Xylitol in caries prevention: What is the evidence for clinical efficacy?

Oral Diseases

Volumn 4, Issue 4, 1998, Pages 268-278

  Scheie, Anne Aamdal ^a   Fejerskov, O B ^b  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY OF AARHUS   (Denmark)

Author keywords

Dental caries; Dental plaque; Mutans streptococci; Polyols; Prophylaxis; Xylitol

Indexed keywords

ANTICARIES AGENT; POLYOL; SORBITOL; SWEETENING AGENT; XYLITOL;

BELIZE; CANADA; CHEWING GUM; CLINICAL TRIAL; DENTAL CARIES; DRUG EFFICACY; FINLAND; FRENCH POLYNESIA; HUMAN; HUNGARY; MOUTH HYGIENE; PRIORITY JOURNAL; REVIEW; STREPTOCOCCUS MUTANS; THAILAND; TOOTH PLAQUE; WORLD HEALTH ORGANIZATION;

EID: 0032425153     PISSN: 1354523X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1601-0825.1998.tb00291.x     Document Type: Review

References (9)

1. Agguirre-Zero O, Zero DT, Proskin HM (1993). Effect of chewing xylitol chewing gum on salivary flow rate and the acidogenic potential of a dental plaque. Caries Res 27: 55-59.
2. Arends J, Christoffersen J, Schuthof J et al (1984). Influence of xylitol on demineralization of enamel. Caries Res 18: 296-301.
3. Assev S, Rölla G (1984). Evidence for presence of a xylitol phosphotransferase system in Streptococcus mutans OMZ 176. Acta Path Microbiol Immunol Scand Sect B 92: 89-92.
4. Assev S, Rölla G (1986). Further studies on the growth inhibition of Streptococcus mutans OMZ 176 by xylitol. Acta Path Microbiol Immumol Scand Sect B 94: 97-102.
5. Kandelman D, Gagnon G (1990). A 24-month clinical study of the incidence and progression of dental caries in relation to consumption of chewing gum containing xylitol in school preventive programs. J Dent Res 69: 1771-1775.
6. Khambanonda S, Chandravejjsmarn R, Barmes DE et al (1983). Prévention de la carie dentaire en Thailande: trois produits fluorés soumis à des tests comparatifs. J Biol Buccal 11: 255-263.
7. Larmas M, Scheinin A, Gehring F et al (1975). Turku sugar studies XX. Microbiological findings and plaque index values in relation to 1-year use of xylitol chewing gum. Acta Odont Scand 33 (Suppl 70): 321-336.
8. Wåler SM, Rölla G (1983). Effect of xylitol on dental plaque in vivo during carbohydrate challenge. Scand J Dent Res 91: 256-259.
9. Wennerholm K, Arends J, Birkhed D et al (1994). Effect of xylitol and sorbitol in chewing-gums on mutans streptococci, plaque pH and mineral loss of enamel. Caries Res 28: 48-54.