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Volumn 10, Issue 10, 2002, Pages 3257-3265
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TX-1123: An antitumor 2-hydroxyarylidene-4-cyclopentene-1,3-dione as a protein tyrosine kinase inhibitor having low mitochondrial toxicity
a
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Author keywords
[No Author keywords available]
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Indexed keywords
2 [(3,5 DI TERT BUTYL 4 HYDROXYPHENYL)METHYLENE] 4 CYCLOPENTENE 1,3 DIONE;
2 [(3,5 DI TERT BUTYL 4 METHOXYPHENYL)METHYLENE] 4 CYCLOPENTENE 1,3 DIONE;
2 [(3,5 DI TERT BUTYL 4 METHOXYPHENYL)METHYLENE]MALONITRILE;
3,5 DI TERT BUTYL 4 HYDROXYBENZYLIDENEMALONONITRILE;
ANTINEOPLASTIC AGENT;
CYCLOPENTANE DERIVATIVE;
ENZYME INHIBITOR;
PROTEIN TYROSINE KINASE INHIBITOR;
TYRPHOSTIN;
UNCLASSIFIED DRUG;
2 HYDROXYARYLIDENE 4 CYCLOPENTENE 1,3 DIONE;
2-HYDROXYARYLIDENE-4-CYCLOPENTENE-1,3-DIONE;
BENZYLIDENE DERIVATIVE;
CALMODULIN DEPENDENT PROTEIN KINASE III;
CALMODULIN-DEPENDENT PROTEIN KINASE III;
CYCLOPENTANONE;
PROTEIN KINASE (CALCIUM,CALMODULIN);
PROTEIN TYROSINE KINASE;
ANIMAL CELL;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
CONTROLLED STUDY;
CYTOTOXICITY;
DRUG DESIGN;
DRUG SYNTHESIS;
IN VITRO STUDY;
NONHUMAN;
STRUCTURE ACTIVITY RELATION;
CELL CULTURE;
CELL DIVISION;
CHEMISTRY;
DRUG ANTAGONISM;
DRUG EFFECT;
HUMAN;
LIVER CELL;
MITOCHONDRION;
SYNTHESIS;
ANTINEOPLASTIC AGENTS;
BENZYLIDENE COMPOUNDS;
CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE;
CELL DIVISION;
CYCLOPENTANES;
ENZYME INHIBITORS;
HEPATOCYTES;
HUMANS;
MITOCHONDRIA;
PROTEIN-TYROSINE KINASES;
SRC-FAMILY KINASES;
STRUCTURE-ACTIVITY RELATIONSHIP;
TUMOR CELLS, CULTURED;
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EID: 0036339596
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/S0968-0896(02)00160-8 Document Type: Article |
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Times cited : (56)
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References (40)
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