Antiepileptic drugs to prevent neural degeneration associated with epilepsy: Assessing the prospects for neuroprotection

Epilepsy Research

Volumn 50, Issue 1-2, 2002, Pages 125-129

  Sutula, Thomas ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Anti degenerative drugs; Antiepileptic drugs; Epilepsy; Neural degeneration; Neuroprotection

Indexed keywords

ANTICONVULSIVE AGENT;

CONFERENCE PAPER; DISEASE ASSOCIATION; EPILEPSY; EPILEPTOGENESIS; GENETIC SUSCEPTIBILITY; HUMAN; NERVE CELL DEGENERATION; NEUROPROTECTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

ANIMALS; ANTICONVULSANTS; EPILEPSY; HUMANS; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; SEIZURES; TREATMENT OUTCOME;

EID: 0036342432     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(02)00074-8     Document Type: Conference Paper

References (22)

1. Evidence suggesting secondary epileptogenic lesions after kainic acid: Pre-treatment with diazepam reduces distant but not local damage
2. Comparison of valproate and phenobarbital treatment after status epilepticus in rats
3. Entorhinal cortex of the rat: Topographic organization of the cells of origin of the perforant path projection to the dentate gyrus
4. MRI studies: Do seizures damage the brain
5. Neuroimaging methods to evaluate the etiology and consequences of epilepsy
6. Distribution of spatial and nonspatial information in dorsal hippocampus
7. Effects of chronic epilepsy on declarative memory systems
8. The neurodevelopmental impact of childhood onset temporal lobe epilepsy on brain structure and function andnthe risk of progressive cognitive effects
9. Effects of epilepsy on intellectual functions
10. Hippocampal kindling protects several structures from the neuronal damage resulting from kainic acid induced status epilepticus
11. Repeated brief seizures induce progressive hippocampal neuron loss and memory deficits
12. Systemic factors and epileptic brain damage: Prolonged seizures in paralyzed artificially ventilated baboons
13. Efficacy of current antiepileptics to prevent neurodegeneration in epilepsy models
14. Progression of neuronal damage after status epilepticus and during spontaneous seizures in a rat model of temporal lobe epilepsy
15. Do seizures damage the Brain?
16. Genetic determinants of susceptibility to excitotoxic cell death: Implications for gene targeting approaches
17. Complication associated with genetic background effects in models of experimental epilepsy
18. Is neurodegeneration responsible for memory and behavioral alterations in epilepsy?
19. Alteration of long-lasting structural and functional effects of kainic acid in the hippocampus by brief treatment with phenobarbital
20. Magnetic resonance imaging evidence of hippocampal injury after prolonged focal febrile convulsions
21. Enhanced GABAergic inihibition preserves hippocampal structure and function in a model of epilepsy