RD, Lowson D, Wallace J, Newman Taylor AJ. Reduction of airborne allergenic urinary proteins from laboratory rats. Br J Ind Med 1992;49:416-422.
21. Ohman JL, Hagberg K, MacDonald MR, Jones RR, Paigen BJ, Kacergis JB. Distribution of airborne mouse allergen in a major mouse breeding facility. J Allergy Clin Immunol 1994;94:810-817.
22. Nieuwenhuijsen MJ, Gordon S, Harris J, Tee RD, Venables KM, Newman Taylor AJ. Determinants of airborne allergen exposure in an animal house. Occup Hyg 1995;1:317-324.
23. Platts-Mills TAE, Heyman PW, Longbottom JL, Wilkins SR. Airborne allergens associated with asthma: particle sizes carrying dust mite and rat allergens measured with a cascade impactor. J Allergy Clin Immunol 1986;77:850-857.
24. Jones RB, Kacergis JB, MacDonald MR, McKnight FT, Turner WA, Ohman JL, et al. The effect of relative humidity on mouse allergen levels in an environmentally controlled mouse room. Am Ind Hyg Assoc J 1995;56:398-401.
25. Swanson MC, Campbell AR, O'Hollaren MT, Reed CE. Role of ventilation, air filtration, and allergen production rate in determining concentrations of rat allergens in the air of animal quarters. Am Rev Respir Dis 1990;141:1578-81.
26. Kacergis JB, Jones RB, Reeb CK, Turner WA, Ohman JL, Ardman MR, et al. Air quality in an animal facility: particulates, ammonia, and volatile organic compounds. Am Ind Hyg Assoc J 1996;57:634-40.
27. Corn M, Esmen NA. Workplace exposure zones for classification of employees exposures to physical and chemical agents. Am Ind Hyg Assoc J 1979;40:47-57.
28. Mark D, Vincent JH. A new personal sampler for airborne total dust in workplaces. Ann Occup Hyg 1986;30:89-102.
29. Hollander A, van Run P, Spithoven J, Dockes G, Heederik D. Exposure of laboratory animal workers to airborne rat and mouse urinary allergens. Clin Exp Allergy. In press.
30. Price JA, Longbottom JL. ELISA method for measurement of airborne levels of major laboratory animal allergens. Clin Allergy 1988;18:95-107.
31. Nieuwenhuijsen MJ, Gordon S, Tee RD, Venables KM, McDonald JC, Newman Taylor AJ. Exposure to dust and rat urinary aeroallergens in research establishments. Occup Environ Med 1994;51:593-6.
32. Davies GE, Thompson AV, Rackham M. Estimation of airborne rat-derived antigens by ELISA. J Immunoassay 1983;4:113-26.
33. Eggleston PA, Newill CA, Ansari AA, Pustelnik A, Lou S, Evans III R, et al. Task-related variation in airborne concentrations of laboratory animal allergens: studies with RAT n I. J Allergy Clin Immunol 1989;84:347-52.
34. Vincent JH, Mark D, Miller B, Armbuster L, Ogden TL. Aerosol inhalability at higher wind speeds. J Aerosol Sci 1990;21:577-86.
35. Nieuwenhuijsen MJ, Gordon S, Harris JM, Tee RD, Venables KM, Newman Taylor AJ. Variation in rat urinary aeroallergen levels explained by differences in site, task and exposure group. Ann Occup Hyg 1995;39:819-25.
36. Edwards RG, Beeson MF, Dewdney JM. Laboratory animal allergy: the measurement of airborne urinary allergens and the effects of different environmental conditions. Lab Anim 1983;17:235-9.
37. Corn M, Koegel A, Hall T, Scott A, Newill C, Evans R. Characteristics of airborne particles associated with animal allergy in laboratory workers. Ann Occup Hyg 1988;32 suppl 1:435-46.
38. Sakaguchi M, Inouye S, Miyazawa H, Kamimura H, Kimura M, Yamazaki S. Particle size of airborne mouse crude and defined allergens. Lab Anim Sci 1989;39:234-6.
39. Lippmann M, Yeates DB, Albert RE. Deposition, retention, and clearance of inhaled particles. Br J Ind Med 1980;37:337-62.