Effect of a triclosan-containing toothpaste supplemented with 10% xylitol on mutans streptococci in saliva and dental plaque: A 6-month clinical study

Caries Research

Volumn 36, Issue 1, 2002, Pages 36-39

  Jannesson, L ^a   Renvert, S ^a   Kjellsdotter, P ^a   Gaffar, A ^c   Nabi, N ^c   Birkhed, D ^b  

^a KRISTIANSTAD UNIVERSITY   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c Oral Care Research and Development   (United States)

Author keywords

Mutans streptococci; Plaque; Saliva; Triclosan; Xylitol

Indexed keywords

ANTICARIES AGENT; COLGATE TOTAL; FLUORIDE; PLACEBO; TOOTHPASTE; TOPICAL ANTIINFECTIVE AGENT; TRICLOSAN; XYLITOL;

ADULT; ANALYSIS OF VARIANCE; ARTICLE; BACTERIAL COUNT; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG MIXTURE; FOLLOW UP; GROWTH, DEVELOPMENT AND AGING; HUMAN; MICROBIOLOGY; SALIVA; STATISTICS; STREPTOCOCCUS MUTANS; TOOTH PLAQUE;

ADULT; ANALYSIS OF VARIANCE; ANTI-INFECTIVE AGENTS, LOCAL; CARIOSTATIC AGENTS; COLONY COUNT, MICROBIAL; COMPLEX MIXTURES; DENTAL PLAQUE; DENTIFRICES; DOUBLE-BLIND METHOD; FLUORIDES; FOLLOW-UP STUDIES; HUMANS; PLACEBOS; SALIVA; STATISTICS; STREPTOCOCCUS MUTANS; TOOTHPASTE; TRICLOSAN; XYLITOL;

EID: 0036359235     PISSN: 00086568     EISSN: None     Source Type: Journal    
DOI: 10.1159/000057588     Document Type: Article

References (29)

1. Addy M, Jenkins S, Newcombe R: Toothpastes containing 0.3% and 0.5% triclosan. II Effects of single brushings on salivary bacterial counts Am J Dent 1989,2.215-219.
2. Birkhed D: Cariological aspects of xylitol and its use in chewing gum. Acta Odontol Scand 1994; 52:116-127.
3. Bratthall D: Immunofluorescent identification of Streptococcus mutans. Odontol Revy 1972;23: 181-196.
4. Cubells AB, Dalmau LB, Petrone ME, Chakins P, Volpe AR: The effect of a triclosan/copolymer/ fluoride dentifrice on plaque formation and gingivitis: A six-month clinical study. J Clin Dent 1991;2:63-69.
5. Cutress T, Howell PT, Finidori C, Abdullah F: Caries preventive effect of high fluoride and xylitol containing dentifrices. J Dent Child 1992;59: 313-318.
6. Deasy MJ, Singh SM, Rustogi KN, Petrone DM. Battista G. Petrone ME, Volpe AR: Effect of a dentifrice containing triclosan and a copolymer on plaque formation and gingivitis. Clin Prev Dent 1991;13:12-19.
7. Emilson CG: Prevalence of Streptococcus mutans with different colonial morphologies in human plaque and saliva Scand J Dent Res 1983;91: 26-32.
8. Emilson CG, Krasse B: Support for and implications of the specific plaque hypothesis. Scand J Dent Res 1985;93:96-104.
9. Gaffar A, Afflito J, Nabi N, Hereles S, Kruger I, Olsen S: Recent advances in plaque, gingivitis, tatar and caries prevention technology. Int Dent J 1994;44:63-70.
10. Gaffar A, Blake-Haskins JC, Sullivan R, Simone A, Schmidt R, Saunders F: Cariostatic effects of a xylitol/NaF dentifrice in vivo. Int Dent J 1998; 48:32-39.
11. Garcia-Godoy F, Garcia-Godoy F, DeVizio W, Volpe AR. Ferlauto RJ, Miller JM: Effect of a triclosan/copolymer/fluoride dentifrice on plaque formation and gingivitis. A 7-month clinical study. Am J Dent 1990;3(special issue): 15-26.
12. Giertsen E, Emberland H, Scheie AA: Effects of mouthrinses with xylitol and fluoride on dental plaque and saliva. Caries Res 1999;33:23-31.
13. Gold OG, Jordan HV. van Houte J A selective medium for the isolation of Streptococcus mutans. Arch Oral Biol 1973;18:1357-1364.
14. Jannesson L, Renvert S, Birkhed D: Effect of xylitol in an enzyme-containing dentifrice without sodium lauryl sulfate on mutans streptococci in vivo. Acta Odontol Scand 1997;55;212-216.
15. Lindhe J, Rosling B, Socransky SS, Volpe TR: The effect of a triclosan-containing dentifrice on established plaque and gingivitis. J Clin Periodontol 1993;20:327-334.
16. Lingström P, Lundgren F, Birkhed D, Takazoe I, Frostell G. Effects of frequent mouthrinses with palatinose and xyhtol on dental plaque. Eur J Oral Sci 1997;105:162-169.
17. Lobene RR, Battista GW, Petrone DM, Volpe AR, Petrone ME: Anticalculus effect of a fluoride dentifrice containing triclosan and a copolymer. Am J Dent 1990;3(special issue):47-49.
18. Lobene RR, Battista GW, Petrone DM. Volpe AR, Petrone ME: Clinical efficacy of an anticalculus fluoride dentifrice containing triclosan and a copolymer: A 6-month study. Am J Dent 1991;4:83-85.
19. Mäkinen KK: Xylitol-based caries prevention: Is there enough evidence for the existence of a specific xylitol effect? J Oral Dis 1998;4:226-230.
20. Mäkinen KK. Söderling E. Hart H, Lehtonen OP, Luukala T: Biochemical, microbiologic and clinical comparisons between two dentifrices that contain different mixtures of sugar alcohols. J Am Dent Assoc 1985;11:745-751.
21. Petersson L, Birkhed D, Gleerup A, Johansson M, Jönsson G: Caries-preventive effect of dentifrices containing various types and concentrations of fluorides and sugar alcohols. Caries Res 1991;25:74-79.
22. Renvert S, Birkhed D: Comparison between three triclosan dentifrices on plaque, gingivitis and salivary microflora. J Clin Periodontol 1995; 22:63-70.
23. Rosling B, Dahlén G, Volpe A, Furuichi Y, Ramberg P, Lindhe J: Effect of triclosan on the subgingival microbiota of periodontitis-susceptible subjects. J Clin Periodontol 1997;24:881-887.
24. Scheie AA, Fejerskov OB: Xylitol in caries prevention: What is the evidence for clinical efficacy? J Oral Dis 1998;4:268-278.
25. Sintes JL, Escalante C, Stewart B, McCool J, Carcia L, Volpe AR, Triol C: Enhanced anticaries efficacy of a 0.243% sodium fluoride/10% xylitol/ silica dentifrice: 3-year clinical results. Am J Dent 1995;8:231-235.
26. Svanberg M, Birkhed D: Effect on dentifrices containing either xylitol and glycerol OT sorbitol on mutans streptococci in saliva. Caries Res 1991; 25:449-453.
27. Syed SA, Loesche WJ: Survival of human dental plaque flora in various transport media. Appl Microbiol 1972;24:638-644.
28. Twetman S, Petersson L. Influence of xylitol in dentifrice on salivary microflora of preschool children at caries risk. Swed Dent J 1995;19: 103-108.
29. Wennerholm K, Arends J, Birkhed D, Ruben J, Emilson CG, Dijkman AG: Effect of xylitol and sorbitol in chewing-gums on mutans streptococci, plaque pH and mineral loss of enamel. Caries Res 1994;28:48-54.