Cross-talk between mesenchyme and epithelium increases H19 gene expression during scattering and morphogenesis of epithelial cells

Experimental Cell Research

Volumn 275, Issue 2, 2002, Pages 215-229

  Adriaenssens, Eric ^a,b   Lottin, Séverine ^a   Berteaux, Nathalie ^a   Hornez, Louis ^c   Fauquette, William ^a   Fafeur, Véronique ^b   Peyrat, Jean Philippe ^c   Le Bourhis, Xuefen ^a   Hondermarck, Hubert ^a   Coll, Jean ^b   Dugimont, Thierry ^a   Curgy, Jean Jacques ^a  

^a UNIV LILLE   (France)

^b INSTITUT DE BIOLOGIE DE LILLE   (France)

^c CENTRE OSCAR LAMBRET   (France)

Author keywords

Epithelium mesenchyme interactions; Extracellular matrix; H19 gene; HGF SF; Morphogenesis; Scattering

Indexed keywords

COLLAGEN GEL; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C; PLASTIC; PROTEIN ANTIBODY; SCATTER FACTOR; SOMATOMEDIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BREAST EPITHELIUM; CELL CULTURE; CELL GROWTH; CELL INVASION; CELL MIGRATION; CELL STRAIN; CELL STRAIN MCF 7; CELL STRUCTURE; CONTROLLED STUDY; CULTURE MEDIUM; EMBRYO; EPITHELIUM CELL; FIBROBLAST; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; MESENCHYME; MORPHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSACTIVATION;

MINK CELL FOCUS-FORMING VIRUS;

EID: 0036351329     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.2002.5500     Document Type: Article

References (100)

1. Epithelial morphogenesis
2. Influence of collagen gel on the orientation of epithelial cell polarity: Follicle formation from isolated thyroid cells and from pre-formed monolayers
3. Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors
4. Characterization of morphogenetic and invasive abilities of human mammary epithelial cells: Correlation with variations of urokinase-type plasminogen activator activity and type-1 plasminogen activator inhibitor level
5. Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor
6. A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor
7. Induction of epithelial branching tubulogenesis in vitro
8. Plasminogen activator inhibitor-1 is induced in migrating endothelial cells
9. A fine-structure deletion map of human chromosome 11p: Analysis of J1 series hybrids
10. Relaxation of imprinted genes in human cancer
11. An enhancer deletion affects both H19 and Igf2 expression
12. Epigenetic mechanisms underlying the imprinting of the mouse H19 gene
13. Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2
14. Enhancer competition between H19 and Igf2 does not mediate their imprinting
15. H19 is imprinted in the choroid plexus and leptomeninges of the mouse foetus
16. Establishment of functional imprinting of the H19 gene in human developing placentae
17. Allele-specific in situ hybridization (ASISH) analysis: A novel technique which resolves differential allelic usage of H19 within the same cell lineage during human placental development
18. Biallelic expression of the H19 and IGF2 genes in human testicular germ cell tumors
19. Loss of imprinting of IGF2 and not H19 in breast cancer, adjacent normal tissue and derived fibroblast cultures
20. The protein CTCF is required for the enhancer blocking activity of vertebrate insulators
21. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
22. CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus
23. Genomic imprinting. Silence across the border
24. The structure and expression of a novel gene activated in early mouse embryogenesis
25. Evidence for evolutionarily conserved secondary structure in the H19 tumor suppressor RNA
26. The 5′ part of the human H19 RNA contains cis-acting elements hampering its translatability
27. The H19 transcript is associated with polysomes and may regulate IGF2 expression in trans
28. H19 sense and antisense transgenes modify insulin-like growth factor-II mRNA levels
29. The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo
30. The human ASM (adult skeletal muscle) gene: Expression and chromosomal assignment to 11p15
31. Expression of the human foetal BAC/H19 gene in invasive cancers
32. The H19 gene is expressed within both epithelial and stromal components of human invasive adenocarcinomas
33. H19 and insulin-like growth factor-II gene expression in adrenal tumors and cultured adrenal cells
34. The product of the imprinted H19 gene is an oncofetal RNA
35. H19 expression and tumorigenicity of choriocarcinoma derived cell lines
36. Developmentally imprinted genes as markers for bladder tumor progression
37. High incidence of loss of heterozygosity and abnormal imprinting of H19 and IGF2 genes in invasive cervical carcinomas. Uncoupling of H19 and IGF2 expression and biallelic hypomethylation of H19
38. H19 overexpression in breast adenocarcinoma stromal cells is associated with tumor values and steroid receptor status but independent of p53 and Ki-67 expression
39. Frequent loss of imprinting of the H19 gene is often associated with its overexpression in human lung cancers
40. Loss of imprinting in hepatoblastoma
41. Loss of H19 imprinting in esophageal cancer
42. Biallelic expression of the H19 and IGF2 genes in hepatocellular carcinoma
43. Molecular evolutionary evidence that H19 mRNA is functional
44. Genomic imprinting and Wilms' tumor
45. Inactivation of H19, an imprinted and putative tumor repressor gene, is a preneoplastic event during Wilms' tumorigenesis
46. Epigenetic changes at the insulin-like growth factor II/H19 locus in developing kidney is an early event in Wilms tumorigenesis
47. Tumour-suppressor activity of H19 RNA
48. Chromosome 11p15.5 regional imprinting: Comparative analysis of KIP2 and H19 in human tissues and Wilms' tumors
49. The expression of the H19 gene and its function in human bladder carcinoma cell lines
50. The expression of the imprinted H19 and IGF-2 genes in human bladder carcinoma
51. Association of IGF2 and H19 imprinting with choriocarcinoma development
52. Unique expression patterns of H19 in human testicular cancers of different etiology
53. Imprinted H19 oncofetal RNA is a candidate tumour marker for hepatocellular carcinoma
54. The imprinted H19 gene is a marker of early recurrence in human bladder carcinoma
55. H19, a marker of developmental transition, is reexpressed in human atherosclerotic plaques and is regulated by the insulin family of growth factors in cultured rabbit smooth muscle cells
56. Parallel regulation of parentally imprinted H19 and insulin-like growth factor-II genes in cultured human fetal adrenal cells
57. Expression patterns of c-myb and of v-myb induced myeloid-1 (mim-1) gene during the development of the chick embryo
58. Prognostic value of the type I growth factor receptors in a large series of human primary breast cancers quantified with a real-time reverse transcription-polymerase chain reaction assay
59. Real-time reverse transcription-PCR assay for future management of ERBB2-based clinical applications
60. Kinetic PCR analysis: Real-time monitoring of DNA amplification reactions
61. The H19 TATA-less promoter is efficiently repressed by wild-type tumor suppressor gene product p53
62. The proliferative and migratory activities of breast cancer cells can be differentially regulated by heparan sulfates
63. Junctional competence in clones of mammary epithelial cells, and modulation by conditioned medium
64. Scatter factor is a fibroblast-derived modulator of epithelial cell mobility
65. Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development
66. Fibroblast-mediated acceleration of human epithelial tumor growth in vivo
67. Human skin fibroblasts induce anchorage-independent growth of HPV-16- DNA-immortalized cervical epithelial cells
68. Malignant transformation of mouse primary keratinocytes by Harvey sarcoma virus and its modulation by surrounding normal cells
69. Role of mesenchymal-epithelial interactions in normal and abnormal development of the mammary gland and prostate
70. The role of fibroblasts in tumor behavior
71. The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells
72. Hepatocyte growth factor/scatter factor induces a variety of tissue- specific morphogenic programs in epithelial cells
73. Met signaling mutants as tools for developmental studies
74. Hepatocyte growth factor and neuregulin in mammary gland cell morphogenesis
75. Hepatocyte growth factor down-regulates the alpha-fetoprotein gene expression in PLC/PRF/5 human hepatoma cells
76. Locus unlinked to alpha-fetoprotein under the control of the murine raf and Rif genes
77. The tyrosine-phosphorylated hepatocyte growth factor/ scatter factor receptor associates with phosphatidylinositol 3-kinase
78. Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells
79. Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase
80. Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility
81. Induction of epithelial tubules by growth factor HGF depends on the STAT pathway
82. Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis
83. Met receptor tyrosine kinase: Enhanced signaling through adapter proteins
84. Steroid hormones modulate H19 gene expression in both mammary gland and uterus
85. Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element
86. The activation and composition of FiRE (an FGF-inducible response element) differ in a cell type- and growth factor-specific manner
87. Role of cell shape in growth control
88. Prolonged expression of differentiated phenotype by chondrocytes cultured at low density on a composite substrate of collagen and agarose that restricts cell spreading
89. Extracellular matrix and cell shape: Potential control points for inhibition of angiogenesis
90. The riddle of morphogenesis: A question of solution chemistry or molecular cell engineering?
91. Cellular tensegrity: Defining new rules of biological design that govern the cytoskeleton
92. Switching from differentiation to growth in hepatocytes: Control by extracellular matrix
93. H19, a developmentally regulated gene, is reexpressed in rat vascular smooth muscle cells after injury
94. Isolation of differentially expressed human cDNA clones: Similarities between mouse and human embryonal carcinoma cell differentiation
95. Imprinted genes are up-regulated by growth arrest in embryonic fibroblasts
96. Expression of a single transfected cDNA converts fibroblasts to myoblasts
97. Expression of the c-Met/HGF receptor in human breast carcinoma: Correlation with tumor progression
98. Differential gene expression in tumorigenic and nontumorigenic HeLa x normal human fibroblast hybrid cells
99. Examination of the oncogenic potential of H19 gene in HeLa x normal human fibroblast hybrid cells
100. Mesenchymal-epithelial transition in the developing metanephric kidney: Gene expression study by differential display