Macrophage inducible nitric oxide synthase gene expression is blocked by a benzothiophene derivative with anti-HIV properties

Molecular Genetics and Metabolism

Volumn 75, Issue 4, 2002, Pages 360-368

  Carballo, M ^a   Conde, M ^a   Tejedo, J ^a   Gualberto, A ^c   Jimenez, J ^a   Monteseirin J ^b   Santa Maria C ^b   Bedoya, F J ^a   Hunt Iii, S W ^d   Pintado, E ^a   Baldwin Jr , A S ^d   Sobrino, F ^a,b  

^a UNIVERSITY OF SEVILLE   (Spain)

^b UNIVERSITY OF SEVILLE   (Spain)

^c ST ELIZABETH'S MEDICAL CENTER   (United States)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Benzothiophene derivative (PD144795); Immunosuppression; iNOS; Macrophage; Nitric oxide

Indexed keywords

BENZOTHIOPHENE 2 CARBOXAMIDE, 5 METHOXY 3 (1 METHYLETHOXY) 1 OXIDE; BENZOTHIOPHENE DERIVATIVE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE SYNTHASE; NITRITE; PD 144795; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; GENE EXPRESSION; GENE TRANSLOCATION; HUMAN IMMUNODEFICIENCY VIRUS; INHIBITION KINETICS; MACROPHAGE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL;

ANIMALS; ANTI-HIV AGENTS; CELL LINE; CELLS, CULTURED; GENE EXPRESSION; IMMUNOSUPPRESSIVE AGENTS; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; THIOPHENES;

BACTERIA (MICROORGANISMS);

EID: 0036351121     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1096-7192(02)00001-X     Document Type: Article

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